SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zbl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 5zbl CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Corynebacterium
glutamicum) 		5 / 11 ILE A 111
ALA A  30
LEU A  34
THR A  33
LEU A 182
 None
 1.03A 4g1bB-5zblA:
3.7		 4g1bB-5zblA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5zbl CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Corynebacterium
glutamicum) 		5 / 10 ALA A  31
THR A  28
ALA A  30
GLY A  18
THR A  17
 None
None
None
PO4  A 303 (-3.6A)
None
 1.04A 4qvyK-5zblA:
undetectable
4qvyL-5zblA:
undetectable		 4qvyK-5zblA:
18.87
4qvyL-5zblA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5zbl CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Corynebacterium
glutamicum) 		5 / 10 ALA A  31
THR A  28
ALA A  30
GLY A  18
THR A  17
 None
None
None
PO4  A 303 (-3.6A)
None
 1.04A 4qvyY-5zblA:
undetectable
4qvyZ-5zblA:
undetectable		 4qvyY-5zblA:
18.87
4qvyZ-5zblA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 5zbl CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Corynebacterium
glutamicum) 		3 / 3 VAL A 144
TYR A  27
ALA A  30
 None
 0.48A 4ybnA-5zblA:
undetectable		 4ybnA-5zblA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5zbl CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Corynebacterium
glutamicum) 		3 / 5 GLY A  18
GLY A 118
GLU A 122
 PO4  A 303 (-3.6A)
PO4  A 303 (-3.5A)
None
 0.49A 4z2eA-5zblA:
undetectable
4z2eD-5zblA:
undetectable		 4z2eA-5zblA:
10.68
4z2eD-5zblA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 5zbl CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Corynebacterium
glutamicum) 		4 / 5 LEU A 141
THR A  17
PRO A 178
ARG A  41
 None
 1.38A 6ew0B-5zblA:
undetectable		 6ew0B-5zblA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 5zbl CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Corynebacterium
glutamicum) 		4 / 5 LEU A 141
THR A  17
PRO A 178
ARG A  41
 None
 1.38A 6ew0D-5zblA:
undetectable		 6ew0D-5zblA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 5zbl CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Corynebacterium
glutamicum) 		4 / 5 LEU A 141
THR A  17
PRO A 178
ARG A  41
 None
 1.38A 6ew0H-5zblA:
undetectable		 6ew0H-5zblA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 5zbl CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Corynebacterium
glutamicum) 		4 / 5 LEU A 141
THR A  17
PRO A 178
ARG A  41
 None
 1.37A 6ew0I-5zblA:
undetectable		 6ew0I-5zblA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 5zbl CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Corynebacterium
glutamicum) 		4 / 4 MET A  55
GLY A  56
HIS A  84
GLY A  50
 None
 1.46A 6fgdA-5zblA:
3.1		 6fgdA-5zblA:
undetectable