SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ze4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 LEU A 259
LEU A 255
SER A  57
GLY A 132
 None
 0.75A 1a4lC-5ze4A:
2.2		 1a4lC-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 THR A 520
LEU A 402
GLY A 400
LEU A 398
 None
 1.00A 1gtiE-5ze4A:
undetectable		 1gtiE-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 4 LEU A 274
PRO A 271
LEU A 303
ARG A 299
 None
 1.41A 1hrkB-5ze4A:
5.4		 1hrkB-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 ASP A 309
LEU A 303
LEU A 305
 None
 0.50A 1ikeA-5ze4A:
undetectable		 1ikeA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 THR A 216
GLY A 286
VAL A 281
HIS A 499
ARG A 487
 MG  A 606 ( 4.7A)
None
None
None
None
 1.35A 1jdvE-5ze4A:
4.9
1jdvF-5ze4A:
3.4		 1jdvE-5ze4A:
undetectable
1jdvF-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 TRP A 129
TYR A 130
LEU A 153
 None
 0.87A 1kxhA-5ze4A:
undetectable		 1kxhA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 ASP A 309
LEU A 303
LEU A 305
 None
 0.48A 1np1B-5ze4A:
undetectable		 1np1B-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 ILE A  26
LEU A  39
PHE A  89
GLY A  88
 None
 0.92A 1os6A-5ze4A:
undetectable		 1os6A-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLN A 505
ALA A 566
GLY A 460
GLY A 454
LEU A 556
 None
 1.08A 1rjdA-5ze4A:
undetectable		 1rjdA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 258
LEU A 255
ALA A  84
VAL A  77
LEU A 231
 None
 1.12A 1s9pA-5ze4A:
undetectable		 1s9pA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 4 LEU A 274
PRO A 271
LEU A 303
ARG A 299
 None
 1.41A 2pnjB-5ze4A:
2.3		 2pnjB-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ILE A 121
GLY A  55
ILE A  54
VAL A 160
ILE A 136
 None
 1.13A 2r5qA-5ze4A:
undetectable		 2r5qA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 9 ILE A 121
GLY A  55
ILE A  54
VAL A 160
ILE A 136
 None
 1.13A 2r5qC-5ze4A:
undetectable		 2r5qC-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 VAL A 496
ILE A 523
GLY A 524
ARG A 527
 None
 0.86A 3bjwB-5ze4A:
undetectable		 3bjwB-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 VAL A 496
ILE A 523
GLY A 524
ARG A 527
 None
 0.91A 3bjwF-5ze4A:
undetectable		 3bjwF-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 VAL A 496
ILE A 523
GLY A 524
ARG A 527
 None
 0.87A 3bjwH-5ze4A:
undetectable		 3bjwH-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ALA A 481
ILE A 528
ILE A 510
PRO A 509
ILE A 450
 None
 1.23A 3clbB-5ze4A:
2.0		 3clbB-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		6 / 12 MET A 220
THR A 216
ALA A 296
TYR A 161
VAL A 563
THR A 572
 None
MG  A 606 ( 4.7A)
None
None
None
None
 1.40A 3dl9A-5ze4A:
undetectable		 3dl9A-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 ILE A 117
MET A 159
ILE A 147
HIS A 293
 None
 0.94A 3eteA-5ze4A:
2.6
3eteE-5ze4A:
2.6		 3eteA-5ze4A:
undetectable
3eteE-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 ILE A 117
MET A 159
ILE A 147
HIS A 293
 None
 0.95A 3eteB-5ze4A:
2.6
3eteC-5ze4A:
3.5		 3eteB-5ze4A:
undetectable
3eteC-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 MET A 159
ILE A 147
HIS A 293
ILE A 117
 None
 0.96A 3eteD-5ze4A:
2.7
3eteF-5ze4A:
3.4		 3eteD-5ze4A:
undetectable
3eteF-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 LEU A 347
SER A 235
GLY A 286
