SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zhg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7H_C_SAMC530_1 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	5zhg	OUTER CAPSID PROTEIN VP8* (Rotavirus C)	3 / 3	TYR A 153 GLU A 50 ASN A 66	None	1.00A	2y7hC-5zhgA: undetectable	2y7hC-5zhgA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CLD_B_GW6B2_2 (GLUCOCORTICOID RECEPTOR)	5zhg	OUTER CAPSID PROTEIN VP8* (Rotavirus C)	4 / 8	MET A 152 LEU A 34 GLN A 26 ILE A 2	None	0.78A	3cldB-5zhgA: undetectable	3cldB-5zhgA: 15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TQB_A_FOLA2001_0 (DIHYDROFOLATE REDUCTASE)	5zhg	OUTER CAPSID PROTEIN VP8* (Rotavirus C)	5 / 11	LEU A 51 THR A 21 ILE A 109 ILE A 11 THR A 154	None	1.04A	3tqbA-5zhgA: undetectable	3tqbA-5zhgA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PTJ_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	5zhg	OUTER CAPSID PROTEIN VP8* (Rotavirus C)	5 / 12	LEU A 51 THR A 21 ILE A 109 ILE A 11 THR A 154	None	1.16A	4ptjA-5zhgA: undetectable	4ptjA-5zhgA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IWU_A_ERYA404_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	5zhg	OUTER CAPSID PROTEIN VP8* (Rotavirus C)	5 / 12	ILE A 150 HIS A 37 PHE A 141 SER A 114 ILE A 17	None	1.35A	5iwuA-5zhgA: 1.4	5iwuA-5zhgA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Y7H_C_SAMC530_1","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","5zhg","OUTER CAPSID PROTEIN VP8*","Rotavirus C",3,"TYR A 153;GLU A  50;ASN A  66","None","1.00A","2y7hC-5zhgA:undetectable","2y7hC-5zhgA:undetectable"],["3CLD_B_GW6B2_2","GLUCOCORTICOID RECEPTOR","5zhg","OUTER CAPSID PROTEIN VP8*","Rotavirus C",4,"MET A 152;LEU A  34;GLN A  26;ILE A   2","None","0.78A","3cldB-5zhgA:undetectable","3cldB-5zhgA:15.94"],["3TQB_A_FOLA2001_0","DIHYDROFOLATE REDUCTASE","5zhg","OUTER CAPSID PROTEIN VP8*","Rotavirus C",5,"LEU A  51;THR A  21;ILE A 109;ILE A  11;THR A 154","None","1.04A","3tqbA-5zhgA:undetectable","3tqbA-5zhgA:undetectable"],["4PTJ_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","5zhg","OUTER CAPSID PROTEIN VP8*","Rotavirus C",5,"LEU A  51;THR A  21;ILE A 109;ILE A  11;THR A 154","None","1.16A","4ptjA-5zhgA:undetectable","4ptjA-5zhgA:undetectable"],["5IWU_A_ERYA404_0","MACROLIDE 2'-PHOSPHOTRANSFERASE II","5zhg","OUTER CAPSID PROTEIN VP8*","Rotavirus C",5,"ILE A 150;HIS A  37;PHE A 141;SER A 114;ILE A  17","None","1.35A","5iwuA-5zhgA:1.4","5iwuA-5zhgA:undetectable"]]