SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z2m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 5z2m -
(-) 		3 / 3 PHE A  33
LEU A  24
SER A 155
 GTP  A 202 (-4.2A)
None
GTP  A 202 (-3.4A)
 0.74A 1e7aA-5z2mA:
undetectable		 1e7aA-5z2mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5z2m -
(-) 		5 / 12 THR A  40
GLY A  20
GLY A  18
GLY A  66
ASP A 128
 MG  A 201 ( 3.0A)
GTP  A 202 (-3.3A)
GTP  A 202 (-3.4A)
GTP  A 202 (-3.2A)
GTP  A 202 (-2.7A)
 0.98A 2b25A-5z2mA:
2.4		 2b25A-5z2mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 5z2m -
(-) 		4 / 5 VAL A  52
LEU A 174
LEU A  56
ARG A  55
 None
 0.88A 4mghA-5z2mA:
3.3		 4mghA-5z2mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5z2m -
(-) 		5 / 12 ALA A 110
CYH A  83
GLY A  80
ILE A 169
THR A 168
 None
 0.91A 4n49A-5z2mA:
undetectable		 4n49A-5z2mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 5z2m -
(-) 		4 / 5 TYR A  78
GLU A 105
LEU A  14
GLN A  71
 None
 1.25A 4qztB-5z2mA:
undetectable		 4qztB-5z2mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 5z2m -
(-) 		5 / 9 LEU A 123
VAL A  87
VAL A  85
ILE A  61
ASP A  63
 None
None
None
None
MG  A 201 ( 3.9A)
 1.24A 5yf9X-5z2mA:
undetectable		 5yf9X-5z2mA:
undetectable