SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z1g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 5z1g RRNA-PROCESSING
PROTEIN EBP2
(Saccharomyces
cerevisiae) 		4 / 6 ALA A 245
LYS A 248
ASP A 252
ALA A 253
 None
 0.38A 1iwhA-5z1gA:
undetectable		 1iwhA-5z1gA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 5z1g RIBOSOME BIOGENESIS
PROTEIN BRX1
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 156
LEU B 101
ILE B 226
TYR B 237
PHE B 112
 None
 1.23A 2weyA-5z1gB:
undetectable		 2weyA-5z1gB:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 5z1g RIBOSOME BIOGENESIS
PROTEIN BRX1
(Saccharomyces
cerevisiae) 		3 / 3 GLU B 214
GLY B 127
THR B 126
 None
 0.53A 3iazA-5z1gB:
undetectable		 3iazA-5z1gB:
12.92