MET A 214
 None
 1.02A 3hcnA-5ze4A:
3.9		 3hcnA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 CYH A  66
PRO A 137
ASP A 140
 FES  A 601 (-2.3A)
None
MG  A 606 ( 3.0A)
 1.01A 3hlwB-5ze4A:
undetectable		 3hlwB-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 GLU A 503
GLU A 506
TRP A 544
 None
 1.31A 3hrdA-5ze4A:
0.4
3hrdE-5ze4A:
undetectable
3hrdF-5ze4A:
undetectable		 3hrdA-5ze4A:
undetectable
3hrdE-5ze4A:
undetectable
3hrdF-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 ASP A   8
ARG A 152
ALA A   7
 None
 0.62A 3mbgC-5ze4A:
undetectable		 3mbgC-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 ARG A 487
VAL A 281
THR A 219
 None
 0.79A 3ndtA-5ze4A:
undetectable		 3ndtA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 ILE A 158
SER A  57
ILE A  56
VAL A  77
VAL A  81
 None
 1.37A 3rf4A-5ze4A:
undetectable
3rf4B-5ze4A:
undetectable		 3rf4A-5ze4A:
undetectable
3rf4B-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 ILE A  26
LEU A  39
PHE A  89
GLY A  88
 None
 0.91A 3sj1X-5ze4A:
undetectable		 3sj1X-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 TYR A 559
SER A 110
ASP A 568
ILE A 295
 None
 1.28A 3uj7B-5ze4A:
undetectable		 3uj7B-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 ARG A 152
GLU A 574
THR A 572
 None
 0.80A 3v4tA-5ze4A:
undetectable		 3v4tA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 ALA A 296
ILE A 297
ARG A 152
GLY A 145
 None
 0.89A 3v4tH-5ze4A:
undetectable		 3v4tH-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE A 100
SER A 113
LEU A 116
VAL A 555
LEU A 556
 None
 0.91A 3w67B-5ze4A:
undetectable		 3w67B-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 11 ILE A 521
ASP A 522
ILE A 523
GLY A 524
GLY A 413
 None
 1.08A 4ac9B-5ze4A:
5.9
4ac9C-5ze4A:
6.2		 4ac9B-5ze4A:
undetectable
4ac9C-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 ILE A  26
LEU A  39
PHE A  89
GLY A  88
 None
 0.92A 4hbfA-5ze4A:
undetectable		 4hbfA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 7 ILE A  26
LEU A  39
PHE A  89
GLY A  88
 None
 0.93A 4hc3A-5ze4A:
undetectable		 4hc3A-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 5 TYR A 559
GLY A 569
ASP A 568
GLU A 503
 None
 1.16A 4nkvD-5ze4A:
undetectable		 4nkvD-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 MET A 102
ILE A  94
ILE A 117
VAL A  59
 None
 0.91A 4olmA-5ze4A:
undetectable		 4olmA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 CYH A  66
PRO A 137
ASP A 140
 FES  A 601 (-2.3A)
None
MG  A 606 ( 3.0A)
 1.01A 4pm5A-5ze4A:
undetectable		 4pm5A-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 PHE A 488
SER A 469
PRO A 467
LEU A 465
 None
 1.26A 5dzka-5ze4A:
2.4
5dzko-5ze4A:
undetectable		 5dzka-5ze4A:
undetectable
5dzko-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE A 121
GLY A 157
ILE A 158
ARG A 114
ALA A 221
 None
 1.03A 5e72A-5ze4A:
undetectable		 5e72A-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ARG A 487
VAL A 408
VAL A 291
GLY A 569
THR A 572
 None
 1.19A 5x24A-5ze4A:
undetectable		 5x24A-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 SER A 567
ARG A 527
ASP A 529
ASP A 405
 None
 1.13A 5zw4A-5ze4A:
undetectable		 5zw4A-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLY A 516
ALA A 423
VAL A 449
LEU A 483
VAL A 425
 None
 0.87A 6dh0B-5ze4A:
undetectable		 6dh0B-5ze4A:
undetectable