SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z95'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 5z95 -
(-) 		5 / 10 LEU A 232
VAL A 224
VAL A 238
GLY A 225
LEU A 202
 None
GOL  A 304 ( 4.3A)
None
None
None
 1.42A 1fkoA-5z95A:
undetectable		 1fkoA-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 5z95 -
(-) 		5 / 11 LEU A 202
LEU A 232
PRO A 221
GLN A 213
MET A 117
 None
None
GOL  A 304 ( 4.9A)
None
None
 1.13A 2ft9A-5z95A:
undetectable		 2ft9A-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 5z95 -
(-) 		4 / 4 LEU A  47
THR A  11
ILE A   4
HIS A   8
 None
 1.39A 2jfaB-5z95A:
undetectable		 2jfaB-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 5z95 -
(-) 		5 / 12 ILE A  80
PHE A  62
ALA A   7
ILE A 185
ILE A 189
 None
 1.14A 2rlcA-5z95A:
undetectable		 2rlcA-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5z95 -
(-) 		4 / 8 ALA A  54
GLY A  55
THR A  56
THR A 177
 None
 0.78A 3rglA-5z95A:
undetectable		 3rglA-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5z95 -
(-) 		4 / 8 ARG A 176
THR A  56
VAL A  32
GLY A  27
 None
 0.89A 4eq4B-5z95A:
undetectable		 4eq4B-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 5z95 -
(-) 		4 / 6 ARG A 123
GLY A 132
ASP A 197
PRO A 122
 None
 1.02A 4lajA-5z95A:
undetectable
4lajB-5z95A:
undetectable		 4lajA-5z95A:
undetectable
4lajB-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 5z95 -
(-) 		3 / 3 MET A 219
MET A  99
TYR A  26
 EGC  A 301 (-3.8A)
None
EGC  A 301 ( 4.7A)
 1.40A 4p6xI-5z95A:
undetectable		 4p6xI-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 5z95 -
(-) 		5 / 12 VAL A 220
LEU A 198
VAL A 224
LEU A 228
SER A  98
 None
None
GOL  A 304 ( 4.3A)
None
None
 1.30A 4po0A-5z95A:
undetectable		 4po0A-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5z95 -
(-) 		4 / 7 ALA A 102
ARG A 229
GLY A 225
GLU A 226
 None
 0.71A 5bs8A-5z95A:
undetectable
5bs8B-5z95A:
3.1
5bs8C-5z95A:
undetectable		 5bs8A-5z95A:
undetectable
5bs8B-5z95A:
undetectable
5bs8C-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5z95 -
(-) 		4 / 7 ALA A 102
ARG A 229
GLY A 225
GLU A 226
 None
 0.65A 5btdA-5z95A:
undetectable
5btdB-5z95A:
3.0
5btdC-5z95A:
undetectable		 5btdA-5z95A:
undetectable
5btdB-5z95A:
undetectable
5btdC-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5z95 -
(-) 		4 / 7 ALA A 102
ARG A 229
GLY A 225
GLU A 226
 None
 0.69A 5btdA-5z95A:
undetectable
5btdC-5z95A:
undetectable
5btdD-5z95A:
3.3		 5btdA-5z95A:
undetectable
5btdC-5z95A:
undetectable
5btdD-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5z95 -
(-) 		4 / 6 ALA A 102
ARG A 229
GLY A 225
GLU A 226
 None
 0.69A 5btgA-5z95A:
undetectable
5btgB-5z95A:
3.1
5btgC-5z95A:
undetectable		 5btgA-5z95A:
undetectable
5btgB-5z95A:
undetectable
5btgC-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5z95 -
(-) 		4 / 5 SER A  98
ARG A 229
GLY A 225
GLU A 226
 None
 0.95A 5cdqA-5z95A:
undetectable
5cdqB-5z95A:
3.5
5cdqC-5z95A:
undetectable		 5cdqA-5z95A:
undetectable
5cdqB-5z95A:
undetectable
5cdqC-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5z95 -
(-) 		4 / 5 SER A  98
ARG A 229
GLY A 225
GLU A 226
 None
 0.95A 5cdqR-5z95A:
undetectable
5cdqS-5z95A:
3.0
5cdqT-5z95A:
undetectable		 5cdqR-5z95A:
undetectable
5cdqS-5z95A:
undetectable
5cdqT-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 5z95 -
(-) 		5 / 12 LEU A 261
VAL A  92
LEU A  13
LEU A  22
GLY A  93
 None
 1.18A 5ienA-5z95A:
undetectable		 5ienA-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 5z95 -
(-) 		3 / 3 CYH A  89
LYS A  88
HIS A 113
 None
 0.99A 5js5A-5z95A:
undetectable		 5js5A-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 5z95 -
(-) 		5 / 12 MET A 117
ALA A 100
SER A 105
LEU A 115
TYR A 227
 None
None
None
None
GOL  A 304 (-4.7A)
 1.24A 5vlmH-5z95A:
undetectable		 5vlmH-5z95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 5z95 -
(-) 		4 / 5 HIS A  51
ALA A 101
SER A  97
GLY A  23
 None
 1.28A 5yodD-5z95A:
undetectable		 5yodD-5z95A:
undetectable