SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z73'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  37
ARG A  54
ASP A  55
TYR A 371
GLU A 415
 GOL  A 501 ( 3.8A)
GOL  A 501 (-4.1A)
GOL  A 501 (-2.7A)
None
None
 1.33A 1agmA-5z73A:
21.1		 1agmA-5z73A:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  37
ARG A  54
ASP A  55
TYR A 371
GLU A 415
 GOL  A 501 ( 3.8A)
GOL  A 501 (-4.1A)
GOL  A 501 (-2.7A)
None
None
 1.33A 1agmA-5z73A:
21.1		 1agmA-5z73A:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		3 / 3 ALA A 438
VAL A 379
TRP A 382
 None
 0.86A 1bdwA-5z73A:
undetectable
1bdwB-5z73A:
undetectable		 1bdwA-5z73A:
undetectable
1bdwB-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.27A 1c9sA-5z73A:
undetectable
1c9sK-5z73A:
undetectable		 1c9sA-5z73A:
undetectable
1c9sK-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.26A 1c9sC-5z73A:
undetectable
1c9sD-5z73A:
undetectable		 1c9sC-5z73A:
undetectable
1c9sD-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.26A 1c9sD-5z73A:
undetectable
1c9sE-5z73A:
undetectable		 1c9sD-5z73A:
undetectable
1c9sE-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.26A 1c9sE-5z73A:
undetectable
1c9sF-5z73A:
undetectable		 1c9sE-5z73A:
undetectable
1c9sF-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.25A 1c9sF-5z73A:
undetectable
1c9sG-5z73A:
undetectable		 1c9sF-5z73A:
undetectable
1c9sG-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.25A 1c9sG-5z73A:
undetectable
1c9sH-5z73A:
undetectable		 1c9sG-5z73A:
undetectable
1c9sH-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.25A 1c9sH-5z73A:
undetectable
1c9sI-5z73A:
undetectable		 1c9sH-5z73A:
undetectable
1c9sI-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.25A 1c9sJ-5z73A:
undetectable
1c9sK-5z73A:
undetectable		 1c9sJ-5z73A:
undetectable
1c9sK-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.26A 1c9sL-5z73A:
undetectable
1c9sM-5z73A:
undetectable		 1c9sL-5z73A:
undetectable
1c9sM-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.25A 1c9sM-5z73A:
undetectable
1c9sN-5z73A:
undetectable		 1c9sM-5z73A:
undetectable
1c9sN-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.24A 1c9sO-5z73A:
undetectable
1c9sP-5z73A:
undetectable		 1c9sO-5z73A:
undetectable
1c9sP-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.25A 1c9sS-5z73A:
undetectable
1c9sT-5z73A:
undetectable		 1c9sS-5z73A:
undetectable
1c9sT-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 235
HIS A 238
ASP A 174
LEU A 268
HIS A 197
 None
 1.47A 1d4fC-5z73A:
undetectable		 1d4fC-5z73A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 11 LEU A 137
ALA A 141
LEU A 455
MET A 312
ILE A 315
 None
 1.22A 1g50A-5z73A:
undetectable		 1g50A-5z73A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.27A 1gtfA-5z73A:
undetectable
1gtfK-5z73A:
undetectable		 1gtfA-5z73A:
undetectable
1gtfK-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 1gtfE-5z73A:
undetectable
1gtfF-5z73A:
undetectable		 1gtfE-5z73A:
undetectable
1gtfF-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.25A 1gtfF-5z73A:
undetectable
1gtfG-5z73A:
undetectable		 1gtfF-5z73A:
undetectable
1gtfG-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 1gtfO-5z73A:
undetectable
1gtfP-5z73A:
undetectable		 1gtfO-5z73A:
undetectable
1gtfP-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 1gtfP-5z73A:
undetectable
1gtfQ-5z73A:
undetectable		 1gtfP-5z73A:
undetectable
1gtfQ-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 1gtfR-5z73A:
undetectable
1gtfS-5z73A:
undetectable		 1gtfR-5z73A:
undetectable
1gtfS-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 1gtfT-5z73A:
undetectable
1gtfU-5z73A:
undetectable		 1gtfT-5z73A:
undetectable
1gtfU-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 11 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 1gtfU-5z73A:
undetectable
1gtfV-5z73A:
undetectable		 1gtfU-5z73A:
undetectable
1gtfV-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 1gtfL-5z73A:
undetectable
1gtfV-5z73A:
undetectable		 1gtfL-5z73A:
undetectable
1gtfV-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.26A 1gtnG-5z73A:
undetectable
1gtnH-5z73A:
undetectable		 1gtnG-5z73A:
undetectable
1gtnH-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 1gtnL-5z73A:
undetectable
1gtnM-5z73A:
undetectable		 1gtnL-5z73A:
undetectable
1gtnM-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.24A 1gtnN-5z73A:
undetectable
1gtnO-5z73A:
undetectable		 1gtnN-5z73A:
undetectable
1gtnO-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.29A 1gtnR-5z73A:
undetectable
1gtnS-5z73A:
undetectable		 1gtnR-5z73A:
undetectable
1gtnS-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.26A 1gtnS-5z73A:
undetectable
1gtnT-5z73A:
undetectable		 1gtnS-5z73A:
undetectable
1gtnT-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 6 TYR A 153
VAL A 225
ILE A 228
LEU A 139
 None
 1.02A 1j96A-5z73A:
undetectable		 1j96A-5z73A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  37
ARG A  54
ASP A  55
ASN A 366
TYR A 371
 GOL  A 501 ( 3.8A)
GOL  A 501 (-4.1A)
GOL  A 501 (-2.7A)
None
None
 1.12A 1lf9A-5z73A:
24.7		 1lf9A-5z73A:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		6 / 12 ALA A  37
ARG A  54
ASP A  55
ASN A 366
TYR A 371
TRP A 377
 GOL  A 501 ( 3.8A)
GOL  A 501 (-4.1A)
GOL  A 501 (-2.7A)
None
None
None
 1.22A 1lf9B-5z73A:
3.8		 1lf9B-5z73A:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 4 VAL A  57
ALA A  60
LEU A  76
PHE A  75
 None
 1.00A 1q97B-5z73A:
undetectable		 1q97B-5z73A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_1
(GLUCODEXTRANASE)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		6 / 12 ALA A  37
ARG A  54
ASP A  55
ASN A 366
TYR A 371
TRP A 377
 GOL  A 501 ( 3.8A)
GOL  A 501 (-4.1A)
GOL  A 501 (-2.7A)
None
None
None
 1.05A 1ulvA-5z73A:
11.2		 1ulvA-5z73A:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.25A 1utdC-5z73A:
undetectable
1utdD-5z73A:
undetectable		 1utdC-5z73A:
undetectable
1utdD-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.25A 1utdD-5z73A:
undetectable
1utdE-5z73A:
undetectable		 1utdD-5z73A:
undetectable
1utdE-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 11 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.24A 1utdM-5z73A:
undetectable
1utdN-5z73A:
undetectable		 1utdM-5z73A:
undetectable
1utdN-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 1utdQ-5z73A:
undetectable
1utdR-5z73A:
undetectable		 1utdQ-5z73A:
undetectable
1utdR-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 1utdR-5z73A:
undetectable
1utdS-5z73A:
undetectable		 1utdR-5z73A:
undetectable
1utdS-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A 309
ALA A 307
LEU A 311
PHE A 305
LEU A 384
 None
 1.26A 1y7iA-5z73A:
undetectable		 1y7iA-5z73A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  37
ARG A  54
ASP A  55
TYR A 371
GLU A 415
 GOL  A 501 ( 3.8A)
GOL  A 501 (-4.1A)
GOL  A 501 (-2.7A)
None
None
 1.30A 2f6dA-5z73A:
20.4		 2f6dA-5z73A:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A  37
ARG A  54
ASP A  55
TYR A 371
TRP A 377
 GOL  A 501 ( 3.8A)
GOL  A 501 (-4.1A)
GOL  A 501 (-2.7A)
None
None
 1.03A 2f6dA-5z73A:
20.4		 2f6dA-5z73A:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 ASP A 183
GLY A 193
VAL A 181
PRO A 128
VAL A 126
 None
 1.05A 2z54A-5z73A:
undetectable		 2z54A-5z73A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 ASP A 183
GLY A 193
VAL A 181
PRO A 128
VAL A 126
 None
 0.98A 3d1zA-5z73A:
undetectable		 3d1zA-5z73A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 311
ALA A 313
ILE A 314
SER A 316
ARG A 140
 None
 1.29A 3gyqA-5z73A:
undetectable
3gyqB-5z73A:
undetectable		 3gyqA-5z73A:
undetectable
3gyqB-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUM_A_CCSA375_0
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 4 GLN A 325
SER A 324
GLY A 392
LYS A 390
 None
 1.28A 3rumA-5z73A:
0.0		 3rumA-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 7 ASP A 302
TYR A 195
PRO A 198
GLN A 202
 None
 1.13A 3s3oA-5z73A:
undetectable		 3s3oA-5z73A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 235
HIS A 238
ASP A 174
LEU A 268
GLY A 297
 None
 1.25A 4pgfA-5z73A:
undetectable		 4pgfA-5z73A:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 5eeuA-5z73A:
undetectable
5eeuB-5z73A:
undetectable		 5eeuA-5z73A:
undetectable
5eeuB-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 5eeuD-5z73A:
undetectable
5eeuE-5z73A:
undetectable		 5eeuD-5z73A:
undetectable
5eeuE-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eeuE-5z73A:
undetectable
5eeuF-5z73A:
undetectable		 5eeuE-5z73A:
undetectable
5eeuF-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eeuJ-5z73A:
undetectable
5eeuK-5z73A:
undetectable		 5eeuJ-5z73A:
undetectable
5eeuK-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.20A 5eeuN-5z73A:
undetectable
5eeuO-5z73A:
undetectable		 5eeuN-5z73A:
undetectable
5eeuO-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5eeuP-5z73A:
undetectable
5eeuQ-5z73A:
undetectable		 5eeuP-5z73A:
undetectable
5eeuQ-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5eeuR-5z73A:
undetectable
5eeuS-5z73A:
undetectable		 5eeuR-5z73A:
undetectable
5eeuS-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5eeuS-5z73A:
undetectable
5eeuT-5z73A:
undetectable		 5eeuS-5z73A:
undetectable
5eeuT-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5eeuT-5z73A:
undetectable
5eeuU-5z73A:
undetectable		 5eeuT-5z73A:
undetectable
5eeuU-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.25A 5eeuU-5z73A:
undetectable
5eeuV-5z73A:
undetectable		 5eeuU-5z73A:
undetectable
5eeuV-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 5eevD-5z73A:
undetectable
5eevE-5z73A:
undetectable		 5eevD-5z73A:
undetectable
5eevE-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eevE-5z73A:
undetectable
5eevF-5z73A:
undetectable		 5eevE-5z73A:
undetectable
5eevF-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eevJ-5z73A:
undetectable
5eevK-5z73A:
undetectable		 5eevJ-5z73A:
undetectable
5eevK-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5eevN-5z73A:
undetectable
5eevO-5z73A:
undetectable		 5eevN-5z73A:
undetectable
5eevO-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5eevP-5z73A:
undetectable
5eevQ-5z73A:
undetectable		 5eevP-5z73A:
undetectable
5eevQ-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5eevR-5z73A:
undetectable
5eevS-5z73A:
undetectable		 5eevR-5z73A:
undetectable
5eevS-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5eevS-5z73A:
undetectable
5eevT-5z73A:
undetectable		 5eevS-5z73A:
undetectable
5eevT-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5eevT-5z73A:
undetectable
5eevU-5z73A:
undetectable		 5eevT-5z73A:
undetectable
5eevU-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.25A 5eevU-5z73A:
undetectable
5eevV-5z73A:
undetectable		 5eevU-5z73A:
undetectable
5eevV-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 5eewD-5z73A:
undetectable
5eewE-5z73A:
undetectable		 5eewD-5z73A:
undetectable
5eewE-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eewE-5z73A:
undetectable
5eewF-5z73A:
undetectable		 5eewE-5z73A:
undetectable
5eewF-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eewJ-5z73A:
undetectable
5eewK-5z73A:
undetectable		 5eewJ-5z73A:
undetectable
5eewK-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5eewN-5z73A:
undetectable
5eewO-5z73A:
undetectable		 5eewN-5z73A:
undetectable
5eewO-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5eewP-5z73A:
