SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z38'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli) 		4 / 5 THR E  19
THR E  11
GLU F  46
HIS F  43
 None
 1.42A 1d4fB-5z38E:
undetectable		 1d4fB-5z38E:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli;
Escherichia
coli) 		5 / 12 LEU E  12
VAL E  30
ILE F  14
VAL F  20
LEU F  12
 None
 1.04A 3w68C-5z38E:
undetectable		 3w68C-5z38E:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli;
Escherichia
coli) 		5 / 12 LEU F  12
VAL F  30
ILE E  14
VAL E  20
LEU E  12
 None
 0.95A 3w68C-5z38F:
undetectable		 3w68C-5z38F:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli;
Escherichia
coli) 		3 / 3 VAL F  22
VAL F   8
GLN E  29
 None
 0.66A 5qgyA-5z38F:
undetectable		 5qgyA-5z38F:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli;
Escherichia
coli) 		3 / 3 VAL F  22
VAL F   8
GLN E  29
 None
 0.64A 5qgzA-5z38F:
undetectable		 5qgzA-5z38F:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli;
Escherichia
coli) 		3 / 3 VAL F  22
VAL F   8
GLN E  29
 None
 0.66A 5qh0A-5z38F:
undetectable		 5qh0A-5z38F:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli;
Escherichia
coli) 		3 / 3 VAL F  22
VAL F   8
GLN E  29
 None
 0.65A 5qh2A-5z38F:
undetectable		 5qh2A-5z38F:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli;
Escherichia
coli) 		3 / 3 VAL F  22
VAL F   8
GLN E  29
 None
 0.64A 5qh3A-5z38F:
undetectable		 5qh3A-5z38F:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli;
Escherichia
coli) 		3 / 3 VAL F  22
VAL F   8
GLN E  29
 None
 0.65A 5qh6A-5z38F:
undetectable		 5qh6A-5z38F:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli;
Escherichia
coli) 		3 / 3 VAL F  22
VAL F   8
GLN E  29
 None
 0.66A 5qh7A-5z38F:
undetectable		 5qh7A-5z38F:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli;
Escherichia
coli) 		3 / 3 VAL F  22
VAL F   8
GLN E  29
 None
 0.64A 5qhaA-5z38F:
undetectable		 5qhaA-5z38F:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5z38 TRUNCATED-CSRA
WILD TYPE CSRA
(Escherichia
coli;
Escherichia
coli) 		3 / 3 VAL F  22
VAL F   8
GLN E  29
 None
 0.65A 5qhhA-5z38F:
undetectable		 5qhhA-5z38F:
undetectable