SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zi9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 5zi9 CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Streptomyces
coelicolor) 		4 / 6 LEU A  55
ILE A  57
ASP A  50
PRO A  51
 None
 1.22A 1ditH-5zi9A:
undetectable
1ditP-5zi9A:
undetectable		 1ditH-5zi9A:
13.13
1ditP-5zi9A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 5zi9 CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Streptomyces
coelicolor) 		5 / 12 ALA A 167
PHE A 170
PHE A 198
LEU A 151
LEU A  68
 None
 1.11A 1dtlA-5zi9A:
undetectable		 1dtlA-5zi9A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5zi9 CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Streptomyces
coelicolor) 		4 / 8 ASN A 144
GLY A 111
PHE A 163
ILE A 108
 None
 0.89A 4fglD-5zi9A:
5.3		 4fglD-5zi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5zi9 CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Streptomyces
coelicolor) 		5 / 12 ASN A 144
SER A 130
GLY A  64
ASN A 152
PHE A 153
 None
 1.20A 4obwA-5zi9A:
undetectable		 4obwA-5zi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 5zi9 CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Streptomyces
coelicolor) 		5 / 12 ASN A 144
GLY A  97
ALA A 123
TYR A  90
GLU A 117
 None
 1.20A 4xt8A-5zi9A:
undetectable		 4xt8A-5zi9A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y28_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 5zi9 CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Streptomyces
coelicolor) 		5 / 9 ARG A  95
ALA A  92
LEU A  96
GLY A  97
PHE A 184
 None
 1.23A 4y28A-5zi9A:
undetectable
4y28J-5zi9A:
undetectable		 4y28A-5zi9A:
6.98
4y28J-5zi9A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 5zi9 CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Streptomyces
coelicolor) 		4 / 8 LEU A 215
PHE A 184
LEU A 202
ILE A 200
 None
 0.74A 5mzjA-5zi9A:
undetectable		 5mzjA-5zi9A:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5zi9 CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Streptomyces
coelicolor) 		5 / 12 GLY A  97
VAL A 239
VAL A 243
PHE A 203
ALA A 115
 None
 1.22A 5n0wA-5zi9A:
2.5		 5n0wA-5zi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 5zi9 CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE
(Streptomyces
coelicolor) 		5 / 12 GLU A 117
THR A  83
GLU A  89
THR A 179
GLY A 176
 None
None
None
FLC  A 502 ( 3.8A)
FLC  A 502 (-3.4A)
 1.26A 5xipC-5zi9A:
3.3		 5xipC-5zi9A:
undetectable