SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5zmy -
(-) 		5 / 12 ALA A 256
ALA A 255
LEU A 251
PHE A 252
LEU A  28
 None
 0.88A 1fm9A-5zmyA:
undetectable		 1fm9A-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 5zmy -
(-) 		3 / 3 ALA A  54
VAL A  44
TRP A  46
 None
 1.02A 1gmkA-5zmyA:
undetectable
1gmkB-5zmyA:
undetectable		 1gmkA-5zmyA:
undetectable
1gmkB-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 5zmy -
(-) 		3 / 3 ALA A  54
VAL A  44
TRP A  46
 None
 1.01A 1gmkC-5zmyA:
undetectable
1gmkD-5zmyA:
undetectable		 1gmkC-5zmyA:
undetectable
1gmkD-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5zmy -
(-) 		5 / 12 ALA A 256
ALA A 255
LEU A 251
PHE A 252
LEU A  28
 None
 0.90A 1k74A-5zmyA:
undetectable		 1k74A-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 5zmy -
(-) 		3 / 3 GLU A  34
HIS A  67
HIS A  69
 ZN  A 400 ( 2.3A)
TAR  A 401 ( 3.3A)
ZN  A 400 ( 3.3A)
 0.32A 1oe2A-5zmyA:
undetectable		 1oe2A-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 5zmy -
(-) 		5 / 12 ALA A 256
ALA A 255
LEU A 251
PHE A 252
LEU A  28
 None
 0.96A 1xiuB-5zmyA:
undetectable		 1xiuB-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5zmy -
(-) 		5 / 12 ALA A 256
ALA A 255
LEU A 251
PHE A 252
LEU A  28
 None
 0.95A 1xlsA-5zmyA:
undetectable		 1xlsA-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5zmy -
(-) 		5 / 12 ALA A 256
ALA A 255
LEU A 251
PHE A 252
LEU A  28
 None
 0.95A 1xlsB-5zmyA:
undetectable		 1xlsB-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5zmy -
(-) 		5 / 12 ALA A 256
ALA A 255
LEU A 251
PHE A 252
LEU A  28
 None
 0.95A 1xlsC-5zmyA:
undetectable		 1xlsC-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 5zmy -
(-) 		3 / 3 THR A 189
PRO A 187
THR A 191
 None
 0.77A 209dC-5zmyA:
undetectable		 209dC-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 5zmy -
(-) 		4 / 8 TYR A 158
HIS A  69
GLU A  34
HIS A  67
 None
ZN  A 400 ( 3.3A)
ZN  A 400 ( 2.3A)
TAR  A 401 ( 3.3A)
 0.78A 2bnnA-5zmyA:
undetectable
2bnnB-5zmyA:
undetectable		 2bnnA-5zmyA:
undetectable
2bnnB-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BMC_C_FOLC270_0
(PTERIDINE REDUCTASE)		 5zmy -
(-) 		5 / 12 ARG A  92
PRO A 179
LEU A 121
PRO A 129
GLU A 119
 None
 1.23A 3bmcC-5zmyA:
2.0		 3bmcC-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 5zmy -
(-) 		5 / 11 ALA A  73
ARG A  71
ILE A  51
PRO A  48
ARG A  38
 None
 1.44A 3bpxA-5zmyA:
undetectable
3bpxB-5zmyA:
undetectable		 3bpxA-5zmyA:
undetectable
3bpxB-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5zmy -
(-) 		5 / 12 ASN A 250
GLY A 249
ARG A  39
THR A 288
PHE A 252
 None
 1.49A 3cldA-5zmyA:
undetectable		 3cldA-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 5zmy -
(-) 		5 / 12 VAL A 285
TYR A 272
PHE A 252
LEU A 251
GLU A  34
 None
None
None
None
ZN  A 400 ( 2.3A)
 1.23A 3medA-5zmyA:
undetectable
3medB-5zmyA:
undetectable		 3medA-5zmyA:
undetectable
3medB-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 5zmy -
(-) 		5 / 9 ILE A  91
THR A 281
LEU A  28
GLU A  29
GLY A 270
 None
 1.09A 3nxuB-5zmyA:
undetectable		 3nxuB-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 5zmy -
(-) 		4 / 6 THR A 306
ILE A  32
ASP A 130
THR A 302
 None
 1.10A 3q70A-5zmyA:
undetectable		 3q70A-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5zmy -
(-) 		4 / 8 TYR A  35
HIS A  67
TYR A  84
LEU A 103
 None
TAR  A 401 ( 3.3A)
None
None
 1.39A 3uzzB-5zmyA:
10.0		 3uzzB-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 5zmy -
(-) 		4 / 5 GLY A 137
TRP A 184
ALA A 135
PHE A 209
 None
TAR  A 401 (-4.7A)
None
None
 1.28A 3wqwA-5zmyA:
6.1		 3wqwA-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 5zmy -
(-) 		5 / 12 LEU A 136
PRO A 179
ASP A 197
MET A 196
GLY A 199
 None
 1.48A 4j7xA-5zmyA:
2.1		 4j7xA-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5zmy -
(-) 		5 / 9 LEU A 234
LEU A 227
PHE A 209
THR A 189
LEU A 192
 None
 1.39A 4ltwA-5zmyA:
undetectable		 4ltwA-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5zmy -
(-) 		5 / 12 PRO A 133
HIS A  69
LEU A 103
GLY A 218
THR A 212
 TAR  A 401 (-4.3A)
ZN  A 400 ( 3.3A)
None
None
None
 1.42A 4mubA-5zmyA:
undetectable		 4mubA-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5zmy -
(-) 		5 / 12 ALA A 256
ALA A 255
LEU A 251
PHE A 252
LEU A  28
 None
 1.01A 6a60D-5zmyA:
undetectable		 6a60D-5zmyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5zmy -
(-) 		3 / 3 ARG A 173
LYS A 178
ARG A  31
 None
None
TAR  A 401 (-3.2A)
 1.25A 6c06D-5zmyA:
undetectable		 6c06D-5zmyA:
undetectable