SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zj5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 5zj5 -
(-) 		3 / 3 ASP A  50
LYS A  54
ARG A  59
 None
 1.05A 1ra8A-5zj5A:
undetectable		 1ra8A-5zj5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5zj5 -
(-) 		4 / 7 ARG A  81
SER A 121
GLN A 162
GLU A 164
 NAI  A 301 (-2.7A)
NAI  A 301 (-2.7A)
GDP  A 302 ( 3.2A)
NAI  A 301 (-3.5A)
 0.57A 2c8aA-5zj5A:
3.0		 2c8aA-5zj5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 5zj5 -
(-) 		4 / 7 SER A 121
SER A 123
GLN A 162
GLU A 164
 NAI  A 301 (-2.7A)
None
GDP  A 302 ( 3.2A)
NAI  A 301 (-3.5A)
 0.65A 2c8aA-5zj5A:
3.0		 2c8aA-5zj5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 5zj5 -
(-) 		4 / 5 GLY A 169
VAL A  61
PRO A 118
TYR A 110
 None
None
None
NAI  A 301 (-4.4A)
 1.09A 4grkA-5zj5A:
undetectable		 4grkA-5zj5A:
undetectable