SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z2n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)
5z2n -
(-)
5 / 12 ALA B  55
ASP B  38
GLY B  48
LEU B  47
LEU B  52
None
1.35A 2nv4B-5z2nB:
undetectable
2nv4B-5z2nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X08_A_ASCA1253_0
(CYTOCHROME C
PEROXIDASE,
MITOCHONDRIAL)
5z2n -
(-)
5 / 9 ALA B  35
ASP B  36
ILE B  37
PRO B  51
ASN B   2
None
1.49A 2x08A-5z2nB:
undetectable
2x08A-5z2nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)
5z2n -
(-)
5 / 9 ASN B 111
GLY B 112
GLY B 114
GLY B  81
ASP B  82
None
1.36A 4h2fA-5z2nB:
undetectable
4h2fA-5z2nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)
5z2n -
(-)
5 / 12 LYS B  23
LEU B  25
MET B  28
ALA B  13
ILE B  37
None
1.13A 4x1iD-5z2nB:
undetectable
4x1iD-5z2nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)
5z2n -
(-)
4 / 6 LEU B 100
ALA B 105
THR B  50
ASN B  78
None
0.95A 6f88A-5z2nB:
undetectable
6f88A-5z2nB:
undetectable