SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)
5zov -
(-)
4 / 8 ASP A 314
HIS A 194
HIS A 135
ILE A 358
ASC  A 501 (-2.7A)
ASC  A 501 (-4.0A)
ASC  A 501 (-4.0A)
ASC  A 501 ( 4.9A)
0.98A 1ei6C-5zovA:
undetectable
1ei6C-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)
5zov -
(-)
6 / 12 LEU A 165
THR A 162
ALA A 163
LEU A 114
ILE A 172
GLY A 171
None
1.44A 1qknA-5zovA:
undetectable
1qknA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
5zov -
(-)
4 / 7 LEU A  62
PHE A 244
MET A 240
MET A 360
None
0.99A 1wrlA-5zovA:
undetectable
1wrlB-5zovA:
undetectable
1wrlA-5zovA:
undetectable
1wrlB-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)
5zov -
(-)
5 / 11 SER A 295
THR A 133
GLY A 134
HIS A 135
GLN A 139
None
None
None
ASC  A 501 (-4.0A)
ASC  A 501 (-3.1A)
1.45A 2hmaA-5zovA:
undetectable
2hmaA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)
5zov -
(-)
5 / 9 PHE A 347
SER A 349
ALA A 340
LEU A 343
GLY A 346
None
1.07A 2wscA-5zovA:
3.6
2wscA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)
5zov -
(-)
5 / 9 PHE A 347
SER A 349
ALA A 340
LEU A 343
GLY A 346
None
1.06A 2wseA-5zovA:
2.6
2wseA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)
5zov -
(-)
5 / 9 PHE A 347
SER A 349
ALA A 340
LEU A 343
GLY A 346
None
1.07A 2wsfA-5zovA:
2.2
2wsfA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)
5zov -
(-)
5 / 12 PHE A 370
PRO A 180
ALA A 183
ALA A 416
MET A 177
None
1.26A 2x2nA-5zovA:
undetectable
2x2nA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)
5zov -
(-)
5 / 12 PHE A 370
PRO A 180
ALA A 183
ALA A 416
MET A 177
None
1.27A 2x2nB-5zovA:
undetectable
2x2nB-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)
5zov -
(-)
5 / 12 PHE A 370
PRO A 180
VAL A 184
ALA A 416
MET A 177
None
1.35A 2x2nC-5zovA:
undetectable
2x2nC-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)
5zov -
(-)
5 / 7 PHE A  52
GLY A  51
PHE A 290
MET A  90
PHE A 138
None
1.34A 3ko0D-5zovA:
undetectable
3ko0E-5zovA:
0.8
3ko0D-5zovA:
undetectable
3ko0E-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)
5zov -
(-)
5 / 9 PHE A 347
SER A 349
ALA A 340
LEU A 343
GLY A 346
None
1.08A 3lw5A-5zovA:
3.5
3lw5A-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_B_C2FB300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)
5zov -
(-)
5 / 12 PHE A 147
ILE A 353
LEU A 344
GLY A 394
GLN A 427
None
1.45A 4djfB-5zovA:
undetectable
4djfB-5zovA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)
5zov -
(-)
4 / 8 GLY A 356
ILE A 358
ILE A 280
THR A  88
None
ASC  A 501 ( 4.9A)
None
None
0.48A 4em2A-5zovA:
undetectable
4em2A-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)
5zov -
(-)
4 / 4 TYR A  87
THR A 285
VAL A  55
ILE A 280
ASC  A 501 (-4.0A)
None
None
None
1.08A 4jx1F-5zovA:
undetectable
4jx1F-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)
5zov -
(-)
4 / 8 GLU A 391
GLN A 337
VAL A 239
THR A 236
None
0.88A 4lnwA-5zovA:
undetectable
4lnwA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)
5zov -
(-)
4 / 6 GLU A 391
GLN A 337
VAL A 239
THR A 236
None
0.98A 4lnxA-5zovA:
undetectable
4lnxA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 4qvmV-5zovA:
undetectable
4qvmb-5zovA:
undetectable
4qvmV-5zovA:
undetectable
4qvmb-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 4qvmH-5zovA:
undetectable
4qvmN-5zovA:
undetectable
4qvmH-5zovA:
undetectable
4qvmN-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 12 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 4qvnV-5zovA:
undetectable
4qvnb-5zovA:
undetectable
4qvnV-5zovA:
undetectable
4qvnb-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 12 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 4qvnH-5zovA:
undetectable
4qvnN-5zovA:
undetectable
4qvnH-5zovA:
undetectable
4qvnN-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 4qvpV-5zovA:
undetectable
4qvpb-5zovA:
undetectable
4qvpV-5zovA:
undetectable
4qvpb-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.24A 4qvpH-5zovA:
undetectable
4qvpN-5zovA:
undetectable
4qvpH-5zovA:
undetectable
4qvpN-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 4qvqV-5zovA:
undetectable
4qvqb-5zovA:
undetectable
4qvqV-5zovA:
undetectable
4qvqb-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 4qvqH-5zovA:
undetectable
4qvqN-5zovA:
undetectable
4qvqH-5zovA:
undetectable
4qvqN-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 4qw0V-5zovA:
undetectable
4qw0b-5zovA:
undetectable
4qw0V-5zovA:
undetectable
4qw0b-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 4qw0H-5zovA:
undetectable
4qw0N-5zovA:
undetectable
4qw0H-5zovA:
undetectable
4qw0N-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 4qw3V-5zovA:
undetectable
4qw3b-5zovA:
undetectable
4qw3V-5zovA:
undetectable
4qw3b-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 4qw3H-5zovA:
undetectable
4qw3N-5zovA:
undetectable
4qw3H-5zovA:
undetectable
4qw3N-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_A_ASCA501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)
5zov -
(-)
10 / 11 TYR A  87
HIS A 135
ILE A 136
GLN A 139
HIS A 194
GLN A 195
ASP A 314
ALA A 316
PHE A 362
MET A 415
ASC  A 501 (-4.0A)
ASC  A 501 (-4.0A)
None
ASC  A 501 (-3.1A)
ASC  A 501 (-4.0A)
ASC  A 501 (-4.2A)
ASC  A 501 (-2.7A)
ASC  A 501 (-3.6A)
ASC  A 501 (-3.8A)
ASC  A 501 ( 4.6A)
0.32A 4rp8A-5zovA:
44.5
4rp8A-5zovA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)
5zov -
(-)
9 / 12 HIS A 135
ILE A 136
GLN A 139
HIS A 194
GLN A 195
ALA A 316
ILE A 358
PHE A 362
MET A 415
ASC  A 501 (-4.0A)
None
ASC  A 501 (-3.1A)
ASC  A 501 (-4.0A)
ASC  A 501 (-4.2A)
ASC  A 501 (-3.6A)
ASC  A 501 ( 4.9A)
ASC  A 501 (-3.8A)
ASC  A 501 ( 4.6A)
0.35A 4rp8C-5zovA:
44.7
4rp8C-5zovA:
62.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RP9_A_ASCA501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)
5zov -
(-)
11 / 12 TYR A  87
HIS A 135
ILE A 136
GLN A 139
GLN A 195
ASP A 314
CYH A 315
ALA A 316
ILE A 358
PHE A 362
MET A 415
ASC  A 501 (-4.0A)
ASC  A 501 (-4.0A)
None
ASC  A 501 (-3.1A)
ASC  A 501 (-4.2A)
ASC  A 501 (-2.7A)
ASC  A 501 ( 4.3A)
ASC  A 501 (-3.6A)
ASC  A 501 ( 4.9A)
ASC  A 501 (-3.8A)
ASC  A 501 ( 4.6A)
0.35A 4rp9A-5zovA:
40.9
4rp9A-5zovA:
62.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 5cz7H-5zovA:
undetectable
5cz7N-5zovA:
undetectable
5cz7H-5zovA:
undetectable
5cz7N-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 5d0xV-5zovA:
undetectable
5d0xb-5zovA:
undetectable
5d0xV-5zovA:
undetectable
5d0xb-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 5d0xH-5zovA:
undetectable
5d0xN-5zovA:
undetectable
5d0xH-5zovA:
