SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zdh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5zdh TYPE II SECRETION
SYSTEM LIPOPROTEIN
(Escherichia
coli) 		5 / 12 THR P  88
TYR P  65
PHE P  61
LEU P  23
VAL P  33
 None
 1.25A 1q23B-5zdhP:
undetectable		 1q23B-5zdhP:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5zdh TYPE II SECRETION
SYSTEM LIPOPROTEIN
(Escherichia
coli) 		5 / 12 THR P  88
TYR P  65
PHE P  61
LEU P  23
VAL P  33
 None
 1.28A 1q23C-5zdhP:
undetectable		 1q23C-5zdhP:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5zdh TYPE II SECRETION
SYSTEM LIPOPROTEIN
(Escherichia
coli) 		5 / 11 THR P  88
TYR P  65
PHE P  61
LEU P  23
VAL P  33
 None
 1.29A 1q23F-5zdhP:
undetectable		 1q23F-5zdhP:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5zdh TYPE II SECRETION
SYSTEM LIPOPROTEIN
(Escherichia
coli) 		5 / 11 THR P  88
TYR P  65
PHE P  61
LEU P  23
VAL P  33
 None
 1.34A 1q23I-5zdhP:
undetectable		 1q23I-5zdhP:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5zdh TYPE II SECRETION
SYSTEM LIPOPROTEIN
(Escherichia
coli) 		5 / 11 THR P  88
TYR P  65
PHE P  61
LEU P  23
VAL P  33
 None
 1.28A 1q23L-5zdhP:
undetectable		 1q23L-5zdhP:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 5zdh TYPE II SECRETION
SYSTEM PROTEIN D
(Escherichia
coli) 		4 / 6 ARG A 111
ILE A 143
LEU A 122
GLU A 117
 None
 1.04A 2ya7A-5zdhA:
undetectable		 2ya7A-5zdhA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 5zdh TYPE II SECRETION
SYSTEM PROTEIN D
(Escherichia
coli) 		4 / 6 ARG A 111
ILE A 143
LEU A 122
GLU A 117
 None
 1.02A 2ya7D-5zdhA:
undetectable		 2ya7D-5zdhA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 5zdh TYPE II SECRETION
SYSTEM PROTEIN D
(Escherichia
coli) 		5 / 9 LEU A 400
ILE A 369
GLY A 366
SER A 398
LEU A 397
 None
 1.13A 3ai9X-5zdhA:
undetectable		 3ai9X-5zdhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5zdh TYPE II SECRETION
SYSTEM PROTEIN D
(Escherichia
coli) 		4 / 7 LEU A 522
PRO A 438
SER A 436
VAL A 325
 None
 1.12A 4klrA-5zdhA:
undetectable		 4klrA-5zdhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 5zdh TYPE II SECRETION
SYSTEM PROTEIN D
(Escherichia
coli) 		3 / 3 ILE A 557
PRO A 558
ILE A 560
 None
 0.45A 5hw8F-5zdhA:
undetectable		 5hw8F-5zdhA:
21.14