SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zc2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 5zc2 -
(-) 		4 / 8 SER B  69
PHE B  74
ALA B  35
ARG B  42
 FMN  B 401 (-3.4A)
None
None
None
 1.11A 2bxkA-5zc2B:
2.2		 2bxkA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 5zc2 -
(-) 		5 / 12 LEU B 224
ALA B 221
THR B 218
GLN B 239
ILE B 249
 None
 1.26A 2jjpA-5zc2B:
undetectable		 2jjpA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y4N_B_PACB503_0
(PHENYLACETATE-COENZY
ME A LIGASE)		 5zc2 -
(-) 		4 / 4 SER B 214
GLY B 275
GLY B 260
LYS B 259
 None
 1.38A 2y4nB-5zc2B:
undetectable		 2y4nB-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5zc2 -
(-) 		4 / 7 SER B  68
PHE B  74
ILE B  64
GLY B  44
 FMN  B 401 (-2.2A)
None
FMN  B 401 (-4.4A)
None
 0.97A 2y7kA-5zc2B:
undetectable		 2y7kA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5zc2 -
(-) 		3 / 3 TYR B 269
GLU B 251
ASP B  15
 None
 0.86A 3bxoA-5zc2B:
undetectable		 3bxoA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5zc2 -
(-) 		4 / 7 ARG B 240
ILE B  90
GLN B 239
ASP B 237
 None
 1.07A 4w5oA-5zc2B:
undetectable		 4w5oA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5zc2 -
(-) 		4 / 6 ARG B 240
ILE B  90
GLN B 239
ASP B 237
 None
 1.06A 4w5qA-5zc2B:
undetectable		 4w5qA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5zc2 -
(-) 		4 / 6 ARG B 240
ILE B  90
GLN B 239
ASP B 237
 None
 1.06A 4w5tA-5zc2B:
undetectable		 4w5tA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5zc2 -
(-) 		4 / 6 ARG B 240
ILE B  90
GLN B 239
ASP B 237
 None
 1.08A 4z4cA-5zc2B:
undetectable		 4z4cA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5zc2 -
(-) 		4 / 6 ARG B 240
ILE B  90
GLN B 239
ASP B 237
 None
 1.03A 4z4dA-5zc2B:
undetectable		 4z4dA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5zc2 -
(-) 		4 / 7 ARG B 240
ILE B  90
GLN B 239
ASP B 237
 None
 1.02A 4z4eA-5zc2B:
undetectable		 4z4eA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5zc2 -
(-) 		4 / 7 ARG B 240
ILE B  90
GLN B 239
ASP B 237
 None
 1.05A 4z4gA-5zc2B:
undetectable		 4z4gA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 5zc2 -
(-) 		3 / 3 ASP B 138
ARG B  99
ARG B 247
 None
FMN  B 401 (-4.1A)
None
 0.90A 5eajB-5zc2B:
undetectable		 5eajB-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 5zc2 -
(-) 		4 / 6 LEU B  61
TRP B  62
ARG B 130
GLY B 144
 None
 0.93A 5o4yA-5zc2B:
undetectable		 5o4yA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 5zc2 -
(-) 		4 / 6 ARG B 240
ILE B  90
GLN B 239
ASP B 237
 None
 0.98A 6cbdA-5zc2B:
undetectable		 6cbdA-5zc2B:
undetectable