undetectable
5eewQ-5z73A:
undetectable		 5eewP-5z73A:
undetectable
5eewQ-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5eewR-5z73A:
undetectable
5eewS-5z73A:
undetectable		 5eewR-5z73A:
undetectable
5eewS-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5eewS-5z73A:
undetectable
5eewT-5z73A:
undetectable		 5eewS-5z73A:
undetectable
5eewT-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5eewT-5z73A:
undetectable
5eewU-5z73A:
undetectable		 5eewT-5z73A:
undetectable
5eewU-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.26A 5eewU-5z73A:
undetectable
5eewV-5z73A:
undetectable		 5eewU-5z73A:
undetectable
5eewV-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 5eexD-5z73A:
undetectable
5eexE-5z73A:
undetectable		 5eexD-5z73A:
undetectable
5eexE-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eexE-5z73A:
undetectable
5eexF-5z73A:
undetectable		 5eexE-5z73A:
undetectable
5eexF-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eexJ-5z73A:
undetectable
5eexK-5z73A:
undetectable		 5eexJ-5z73A:
undetectable
5eexK-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5eexN-5z73A:
undetectable
5eexO-5z73A:
undetectable		 5eexN-5z73A:
undetectable
5eexO-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5eexP-5z73A:
undetectable
5eexQ-5z73A:
undetectable		 5eexP-5z73A:
undetectable
5eexQ-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5eexQ-5z73A:
undetectable
5eexR-5z73A:
undetectable		 5eexQ-5z73A:
undetectable
5eexR-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5eexR-5z73A:
undetectable
5eexS-5z73A:
undetectable		 5eexR-5z73A:
undetectable
5eexS-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5eexS-5z73A:
undetectable
5eexT-5z73A:
undetectable		 5eexS-5z73A:
undetectable
5eexT-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5eexT-5z73A:
undetectable
5eexU-5z73A:
undetectable		 5eexT-5z73A:
undetectable
5eexU-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.26A 5eexU-5z73A:
undetectable
5eexV-5z73A:
undetectable		 5eexU-5z73A:
undetectable
5eexV-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 5eeyD-5z73A:
undetectable
5eeyE-5z73A:
undetectable		 5eeyD-5z73A:
undetectable
5eeyE-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eeyE-5z73A:
undetectable
5eeyF-5z73A:
undetectable		 5eeyE-5z73A:
undetectable
5eeyF-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eeyJ-5z73A:
undetectable
5eeyK-5z73A:
undetectable		 5eeyJ-5z73A:
undetectable
5eeyK-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.20A 5eeyN-5z73A:
undetectable
5eeyO-5z73A:
undetectable		 5eeyN-5z73A:
undetectable
5eeyO-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5eeyP-5z73A:
undetectable
5eeyQ-5z73A:
undetectable		 5eeyP-5z73A:
undetectable
5eeyQ-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5eeyQ-5z73A:
undetectable
5eeyR-5z73A:
undetectable		 5eeyQ-5z73A:
undetectable
5eeyR-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5eeyR-5z73A:
undetectable
5eeyS-5z73A:
undetectable		 5eeyR-5z73A:
undetectable
5eeyS-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5eeyS-5z73A:
undetectable
5eeyT-5z73A:
undetectable		 5eeyS-5z73A:
undetectable
5eeyT-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5eeyT-5z73A:
undetectable
5eeyU-5z73A:
undetectable		 5eeyT-5z73A:
undetectable
5eeyU-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.26A 5eeyU-5z73A:
undetectable
5eeyV-5z73A:
undetectable		 5eeyU-5z73A:
undetectable
5eeyV-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 5eezD-5z73A:
undetectable
5eezE-5z73A:
undetectable		 5eezD-5z73A:
undetectable
5eezE-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eezE-5z73A:
undetectable
5eezF-5z73A:
undetectable		 5eezE-5z73A:
undetectable
5eezF-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5eezJ-5z73A:
undetectable
5eezK-5z73A:
