SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 12 LEU A 249
TYR A 321
GLY A 353
PRO A 354
MET A 329
 None
 1.28A 1fdsA-5z24A:
undetectable		 1fdsA-5z24A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 12 LEU A 443
PHE A 363
LEU A 421
PRO A 406
VAL A 397
 None
 1.23A 1hrkA-5z24A:
undetectable		 1hrkA-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 12 LEU A 443
PHE A 363
LEU A 421
PRO A 406
VAL A 397
 None
 1.29A 1hrkB-5z24A:
undetectable		 1hrkB-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		4 / 4 ALA A 126
VAL A 117
ALA A 125
HIS A  44
 None
 1.23A 1q23F-5z24A:
undetectable		 1q23F-5z24A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 12 LEU A 443
PHE A 363
LEU A 421
PRO A 406
VAL A 397
 None
 1.32A 2pnjB-5z24A:
undetectable		 2pnjB-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 11 LEU A 443
PHE A 363
LEU A 421
PRO A 406
VAL A 397
 None
 1.32A 2po5B-5z24A:
undetectable		 2po5B-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 12 LEU A 443
PHE A 363
LEU A 421
PRO A 406
VAL A 397
 None
 1.21A 2po7B-5z24A:
undetectable		 2po7B-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 11 LEU A 436
LEU A 431
ILE A 409
THR A 378
VAL A 397
 None
 1.23A 2qd3A-5z24A:
undetectable		 2qd3A-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 12 LEU A 443
PHE A 363
LEU A 421
PRO A 406
VAL A 397
 None
 1.25A 2qd4B-5z24A:
undetectable		 2qd4B-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 PRO A 449
PHE A 379
ALA A 365
 None
 0.73A 3itaD-5z24A:
undetectable		 3itaD-5z24A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 10 TYR A 441
VAL A 463
GLY A 439
GLN A 405
GLY A 359
 None
 1.27A 3km6A-5z24A:
undetectable		 3km6A-5z24A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		4 / 6 PHE A 143
TYR A 141
VAL A 164
PHE A  41
 None
 1.19A 3ltwA-5z24A:
undetectable		 3ltwA-5z24A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		4 / 7 PHE A 274
ALA A 253
THR A 322
LEU A 265
 None
 0.81A 4ejgA-5z24A:
undetectable		 4ejgA-5z24A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		4 / 8 PHE A 274
ALA A 253
THR A 322
LEU A 265
 None
 0.92A 4ejgB-5z24A:
undetectable		 4ejgB-5z24A:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 12 LEU A 436
LEU A 431
ILE A 409
THR A 378
VAL A 397
 None
 1.25A 4f4dA-5z24A:
undetectable		 4f4dA-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 12 LEU A 436
LEU A 431
ILE A 409
THR A 378
VAL A 397
 None
 1.18A 4f4dB-5z24A:
undetectable		 4f4dB-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 10 LEU A 436
LEU A 431
ILE A 409
THR A 378
VAL A 397
 None
 1.35A 4mk4A-5z24A:
undetectable		 4mk4A-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 PHE A 461
THR A 419
LEU A 436
 None
 0.76A 4qztA-5z24A:
undetectable		 4qztA-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		4 / 8 ILE A 433
ARG A 474
LEU A 381
PHE A 461
 None
 0.88A 4v04A-5z24A:
undetectable		 4v04A-5z24A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.66A 5qgjA-5z24A:
undetectable		 5qgjA-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.64A 5qgnA-5z24A:
undetectable		 5qgnA-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.62A 5qgyA-5z24A:
undetectable		 5qgyA-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.61A 5qgzA-5z24A:
undetectable		 5qgzA-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.63A 5qh0A-5z24A:
undetectable		 5qh0A-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.62A 5qh2A-5z24A:
undetectable		 5qh2A-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.62A 5qh3A-5z24A:
undetectable		 5qh3A-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.62A 5qh5A-5z24A:
undetectable		 5qh5A-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.62A 5qh6A-5z24A:
undetectable		 5qh6A-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.62A 5qh7A-5z24A:
undetectable		 5qh7A-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.64A 5qhaA-5z24A:
undetectable		 5qhaA-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		3 / 3 VAL A 259
VAL A 317
GLN A 217
 None
 0.61A 5qhhA-5z24A:
undetectable		 5qhhA-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 12 PHE A 238
ILE A 264
VAL A 259
PHE A 216
VAL A 305
 None
 1.35A 6ap6A-5z24A:
undetectable		 6ap6A-5z24A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 5z24 PILUS ASSEMBLY
PROTEIN
(Lactobacillus
rhamnosus) 		5 / 12 PHE A 238
ILE A 264
VAL A 259
PHE A 216
VAL A 305
 None
 1.35A 6ap6B-5z24A:
undetectable		 6ap6B-5z24A:
undetectable