undetectable
5d0xN-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
5zov -
(-)
4 / 5 PHE A 385
LEU A 343
GLY A 342
ILE A 335
None
0.91A 5ik1A-5zovA:
undetectable
5ik1A-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 12 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 5l5zV-5zovA:
undetectable
5l5zb-5zovA:
undetectable
5l5zV-5zovA:
undetectable
5l5zb-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 12 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 5l5zH-5zovA:
undetectable
5l5zN-5zovA:
undetectable
5l5zH-5zovA:
undetectable
5l5zN-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 5l66V-5zovA:
undetectable
5l66b-5zovA:
undetectable
5l66V-5zovA:
undetectable
5l66b-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
5zov -
(-)
5 / 11 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 5l66H-5zovA:
undetectable
5l66N-5zovA:
undetectable
5l66H-5zovA:
undetectable
5l66N-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)
5zov -
(-)
5 / 12 THR A 408
THR A 407
GLY A 411
ALA A  92
THR A  88
None
1.25A 5lf3b-5zovA:
undetectable
5lf3b-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)
5zov -
(-)
4 / 4 LEU A 442
MET A 447
ILE A 425
LEU A 168
None
1.39A 5nfpA-5zovA:
undetectable
5nfpA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)
5zov -
(-)
5 / 8 ILE A  84
VAL A 398
THR A  96
ALA A  92
THR A  93
None
1.32A 5og9A-5zovA:
2.5
5og9A-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)
5zov -
(-)
4 / 7 HIS A 194
GLN A 196
MET A 413
MET A 131
ASC  A 501 (-4.0A)
None
None
None
1.47A 5u6mA-5zovA:
undetectable
5u6mA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_B_SALB503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)
5zov -
(-)
4 / 7 HIS A 194
GLN A 196
MET A 413
MET A 131
ASC  A 501 (-4.0A)
None
None
None
1.39A 5u6mB-5zovA:
undetectable
5u6mB-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)
5zov -
(-)
4 / 8 HIS A 194
GLN A 196
MET A 413
MET A 131
ASC  A 501 (-4.0A)
None
None
None
1.42A 5u6nA-5zovA:
undetectable
5u6nA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)
5zov -
(-)
4 / 8 THR A  45
GLY A  44
LEU A 294
ALA A 297
None
0.74A 5vw5A-5zovA:
undetectable
5vw5A-5zovA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZOV_A_ASCA501_0
(PTS
ASCORBATE-SPECIFIC
SUBUNIT IIBC)
5zov -
(-)
10 / 10 TYR A  87
HIS A 135
ILE A 136
GLN A 139
HIS A 194
GLN A 195
ARG A 288
ASP A 314
ALA A 316
ILE A 358
ASC  A 501 (-4.0A)
ASC  A 501 (-4.0A)
None
ASC  A 501 (-3.1A)
ASC  A 501 (-4.0A)
ASC  A 501 (-4.2A)
ASC  A 501 (-3.0A)
ASC  A 501 (-2.7A)
ASC  A 501 (-3.6A)
ASC  A 501 ( 4.9A)
0.01A 5zovA-5zovA:
74.7
5zovA-5zovA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZOV_B_ASCB501_0
(PTS
ASCORBATE-SPECIFIC
SUBUNIT IIBC)
5zov -
(-)
12 / 12 PRO A  86
TYR A  87
HIS A 135
ILE A 136
GLN A 139
HIS A 194
GLN A 195
ARG A 288
ASP A 314
ALA A 316
ILE A 358
MET A 415
None
ASC  A 501 (-4.0A)
ASC  A 501 (-4.0A)
None
ASC  A 501 (-3.1A)
ASC  A 501 (-4.0A)
ASC  A 501 (-4.2A)
ASC  A 501 (-3.0A)
ASC  A 501 (-2.7A)
ASC  A 501 (-3.6A)
ASC  A 501 ( 4.9A)
ASC  A 501 ( 4.6A)
0.33A 5zovB-5zovA:
69.7
5zovB-5zovA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)
5zov -
(-)
5 / 9 ILE A 399
ALA A  82
GLY A  81
LEU A 352
GLY A 356
None
1.03A 6nm4B-5zovA:
undetectable
6nm4B-5zovA:
undetectable