SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zbk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 106
LEU A  47
LEU A  31
CYH A   7
PHE A   9
 None
 1.50A 1a28A-5zbkA:
undetectable		 1a28A-5zbkA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 103
GLY A 133
LEU A 174
PHE A   9
 None
 1.13A 1gsfA-5zbkA:
undetectable		 1gsfA-5zbkA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 103
GLY A 133
LEU A 174
PHE A   9
 None
 1.13A 1gsfB-5zbkA:
undetectable		 1gsfB-5zbkA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 103
GLY A 133
LEU A 174
PHE A   9
 None
 1.13A 1gsfD-5zbkA:
undetectable		 1gsfD-5zbkA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 THR A 112
ALA A 115
GLU A 118
MET A  96
ILE A  66
 AMP  A 304 (-3.6A)
None
None
None
None
 0.95A 1qknA-5zbkA:
undetectable		 1qknA-5zbkA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 7 ASP A  53
GLY A  41
ILE A  65
THR A  37
 None
 0.70A 1t7iB-5zbkA:
undetectable		 1t7iB-5zbkA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 7 ASP A  53
GLY A  41
ILE A  65
THR A  37
 None
 0.72A 1t7jB-5zbkA:
undetectable		 1t7jB-5zbkA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 7 ILE A  65
ARG A  92
TYR A  40
GLU A  74
 None
AMP  A 304 (-3.9A)
None
AMP  A 304 (-2.5A)
 1.05A 2qebA-5zbkA:
undetectable		 2qebA-5zbkA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 7 ILE A  65
ARG A  92
TYR A  40
GLU A  74
 None
AMP  A 304 (-3.9A)
None
AMP  A 304 (-2.5A)
 1.09A 2qebB-5zbkA:
undetectable		 2qebB-5zbkA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  70
GLY A  43
GLY A  42
LEU A  38
ALA A  12
 AMP  A 304 (-4.2A)
None
None
None
AMP  A 304 (-3.4A)
 1.14A 3i5uB-5zbkA:
3.7		 3i5uB-5zbkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 178
TRP A 181
GLY A 163
 None
 0.77A 3l35A-5zbkA:
undetectable
3l35H-5zbkA:
undetectable		 3l35A-5zbkA:
undetectable
3l35H-5zbkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 178
TRP A 181
GLY A 163
 None
 0.80A 3l35B-5zbkA:
undetectable
3l35K-5zbkA:
undetectable		 3l35B-5zbkA:
undetectable
3l35K-5zbkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  43
GLY A  49
THR A  50
LEU A  47
LYS A  78
 None
 0.83A 3sglA-5zbkA:
undetectable		 3sglA-5zbkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 175
VAL A   8
LEU A  38
LEU A 178
LEU A  36
 None
 1.00A 4or0B-5zbkA:
undetectable		 4or0B-5zbkA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 135
GLY A 168
LEU A 174
LEU A 178
ALA A 177
 None
 1.03A 5dqfA-5zbkA:
undetectable		 5dqfA-5zbkA:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 165
VAL A 119
GLN A 124
GLU A 160
 None
 1.10A 5tudA-5zbkA:
undetectable		 5tudA-5zbkA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 132
GLN A 166
LEU A 116
PHE A 117
 None
 0.93A 5zcqC-5zbkA:
undetectable
5zcqJ-5zbkA:
undetectable		 5zcqC-5zbkA:
undetectable
5zcqJ-5zbkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 4 MET A  48
GLY A  49
HIS A  77
GLY A  43
 AMP  A 304 (-4.9A)
None
None
None
 1.49A 6fgdA-5zbkA:
2.5		 6fgdA-5zbkA:
undetectable