SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5z6v ABC-TYPE
UNCHARACTERIZED
TRANSPORT SYSTEM
PERIPLASMIC
COMPONENT-LIKE
PROTEIN
(Rhodothermus
marinus) 		3 / 3 ALA A 144
VAL A 146
TRP A 148
 None
 0.88A 1kqeA-5z6vA:
undetectable
1kqeE-5z6vA:
undetectable		 1kqeA-5z6vA:
undetectable
1kqeE-5z6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 5z6v ABC-TYPE
UNCHARACTERIZED
TRANSPORT SYSTEM
PERIPLASMIC
COMPONENT-LIKE
PROTEIN
(Rhodothermus
marinus) 		3 / 3 ALA A 144
VAL A 146
TRP A 148
 None
 0.87A 1kqeB-5z6vA:
undetectable
1kqeD-5z6vA:
undetectable		 1kqeB-5z6vA:
undetectable
1kqeD-5z6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 5z6v ABC-TYPE
UNCHARACTERIZED
TRANSPORT SYSTEM
PERIPLASMIC
COMPONENT-LIKE
PROTEIN
(Rhodothermus
marinus) 		3 / 3 TRP A 148
ALA A 144
VAL A 146
 None
 0.88A 1kqeB-5z6vA:
undetectable
1kqeD-5z6vA:
undetectable		 1kqeB-5z6vA:
undetectable
1kqeD-5z6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 5z6v ABC-TYPE
UNCHARACTERIZED
TRANSPORT SYSTEM
PERIPLASMIC
COMPONENT-LIKE
PROTEIN
(Rhodothermus
marinus) 		3 / 3 TRP A 148
ALA A 144
VAL A 146
 None
 0.87A 1kqeA-5z6vA:
undetectable
1kqeE-5z6vA:
undetectable		 1kqeA-5z6vA:
undetectable
1kqeE-5z6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 5z6v ABC-TYPE
UNCHARACTERIZED
TRANSPORT SYSTEM
PERIPLASMIC
COMPONENT-LIKE
PROTEIN
(Rhodothermus
marinus) 		5 / 11 VAL A 159
LEU A 157
ILE A  37
LYS A  38
THR A 170
 None
 1.34A 3bjwE-5z6vA:
undetectable		 3bjwE-5z6vA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 5z6v ABC-TYPE
UNCHARACTERIZED
TRANSPORT SYSTEM
PERIPLASMIC
COMPONENT-LIKE
PROTEIN
(Rhodothermus
marinus) 		5 / 12 LEU A 106
GLU A  60
VAL A  61
PRO A  30
THR A  29
 None
 1.48A 5xipD-5z6vA:
2.9		 5xipD-5z6vA:
undetectable