SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z0u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 GLY A 510
PHE A 476
SER A 469
GLY A 513
 None
 0.71A 1d0vA-5z0uA:
undetectable		 1d0vA-5z0uA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		6 / 12 HIS A 221
TYR A 223
GLU A 396
HIS A 471
ASP A 516
ARG A 520
 MPD  A 704 (-4.0A)
None
None
None
None
None
 0.97A 1dedA-5z0uA:
34.6		 1dedA-5z0uA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		7 / 12 HIS A 221
TYR A 223
LEU A 311
ASP A 356
HIS A 471
ASP A 516
ARG A 520
 MPD  A 704 (-4.0A)
None
None
None
None
None
None
 0.81A 1dedA-5z0uA:
34.6		 1dedA-5z0uA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		8 / 12 HIS A 221
TYR A 223
LEU A 316
ASP A 356
ALA A 357
HIS A 471
ASP A 516
ARG A 520
 MPD  A 704 (-4.0A)
None
None
None
None
None
None
None
 0.73A 1dedA-5z0uA:
34.6		 1dedA-5z0uA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		6 / 12 TYR A 223
GLU A 396
HIS A 471
ASP A 472
ASP A 516
ARG A 520
 None
 0.98A 1dedA-5z0uA:
34.6		 1dedA-5z0uA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		7 / 12 TYR A 223
LEU A 311
ASP A 356
HIS A 471
ASP A 472
ASP A 516
ARG A 520
 None
 0.97A 1dedA-5z0uA:
34.6		 1dedA-5z0uA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		8 / 12 TYR A 223
LEU A 316
ASP A 356
ALA A 357
HIS A 471
ASP A 472
ASP A 516
ARG A 520
 None
 0.72A 1dedA-5z0uA:
34.6		 1dedA-5z0uA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		9 / 12 HIS A 221
TYR A 223
ARG A 354
ASP A 356
ALA A 357
GLU A 396
HIS A 471
ASP A 472
ARG A 520
 MPD  A 704 (-4.0A)
None
None
None
None
None
None
None
None
 0.68A 1dedB-5z0uA:
42.0		 1dedB-5z0uA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		7 / 12 HIS A 221
TYR A 223
ASP A 356
GLU A 396
PHE A 417
HIS A 471
ARG A 520
 MPD  A 704 (-4.0A)
None
None
None
None
None
None
 1.33A 1dedB-5z0uA:
42.0		 1dedB-5z0uA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		9 / 12 TYR A 223
LEU A 316
ARG A 354
ASP A 356
ALA A 357
GLU A 396
HIS A 471
ASP A 472
ARG A 520
 None
 0.72A 1dedB-5z0uA:
42.0		 1dedB-5z0uA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 GLY A 510
PHE A 476
SER A 469
GLY A 513
 None
 0.69A 1jhaA-5z0uA:
undetectable		 1jhaA-5z0uA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 HIS A 267
GLY A 312
ALA A 357
GLU A 396
ASP A 472
 None
 1.02A 1kxhA-5z0uA:
21.4		 1kxhA-5z0uA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		7 / 12 TYR A 223
HIS A 267
ARG A 354
ASP A 356
GLU A 396
HIS A 471
ASP A 472
 None
 0.38A 1mxdA-5z0uA:
26.9		 1mxdA-5z0uA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 9 ALA A 357
ASN A 266
TYR A 360
PHE A 313
GLY A 312
 None
None
None
MPD  A 704 (-4.2A)
None
 1.10A 1ru9H-5z0uA:
4.5
1ru9L-5z0uA:
6.3		 1ru9H-5z0uA:
undetectable
1ru9L-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 10 ALA A 357
ASN A 266
TYR A 360
PHE A 313
GLY A 312
 None
None
None
MPD  A 704 (-4.2A)
None
 1.12A 1ruaH-5z0uA:
4.4
1ruaL-5z0uA:
6.3		 1ruaH-5z0uA:
undetectable
1ruaL-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_SAMB293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 TYR A 297
ALA A 340
ASN A 335
SER A 338
TYR A 321
 None
 1.47A 1xvaB-5z0uA:
1.0		 1xvaB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 TYR A 488
TYR A 631
TRP A 485
HIS A 614
 None
 1.11A 2ha2A-5z0uA:
undetectable		 2ha2A-5z0uA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 TYR A 488
TYR A 631
TRP A 485
HIS A 614
 None
 1.16A 2ha2B-5z0uA:
undetectable		 2ha2B-5z0uA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 6 LEU A 344
PHE A 380
ILE A 393
ALA A 391
 None
 0.91A 2j5mA-5z0uA:
undetectable		 2j5mA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 141
SER A 522
SER A 171
ASP A 151
 None
None
None
CA  A 702 (-3.2A)
 0.99A 2obvA-5z0uA:
undetectable		 2obvA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 HIS A 630
SER A 425
PHE A 476
ASP A 483
 None
