SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zc3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 5zc3 -
(-) 		4 / 7 THR B 432
SER B 431
TYR B 414
LEU B 410
 None
 0.87A 1ibgL-5zc3B:
undetectable		 1ibgL-5zc3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 5zc3 -
(-) 		3 / 3 TRP B 206
THR B 231
TYR B 232
 None
 0.80A 2a3aA-5zc3B:
undetectable		 2a3aA-5zc3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 5zc3 -
(-) 		3 / 3 TRP B 206
THR B 231
TYR B 232
 None
 0.77A 2a3aB-5zc3B:
undetectable		 2a3aB-5zc3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 5zc3 -
(-) 		3 / 3 TRP B 206
THR B 231
TYR B 232
 None
 0.81A 2a3bA-5zc3B:
undetectable		 2a3bA-5zc3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 5zc3 -
(-) 		4 / 5 GLN B 140
ILE B 133
LEU B 137
PHE B 141
 None
 1.27A 3ls4L-5zc3B:
undetectable		 3ls4L-5zc3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5zc3 -
(-) 		5 / 11 LEU B 419
ILE B 407
ALA B 436
ALA B 442
THR B 441
 None
 1.01A 3mdtB-5zc3B:
undetectable		 3mdtB-5zc3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5zc3 -
(-) 		5 / 10 VAL B 121
TRP B 117
VAL B  92
LEU B 166
LEU B 137
 None
 1.33A 4jtqA-5zc3B:
undetectable		 4jtqA-5zc3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5zc3 -
(-) 		4 / 5 TYR B 347
GLN B 351
SER B 317
ASP B 308
 None
 1.37A 4qtuB-5zc3B:
undetectable		 4qtuB-5zc3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5zc3 -
(-) 		4 / 5 GLY B 194
THR B 195
GLY B 178
LEU B 188
 None
 0.93A 5jlcA-5zc3B:
undetectable		 5jlcA-5zc3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5zc3 -
(-) 		4 / 4 GLN B 479
GLN B 440
PRO B 472
ALA B 420
 None
 1.44A 5odcA-5zc3B:
undetectable
5odcG-5zc3B:
undetectable		 5odcA-5zc3B:
undetectable
5odcG-5zc3B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_G_ACTG704_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5zc3 -
(-) 		4 / 5 PRO B 472
ALA B 420
GLN B 479
GLN B 440
 None
 1.44A 5odcA-5zc3B:
undetectable
5odcG-5zc3B:
undetectable		 5odcA-5zc3B:
undetectable
5odcG-5zc3B:
undetectable