SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 5zba -
(-) 		5 / 12 ALA B  16
ILE B 139
ILE B 135
PRO B  79
ALA B  78
 None
 0.95A 2nmyB-5zbaB:
undetectable		 2nmyB-5zbaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5zba -
(-) 		4 / 6 PRO B  85
SER B  47
GLU B  52
TYR B  53
 None
 1.36A 2x7hA-5zbaB:
undetectable		 2x7hA-5zbaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 5zba -
(-) 		5 / 10 ALA B  16
ILE B 139
ILE B 135
PRO B  79
ALA B  78
 None
 0.94A 3ekwA-5zbaB:
undetectable		 3ekwA-5zbaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5zba -
(-) 		4 / 5 LEU B  97
ARG B 137
ILE B  95
ILE B 139
 None
 0.98A 5dzk4-5zbaB:
undetectable
5dzkg-5zbaB:
undetectable
5dzkm-5zbaB:
undetectable
5dzkn-5zbaB:
undetectable		 5dzk4-5zbaB:
undetectable
5dzkg-5zbaB:
undetectable
5dzkm-5zbaB:
undetectable
5dzkn-5zbaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5zba -
(-) 		4 / 4 ILE B  95
ILE B 139
ARG B 137
LEU B  97
 None
 1.00A 5dzkh-5zbaB:
undetectable
5dzkn-5zbaB:
undetectable
5dzkv-5zbaB:
undetectable		 5dzkh-5zbaB:
undetectable
5dzkn-5zbaB:
undetectable
5dzkv-5zbaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5zba -
(-) 		3 / 3 LEU B  42
ASN B  13
LEU B  73
 None
 0.72A 6exiD-5zbaB:
undetectable		 6exiD-5zbaB:
undetectable