 1.13A 2obvA-5z0uA:
undetectable		 2obvA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 141
SER A 522
SER A 171
ASP A 151
 None
None
None
CA  A 702 (-3.2A)
 0.94A 2p02A-5z0uA:
undetectable		 2p02A-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 HIS A 630
SER A 425
PHE A 476
ASP A 483
 None
 1.19A 2p02A-5z0uA:
undetectable		 2p02A-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 10 ASP A 446
ILE A 492
THR A 561
ILE A 544
GLY A 571
 None
 1.28A 2v0mA-5z0uA:
undetectable		 2v0mA-5z0uA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XUD_A_DMEA1544_1
(ACETYLCHOLINESTERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 6 TYR A 488
TYR A 631
TRP A 485
HIS A 614
 None
 1.19A 2xudA-5z0uA:
undetectable		 2xudA-5z0uA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		6 / 12 ARG A 354
ASP A 356
ALA A 357
GLU A 396
HIS A 471
ASP A 472
 None
 0.67A 3aicA-5z0uA:
6.2		 3aicA-5z0uA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		6 / 12 ARG A 354
ASP A 356
ALA A 357
GLU A 396
HIS A 471
ASP A 472
 None
 0.69A 3aicB-5z0uA:
2.3		 3aicB-5z0uA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		7 / 12 ARG A 354
ASP A 356
ALA A 357
GLU A 396
HIS A 471
ASP A 472
TYR A 223
 None
 0.68A 3aicC-5z0uA:
6.4		 3aicC-5z0uA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		6 / 12 ARG A 354
ASP A 356
ALA A 357
GLU A 396
HIS A 471
ASP A 472
 None
 0.74A 3aicD-5z0uA:
6.5		 3aicD-5z0uA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		6 / 12 ARG A 354
ASP A 356
ALA A 357
GLU A 396
HIS A 471
ASP A 472
 None
 0.73A 3aicE-5z0uA:
7.4		 3aicE-5z0uA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		6 / 12 ARG A 354
ASP A 356
ALA A 357
GLU A 396
HIS A 471
ASP A 472
 None
 0.70A 3aicF-5z0uA:
7.4		 3aicF-5z0uA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		6 / 12 ARG A 354
ASP A 356
ALA A 357
GLU A 396
HIS A 471
ASP A 472
 None
 0.66A 3aicG-5z0uA:
6.4		 3aicG-5z0uA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		6 / 12 LEU A 311
ARG A 354
ASP A 356
GLU A 396
HIS A 471
ASP A 472
 None
 1.01A 3aicG-5z0uA:
6.4		 3aicG-5z0uA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		6 / 12 ARG A 354
ASP A 356
ALA A 357
GLU A 396
HIS A 471
ASP A 472
 None
 0.75A 3aicH-5z0uA:
6.3		 3aicH-5z0uA:
6.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 HIS A 630
GLY A 629
ASN A 584
TRP A 427
 None
 1.04A 3ccfA-5z0uA:
undetectable		 3ccfA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 THR A  33
ILE A 120
TYR A  90
GLN A  16
THR A 458
 None
 1.42A 3elzC-5z0uA:
2.6		 3elzC-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 LEU A 583
THR A 496
ASP A 609
LEU A 537
LEU A 541
 None
 1.06A 3g1uC-5z0uA:
undetectable		 3g1uC-5z0uA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 LEU A 583
THR A 496
ASP A 609
LEU A 537
LEU A 541
 None
 0.99A 3glqA-5z0uA:
undetectable		 3glqA-5z0uA:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 LEU A 583
THR A 496
ASP A 609
LEU A 537
LEU A 541
 None
 0.99A 3n58A-5z0uA:
undetectable		 3n58A-5z0uA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 LEU A 583
THR A 496
ASP A 609
LEU A 537
LEU A 541
 None
 1.02A 3n58D-5z0uA:
undetectable		 3n58D-5z0uA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		3 / 3 LYS A 385
ARG A 381
ASP A 128
 None
 1.13A 3o7wA-5z0uA:
undetectable		 3o7wA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 TYR A 228
TYR A 321
LEU A 355
TRP A 377
 None
 0.87A 3uzzB-5z0uA:
10.0		 3uzzB-5z0uA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		3 / 3 TYR A 505
ARG A 142
SER A 522
 None
 1.06A 4dr2I-5z0uA:
undetectable
4dr2J-5z0uA:
undetectable		 4dr2I-5z0uA:
22.02
4dr2J-5z0uA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 11 TYR A 488
TYR A 631
TRP A 485
HIS A 614
GLY A 613
 None
 1.11A 4ey7A-5z0uA:
undetectable		 4ey7A-5z0uA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 11 TYR A 488
TYR A 631
TRP A 485
HIS A 614
GLY A 613
