SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5z7q FLAGELLIN
(Bacillus
cereus) 		4 / 7 LEU A  73
ASP A  77
LEU A  80
GLN A 207
 None
 0.86A 2qqcA-5z7qA:
undetectable
2qqcF-5z7qA:
undetectable		 2qqcA-5z7qA:
20.73
2qqcF-5z7qA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5z7q FLAGELLIN
(Bacillus
cereus) 		4 / 7 LEU A  73
ASP A  77
LEU A  80
GLN A 207
 None
 0.88A 2qqcG-5z7qA:
undetectable
2qqcJ-5z7qA:
undetectable		 2qqcG-5z7qA:
20.73
2qqcJ-5z7qA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5z7q FLAGELLIN
(Bacillus
cereus) 		6 / 12 LEU A 136
ILE A 197
THR A 166
PHE A 135
GLY A  76
GLY A  81
 None
 1.48A 4rzvA-5z7qA:
undetectable		 4rzvA-5z7qA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5z7q FLAGELLIN
(Bacillus
cereus) 		5 / 12 ILE A 164
PHE A 204
LEU A 208
THR A 128
LEU A 136
 None
 1.23A 5xxiA-5z7qA:
undetectable		 5xxiA-5z7qA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5z7q FLAGELLIN
(Bacillus
cereus) 		4 / 6 GLU A 200
LEU A 169
LEU A 136
LEU A  80
 None
 1.20A 5yvnA-5z7qA:
2.4		 5yvnA-5z7qA:
undetectable