SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z97'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5z97 LACTONASE FOR
PROTEIN
(Rhinocladiella
mackenziei) 		4 / 8 GLY A  80
ILE A 228
SER A 196
THR A 132
 None
 0.81A 2yoeB-5z97A:
undetectable
2yoeC-5z97A:
undetectable		 2yoeB-5z97A:
16.61
2yoeC-5z97A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 5z97 LACTONASE FOR
PROTEIN
(Rhinocladiella
mackenziei) 		4 / 8 VAL A 213
VAL A 227
PHE A 223
THR A 219
 None
 1.15A 3fhxB-5z97A:
undetectable		 3fhxB-5z97A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 5z97 LACTONASE FOR
PROTEIN
(Rhinocladiella
mackenziei) 		5 / 11 ARG A  81
GLN A  76
PRO A  62
TYR A 118
PRO A  33
 None
 1.46A 3ganA-5z97A:
undetectable		 3ganA-5z97A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA503_0
(OXIDOREDUCTASE,
FMN-BINDING)		 5z97 LACTONASE FOR
PROTEIN
(Rhinocladiella
mackenziei) 		4 / 6 SER A  67
TYR A  19
TRP A  18
PHE A  59
 None
 1.02A 4awuA-5z97A:
undetectable		 4awuA-5z97A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)		 5z97 LACTONASE FOR
PROTEIN
(Rhinocladiella
mackenziei) 		4 / 5 HIS A 128
ALA A 105
HIS A 243
TYR A 246
 None
ZER  A 301 (-3.0A)
ZER  A 301 (-4.0A)
None
 1.48A 4gboB-5z97A:
undetectable		 4gboB-5z97A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5z97 LACTONASE FOR
PROTEIN
(Rhinocladiella
mackenziei) 		4 / 7 GLU A  21
THR A  58
LEU A 170
SER A  47
 None
 1.09A 4pfjA-5z97A:
5.2		 4pfjA-5z97A:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5z97 LACTONASE FOR
PROTEIN
(Rhinocladiella
mackenziei) 		4 / 7 THR A  74
THR A  12
THR A  89
LEU A  90
 None
 0.94A 4z91F-5z97A:
undetectable
4z91G-5z97A:
undetectable
4z91H-5z97A:
undetectable
4z91I-5z97A:
undetectable
4z91J-5z97A:
undetectable		 4z91F-5z97A:
14.55
4z91G-5z97A:
14.55
4z91H-5z97A:
14.55
4z91I-5z97A:
14.55
4z91J-5z97A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 5z97 LACTONASE FOR
PROTEIN
(Rhinocladiella
mackenziei) 		4 / 6 GLY A  80
THR A 110
SER A 109
GLY A 107
 None
 0.85A 5k4pA-5z97A:
undetectable		 5k4pA-5z97A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 5z97 LACTONASE FOR
PROTEIN
(Rhinocladiella
mackenziei) 		5 / 10 PRO A 198
ALA A 229
GLY A 237
THR A 238
ILE A 236
 None
 1.23A 5vyhA-5z97A:
undetectable		 5vyhA-5z97A:
undetectable