 None
 1.13A 4ey7B-5z0uA:
undetectable		 4ey7B-5z0uA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 7 ILE A 473
ARG A 479
ARG A 475
MET A 135
 None
 1.28A 4f4dA-5z0uA:
undetectable		 4f4dA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ILE A 473
ARG A 479
ARG A 475
MET A 135
 None
 1.34A 4f4dB-5z0uA:
undetectable		 4f4dB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 10 PHE A 235
ALA A 191
LEU A 190
GLY A 236
MET A 465
 None
 1.42A 4fe1A-5z0uA:
undetectable
4fe1J-5z0uA:
undetectable		 4fe1A-5z0uA:
8.25
4fe1J-5z0uA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 7 ASP A 356
ASP A 516
ASP A 472
GLU A 396
 None
 1.17A 4feuB-5z0uA:
3.0		 4feuB-5z0uA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 7 ASP A 356
ASP A 516
ASP A 472
GLU A 396
 None
 1.19A 4fevD-5z0uA:
3.4		 4fevD-5z0uA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 7 ASP A 356
ASP A 516
ASP A 472
GLU A 396
 None
 1.20A 4fevF-5z0uA:
3.2		 4fevF-5z0uA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 356
ASP A 516
ASP A 472
GLU A 396
 None
 1.18A 4fewD-5z0uA:
undetectable		 4fewD-5z0uA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 356
ASP A 516
ASP A 472
GLU A 396
 None
 1.19A 4fewF-5z0uA:
3.6		 4fewF-5z0uA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 6 ARG A 475
GLY A 510
GLN A 494
MET A 495
 None
 0.99A 4g0vB-5z0uA:
undetectable		 4g0vB-5z0uA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		3 / 3 GLU A 426
ASP A 432
ASP A 418
 None
 0.68A 4gc9A-5z0uA:
undetectable		 4gc9A-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 7 ASP A 356
ASP A 516
ASP A 472
GLU A 396
 None
 1.18A 4gkhG-5z0uA:
2.4		 4gkhG-5z0uA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 356
ASP A 516
ASP A 472
GLU A 396
 None
 1.18A 4gkiA-5z0uA:
2.0		 4gkiA-5z0uA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 356
ASP A 516
ASP A 472
GLU A 396
 None
 1.19A 4gkiC-5z0uA:
3.3		 4gkiC-5z0uA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 11 GLU A  25
SER A 463
LEU A 130
ILE A 394
LEU A 355
 None
 1.47A 4k37A-5z0uA:
3.3		 4k37A-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME
KP18CYS PEPTIDE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 GLU A  25
SER A 463
LEU A 130
ILE A 394
LEU A 355
 None
 1.49A 4k38A-5z0uA:
3.6
4k38D-5z0uA:
undetectable		 4k38A-5z0uA:
undetectable
4k38D-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 GLU A  25
SER A 463
LEU A 130
ILE A 394
LEU A 355
 None
 1.44A 4k39A-5z0uA:
3.5		 4k39A-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 141
SER A 522
SER A 171
ASP A 151
 None
None
None
CA  A 702 (-3.2A)
 1.03A 4kttA-5z0uA:
undetectable		 4kttA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 HIS A 630
SER A 425
PHE A 476
ASP A 483
 None
 1.16A 4kttA-5z0uA:
undetectable		 4kttA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 141
SER A 522
SER A 171
ASP A 151
 None
None
None
CA  A 702 (-3.2A)
 0.96A 4kttC-5z0uA:
undetectable		 4kttC-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 HIS A 630
SER A 425
PHE A 476
ASP A 483
 None
 1.15A 4kttC-5z0uA:
undetectable		 4kttC-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 507
SER A 469
ALA A 477
SER A 480
 None
 1.04A 4lv9A-5z0uA:
4.5
4lv9B-5z0uA:
4.5		 4lv9A-5z0uA:
11.18
4lv9B-5z0uA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 7 ASP A 507
SER A 469
ALA A 477
SER A 480
 None
 1.02A 4lv9A-5z0uA:
4.1
4lv9B-5z0uA:
4.7		 4lv9A-5z0uA:
11.18
4lv9B-5z0uA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 141
SER A 522
SER A 171
ASP A 151
 None
None
None
CA  A 702 (-3.2A)
 0.95A 4ndnA-5z0uA:
undetectable		 4ndnA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 VAL A 361
GLY A 395
TYR A 397
ILE A 394
GLN A 137
 None
 1.38A 4xucA-5z0uA:
undetectable		 4xucA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 141
SER A 522
SER A 171
ASP A 151
 None
None
None
CA  A 702 (-3.2A)
 0.94A 5a1iA-5z0uA:
undetectable		 5a1iA-5z0uA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 HIS A 630
SER A 425
PHE A 476
ASP A 483
 None
 1.16A 5a1iA-5z0uA:
undetectable		 5a1iA-5z0uA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 TYR A 570
ASP A 609
ILE A 492
LEU A 541
THR A 496
 None
 1.27A 5b8hA-5z0uA:
undetectable
5b8hB-5z0uA:
undetectable		 5b8hA-5z0uA:
undetectable
5b8hB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 LEU A 541
THR A 496
TYR A 570
ASP A 609
ILE A 492
 None
 1.28A 5b8hA-5z0uA:
undetectable
5b8hB-5z0uA:
undetectable		 5b8hA-5z0uA:
undetectable
5b8hB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 ARG A 354
ASP A 356
GLU A 396
HIS A 471
ASP A 472
 None
 0.45A 5csyB-5z0uA:
19.8		 5csyB-5z0uA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 11 VAL A 594
VAL A 625
VAL A 592
ILE A 492
LEU A 635
 None
 1.12A 5e4dB-5z0uA:
undetectable		 5e4dB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 6 LEU A 449
THR A 421
TRP A 398
GLN A 434
 None
 1.40A 5h8tA-5z0uA:
undetectable		 5h8tA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I71_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 TYR A 570
GLY A 419
PHE A 420
GLY A 499
VAL A 424
 None
 1.22A 5i71A-5z0uA:
undetectable		 5i71A-5z0uA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 GLY A 613
VAL A 625
THR A 624
ALA A 636
LEU A 635
 None
 0.83A 5kocA-5z0uA:
undetectable		 5kocA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 10 GLY A 510
ILE A 428
LEU A 489
LEU A 491
ALA A 490
 None
 1.02A 5l0zB-5z0uA:
3.3		 5l0zB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 SER A 600
ASP A  69
PRO A  70
SER A  67
 None
 1.12A 5l1fA-5z0uA:
undetectable
5l1fB-5z0uA:
undetectable		 5l1fA-5z0uA:
9.14
5l1fB-5z0uA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 5 VAL A 231
ASN A 150
ASP A 189
LEU A 190
 None
CA  A 702 (-3.1A)
CA  A 702 (-3.3A)
None
 1.35A 5m0iB-5z0uA:
undetectable		 5m0iB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 HIS A 630
SER A 425
PHE A 476
ASP A 483
 None
 1.12A 5t8sB-5z0uA:
undetectable		 5t8sB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 TYR A 223
HIS A 267
ASP A 356
HIS A 471
ASP A 472
 None
 0.64A 6ag0A-5z0uA:
25.1		 6ag0A-5z0uA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 9 VAL A 623
GLY A 571
LEU A 599
GLN A 598
VAL A 582
 None
 1.33A 6czmA-5z0uA:
undetectable
6czmB-5z0uA:
undetectable		 6czmA-5z0uA:
undetectable
6czmB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 141
SER A 522
SER A 171
ASP A 151
 None
None
None
CA  A 702 (-3.2A)
 0.97A 6fbnB-5z0uA:
undetectable		 6fbnB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 HIS A 630
SER A 425
PHE A 476
ASP A 483
 None
 1.12A 6fbnB-5z0uA:
undetectable		 6fbnB-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 141
SER A 522
SER A 171
ASP A 151
 None
None
None
CA  A 702 (-3.2A)
 0.96A 6fboA-5z0uA:
undetectable		 6fboA-5z0uA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 HIS A 630
SER A 425
PHE A 476
ASP A 483
 None
 1.16A 6fboA-5z0uA:
undetectable		 6fboA-5z0uA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 141
SER A 522
SER A 171
ASP A 151
 None
None
None
CA  A 702 (-3.2A)
 1.04A 6fcbA-5z0uA:
undetectable		 6fcbA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 HIS A 630
SER A 425
PHE A 476
ASP A 483
 None
 1.10A 6fcbA-5z0uA:
undetectable		 6fcbA-5z0uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 ASP A 141
SER A 522
SER A 171
ASP A 151
 None
None
None
CA  A 702 (-3.2A)
 0.96A 6fcdA-5z0uA:
undetectable		 6fcdA-5z0uA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		4 / 8 HIS A 630
SER A 425
PHE A 476
ASP A 483
 None
 1.14A 6fcdA-5z0uA:
undetectable		 6fcdA-5z0uA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_1
(-)		 5z0u NEOPULLULANASE 1
(Thermoactinomyce
s
vulgaris) 		5 / 12 LEU A 583
THR A 496
ASP A 609
LEU A 537
LEU A 541
 None
 1.06A 6gbnC-5z0uA:
undetectable		 6gbnC-5z0uA:
13.85