SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z8l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RMT_D_ADND1504_1 (CLASS B ACID PHOSPHATASE)	5z8l	- (-)	4 / 8	PHE A 113 ASP A 158 THR A 112 TYR A 116	None	1.07A	1rmtD-5z8lA: undetectable	1rmtD-5z8lA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_A_ACTA502_0 (RNA POLYMERASE 3D-POL)	5z8l	- (-)	3 / 3	ARG A 16 LYS A 63 LYS A 65	None	1.16A	4k50A-5z8lA: undetectable	4k50A-5z8lA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_E_ACTE502_0 (RNA POLYMERASE 3D-POL)	5z8l	- (-)	3 / 3	ARG A 16 LYS A 63 LYS A 65	None	1.09A	4k50E-5z8lA: undetectable	4k50E-5z8lA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_I_ACTI506_0 (RNA POLYMERASE 3D-POL)	5z8l	- (-)	3 / 3	ARG A 16 LYS A 63 LYS A 65	None	1.13A	4k50I-5z8lA: undetectable	4k50I-5z8lA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	5z8l	- (-)	4 / 6	TYR A 49 PRO A 47 LEU A 38 GLU A 105	None	1.20A	4z4cA-5z8lA: undetectable	4z4cA-5z8lA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN5_E_LLLE301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	5z8l	- (-)	4 / 7	ASP A 158 TYR A 128 GLU A 89 GLU A 75	None	1.32A	6mn5E-5z8lA: undetectable	6mn5E-5z8lA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RMT_D_ADND1504_1","CLASS B ACID PHOSPHATASE","5z8l","-","-",4,"PHE A 113;ASP A 158;THR A 112;TYR A 116","None","1.07A","1rmtD-5z8lA:undetectable","1rmtD-5z8lA:undetectable"],["4K50_A_ACTA502_0","RNA POLYMERASE 3D-POL","5z8l","-","-",3,"ARG A  16;LYS A  63;LYS A  65","None","1.16A","4k50A-5z8lA:undetectable","4k50A-5z8lA:undetectable"],["4K50_E_ACTE502_0","RNA POLYMERASE 3D-POL","5z8l","-","-",3,"ARG A  16;LYS A  63;LYS A  65","None","1.09A","4k50E-5z8lA:undetectable","4k50E-5z8lA:undetectable"],["4K50_I_ACTI506_0","RNA POLYMERASE 3D-POL","5z8l","-","-",3,"ARG A  16;LYS A  63;LYS A  65","None","1.13A","4k50I-5z8lA:undetectable","4k50I-5z8lA:undetectable"],["4Z4C_A_IPHA904_0","PROTEIN ARGONAUTE-2","5z8l","-","-",4,"TYR A  49;PRO A  47;LEU A  38;GLU A 105","None","1.20A","4z4cA-5z8lA:undetectable","4z4cA-5z8lA:undetectable"],["6MN5_E_LLLE301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","5z8l","-","-",4,"ASP A 158;TYR A 128;GLU A  89;GLU A  75","None","1.32A","6mn5E-5z8lA:undetectable","6mn5E-5z8lA:undetectable"]]