SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5z9z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 5z9z SMALL RNA DEGRADING
NUCLEASE 1
(Arabidopsis
thaliana) 		5 / 12 ILE A 372
GLN A 333
ILE A 322
PRO A 323
LEU A 331
 None
 0.82A 1dlsA-5z9zA:
undetectable		 1dlsA-5z9zA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 5z9z SMALL RNA DEGRADING
NUCLEASE 1
(Arabidopsis
thaliana) 		5 / 12 ILE A 372
GLN A 333
ILE A 322
PRO A 323
LEU A 331
 None
 0.81A 1drfA-5z9zA:
undetectable		 1drfA-5z9zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 5z9z SMALL RNA DEGRADING
NUCLEASE 1
(Arabidopsis
thaliana) 		5 / 12 ILE A 372
GLN A 333
ILE A 322
PRO A 323
LEU A 331
 None
 0.81A 2w3mA-5z9zA:
undetectable		 2w3mA-5z9zA:
undetectable