undetectable		 5eezJ-5z73A:
undetectable
5eezK-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.20A 5eezN-5z73A:
undetectable
5eezO-5z73A:
undetectable		 5eezN-5z73A:
undetectable
5eezO-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5eezP-5z73A:
undetectable
5eezQ-5z73A:
undetectable		 5eezP-5z73A:
undetectable
5eezQ-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5eezQ-5z73A:
undetectable
5eezR-5z73A:
undetectable		 5eezQ-5z73A:
undetectable
5eezR-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5eezR-5z73A:
undetectable
5eezS-5z73A:
undetectable		 5eezR-5z73A:
undetectable
5eezS-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5eezS-5z73A:
undetectable
5eezT-5z73A:
undetectable		 5eezS-5z73A:
undetectable
5eezT-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5eezT-5z73A:
undetectable
5eezU-5z73A:
undetectable		 5eezT-5z73A:
undetectable
5eezU-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.25A 5eezU-5z73A:
undetectable
5eezV-5z73A:
undetectable		 5eezU-5z73A:
undetectable
5eezV-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 5ef0D-5z73A:
undetectable
5ef0E-5z73A:
undetectable		 5ef0D-5z73A:
undetectable
5ef0E-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5ef0E-5z73A:
undetectable
5ef0F-5z73A:
undetectable		 5ef0E-5z73A:
undetectable
5ef0F-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5ef0J-5z73A:
undetectable
5ef0K-5z73A:
undetectable		 5ef0J-5z73A:
undetectable
5ef0K-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5ef0N-5z73A:
undetectable
5ef0O-5z73A:
undetectable		 5ef0N-5z73A:
undetectable
5ef0O-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5ef0P-5z73A:
undetectable
5ef0Q-5z73A:
undetectable		 5ef0P-5z73A:
undetectable
5ef0Q-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5ef0Q-5z73A:
undetectable
5ef0R-5z73A:
undetectable		 5ef0Q-5z73A:
undetectable
5ef0R-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5ef0R-5z73A:
undetectable
5ef0S-5z73A:
undetectable		 5ef0R-5z73A:
undetectable
5ef0S-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5ef0S-5z73A:
undetectable
5ef0T-5z73A:
undetectable		 5ef0S-5z73A:
undetectable
5ef0T-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5ef0T-5z73A:
undetectable
5ef0U-5z73A:
undetectable		 5ef0T-5z73A:
undetectable
5ef0U-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.26A 5ef0U-5z73A:
undetectable
5ef0V-5z73A:
undetectable		 5ef0U-5z73A:
undetectable
5ef0V-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 5ef1D-5z73A:
undetectable
5ef1E-5z73A:
undetectable		 5ef1D-5z73A:
undetectable
5ef1E-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5ef1E-5z73A:
undetectable
5ef1F-5z73A:
undetectable		 5ef1E-5z73A:
undetectable
5ef1F-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5ef1J-5z73A:
undetectable
5ef1K-5z73A:
undetectable		 5ef1J-5z73A:
undetectable
5ef1K-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.20A 5ef1N-5z73A:
undetectable
5ef1O-5z73A:
undetectable		 5ef1N-5z73A:
undetectable
5ef1O-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5ef1P-5z73A:
undetectable
5ef1Q-5z73A:
undetectable		 5ef1P-5z73A:
undetectable
5ef1Q-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5ef1Q-5z73A:
undetectable
5ef1R-5z73A:
undetectable		 5ef1Q-5z73A:
undetectable
5ef1R-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5ef1R-5z73A:
undetectable
5ef1S-5z73A:
undetectable		 5ef1R-5z73A:
undetectable
5ef1S-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5ef1S-5z73A:
undetectable
5ef1T-5z73A:
undetectable		 5ef1S-5z73A:
undetectable
5ef1T-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5ef1T-5z73A:
undetectable
5ef1U-5z73A:
undetectable		 5ef1T-5z73A:
undetectable
5ef1U-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.25A 5ef1U-5z73A:
undetectable
5ef1V-5z73A:
undetectable		 5ef1U-5z73A:
undetectable
5ef1V-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 5ef2D-5z73A:
undetectable
5ef2E-5z73A:
undetectable		 5ef2D-5z73A:
undetectable
5ef2E-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5ef2E-5z73A:
undetectable
5ef2F-5z73A:
undetectable		 5ef2E-5z73A:
undetectable
5ef2F-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5ef2J-5z73A:
undetectable
5ef2K-5z73A:
undetectable		 5ef2J-5z73A:
undetectable
5ef2K-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5ef2N-5z73A:
undetectable
5ef2O-5z73A:
undetectable		 5ef2N-5z73A:
undetectable
5ef2O-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5ef2P-5z73A:
undetectable
5ef2Q-5z73A:
undetectable		 5ef2P-5z73A:
undetectable
5ef2Q-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5ef2Q-5z73A:
undetectable
5ef2R-5z73A:
undetectable		 5ef2Q-5z73A:
undetectable
5ef2R-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5ef2R-5z73A:
undetectable
5ef2S-5z73A:
undetectable		 5ef2R-5z73A:
undetectable
5ef2S-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5ef2S-5z73A:
undetectable
5ef2T-5z73A:
undetectable		 5ef2S-5z73A:
undetectable
5ef2T-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5ef2T-5z73A:
undetectable
5ef2U-5z73A:
undetectable		 5ef2T-5z73A:
undetectable
5ef2U-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.25A 5ef2U-5z73A:
undetectable
5ef2V-5z73A:
undetectable		 5ef2U-5z73A:
undetectable
5ef2V-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.24A 5ef3D-5z73A:
undetectable
5ef3E-5z73A:
undetectable		 5ef3D-5z73A:
undetectable
5ef3E-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.22A 5ef3E-5z73A:
undetectable
5ef3F-5z73A:
undetectable		 5ef3E-5z73A:
undetectable
5ef3F-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 SER A  58
GLY A  34
ALA A  60
THR A  35
ILE A  71
 None
 1.23A 5ef3J-5z73A:
undetectable
5ef3K-5z73A:
undetectable		 5ef3J-5z73A:
undetectable
5ef3K-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.20A 5ef3N-5z73A:
undetectable
5ef3O-5z73A:
undetectable		 5ef3N-5z73A:
undetectable
5ef3O-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5ef3P-5z73A:
undetectable
5ef3Q-5z73A:
undetectable		 5ef3P-5z73A:
undetectable
5ef3Q-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5ef3Q-5z73A:
undetectable
5ef3R-5z73A:
undetectable		 5ef3Q-5z73A:
undetectable
5ef3R-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.21A 5ef3R-5z73A:
undetectable
5ef3S-5z73A:
undetectable		 5ef3R-5z73A:
undetectable
5ef3S-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.22A 5ef3S-5z73A:
undetectable
5ef3T-5z73A:
undetectable		 5ef3S-5z73A:
undetectable
5ef3T-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.23A 5ef3T-5z73A:
undetectable
5ef3U-5z73A:
undetectable		 5ef3T-5z73A:
undetectable
5ef3U-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 GLY A  34
ALA A  60
THR A  35
ILE A  71
SER A  58
 None
 1.25A 5ef3U-5z73A:
undetectable
5ef3V-5z73A:
undetectable		 5ef3U-5z73A:
undetectable
5ef3V-5z73A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 4 LEU A 424
TYR A 348
PRO A 368
ILE A 367
 None
 1.25A 5esgA-5z73A:
undetectable		 5esgA-5z73A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 9 GLN A 158
LEU A 216
ALA A 152
VAL A 143
ALA A 211
 None
 1.44A 5g44A-5z73A:
undetectable		 5g44A-5z73A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		3 / 3 TYR A 176
HIS A 238
PHE A 269
 None
 0.93A 6esmA-5z73A:
undetectable		 6esmA-5z73A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 5 ILE A 271
GLN A 241
THR A 303
LEU A 250
 None
 0.92A 6f3mD-5z73A:
undetectable		 6f3mD-5z73A:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5z73 ALR0819 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 6 GLY A 439
TRP A 382
ALA A 385
LEU A 384
 None
 1.03A 6fosA-5z73A:
2.0		 6fosA-5z73A:
17.28