SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zct'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 5zct -
(-) 		3 / 3 ALA A 245
VAL A 193
TRP A 285
 None
 0.93A 1gmkC-5zctA:
undetectable
1gmkD-5zctA:
undetectable		 1gmkC-5zctA:
undetectable
1gmkD-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 5zct -
(-) 		5 / 11 ILE A 270
LEU A 191
GLY A 194
ILE A 286
VAL A 198
 None
 1.11A 2fxdA-5zctA:
undetectable		 2fxdA-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 5zct -
(-) 		5 / 12 ALA A  97
LEU A 242
ALA A 237
VAL A 258
GLN A 177
 None
None
None
None
ANP  A 401 (-3.7A)
 1.09A 2ve3A-5zctA:
undetectable		 2ve3A-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5zct -
(-) 		4 / 7 SER A  14
CYH A  15
ILE A   5
SER A 264
 None
 1.08A 2xz5A-5zctA:
undetectable
2xz5B-5zctA:
undetectable		 2xz5A-5zctA:
undetectable
2xz5B-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5zct -
(-) 		4 / 8 GLY A 246
ASP A 248
ILE A 249
VAL A 197
 None
 0.72A 3fi0G-5zctA:
undetectable		 3fi0G-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5zct -
(-) 		4 / 8 GLY A 246
ASP A 248
ILE A 249
VAL A 197
 None
 0.75A 3fi0Q-5zctA:
undetectable		 3fi0Q-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5zct -
(-) 		4 / 7 ALA A  95
ILE A  94
ARG A  78
GLY A  73
 None
 0.94A 3v4tH-5zctA:
undetectable		 3v4tH-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5zct -
(-) 		4 / 8 ILE A 276
ASP A 277
ILE A 278
GLY A 266
 None
 0.80A 4acbC-5zctA:
4.6		 4acbC-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5zct -
(-) 		5 / 12 VAL A 197
ILE A 270
VAL A 261
ALA A 245
LEU A 267
 None
 1.40A 4m11C-5zctA:
undetectable		 4m11C-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 5zct -
(-) 		5 / 9 VAL A 244
LEU A  77
LEU A  18
LEU A   6
ILE A   5
 None
 1.31A 4ubsA-5zctA:
undetectable		 4ubsA-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5zct -
(-) 		4 / 6 VAL A 198
LEU A 242
ARG A  64
ILE A  94
 None
 0.97A 5jw1A-5zctA:
undetectable		 5jw1A-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5zct -
(-) 		5 / 12 ALA A   4
GLY A  10
LYS A   2
ASP A  59
ALA A  60
 None
 1.35A 5zvgA-5zctA:
2.2		 5zvgA-5zctA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5zct -
(-) 		5 / 12 ALA A   4
GLY A  10
LYS A   2
ASP A  59
ALA A  60
 None
 1.33A 5zvgB-5zctA:
2.3		 5zvgB-5zctA:
undetectable