SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zq6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 5 HIS A 463
GLU A 419
ALA A 530
SER A 457
 None
 1.14A 1errA-5zq6A:
undetectable
1errB-5zq6A:
undetectable		 1errA-5zq6A:
undetectable
1errB-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_A_SAMA417_0
(L-LYSINE
2,3-AMINOMUTASE)		 5zq6 SIDE
(Legionella
pneumophila) 		5 / 11 HIS A 403
THR A 282
ARG A 281
HIS A 274
VAL A 331
 ADP  A1101 (-4.0A)
None
None
ADP  A1101 (-4.5A)
None
 1.42A 2a5hA-5zq6A:
undetectable		 2a5hA-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_B_SAMB417_0
(L-LYSINE
2,3-AMINOMUTASE)		 5zq6 SIDE
(Legionella
pneumophila) 		5 / 12 HIS A 403
THR A 282
ARG A 281
HIS A 274
VAL A 331
 ADP  A1101 (-4.0A)
None
None
ADP  A1101 (-4.5A)
None
 1.43A 2a5hB-5zq6A:
undetectable		 2a5hB-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_C_SAMC417_0
(L-LYSINE
2,3-AMINOMUTASE)		 5zq6 SIDE
(Legionella
pneumophila) 		5 / 12 HIS A 403
THR A 282
ARG A 281
HIS A 274
VAL A 331
 ADP  A1101 (-4.0A)
None
None
ADP  A1101 (-4.5A)
None
 1.42A 2a5hC-5zq6A:
undetectable		 2a5hC-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A5H_D_SAMD417_0
(L-LYSINE
2,3-AMINOMUTASE)		 5zq6 SIDE
(Legionella
pneumophila) 		5 / 12 HIS A 403
THR A 282
ARG A 281
HIS A 274
VAL A 331
 ADP  A1101 (-4.0A)
None
None
ADP  A1101 (-4.5A)
None
 1.42A 2a5hD-5zq6A:
undetectable		 2a5hD-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 6 HIS A 886
ASN A 771
THR A 225
PRO A 224
 None
 1.47A 2ez7A-5zq6A:
undetectable		 2ez7A-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 5 ASP A 352
LEU A 355
LYS A 356
ARG A 351
 None
 1.26A 2gj5A-5zq6A:
undetectable		 2gj5A-5zq6A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 5 GLN A 272
THR A 282
HIS A 403
LEU A 407
 None
None
ADP  A1101 (-4.0A)
ADP  A1101 (-4.8A)
 1.23A 2zj0A-5zq6A:
undetectable		 2zj0A-5zq6A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 5 GLN A 272
THR A 282
HIS A 403
LEU A 407
 None
None
ADP  A1101 (-4.0A)
ADP  A1101 (-4.8A)
 1.31A 3ce6A-5zq6A:
undetectable		 3ce6A-5zq6A:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 5 GLN A 272
THR A 282
HIS A 403
LEU A 407
 None
None
ADP  A1101 (-4.0A)
ADP  A1101 (-4.8A)
 1.30A 3ce6C-5zq6A:
undetectable		 3ce6C-5zq6A:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 4 PRO A 756
LEU A 759
ILE A 835
ARG A 761
 None
 1.35A 3w1wA-5zq6A:
undetectable		 3w1wA-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 7 PRO A1056
ILE A1055
GLY A1027
VAL A1024
 None
 0.95A 4a3uB-5zq6A:
undetectable		 4a3uB-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 7 GLN A 575
THR A 576
THR A 440
THR A 794
 None
 1.07A 4mbsA-5zq6A:
2.6		 4mbsA-5zq6A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 7 ILE A 610
PHE A 634
LEU A 738
THR A 668
 None
 1.03A 4mmcA-5zq6A:
undetectable		 4mmcA-5zq6A:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDC_A_ASDA404_1
(3-KETOSTEROID
9ALPHA-HYDROXYLASE
OXYGENASE)		 5zq6 SIDE
(Legionella
pneumophila) 		5 / 12 VAL A 399
HIS A 278
GLN A 327
LEU A 569
ALA A 286
 None
 1.40A 4qdcA-5zq6A:
undetectable		 4qdcA-5zq6A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 7 SER A 815
PHE A 827
GLU A 855
GLU A 857
 None
 0.63A 4xzkA-5zq6A:
9.8		 4xzkA-5zq6A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 5zq6 SIDE
(Legionella
pneumophila) 		3 / 3 THR A 818
SER A 817
TYR A 858
 None
 0.86A 5jsdA-5zq6A:
undetectable		 5jsdA-5zq6A:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 5zq6 SIDE
(Legionella
pneumophila) 		3 / 3 THR A 818
SER A 817
TYR A 858
 None
 0.87A 5jsdB-5zq6A:
undetectable		 5jsdB-5zq6A:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 5zq6 SIDE
(Legionella
pneumophila) 		3 / 3 THR A 818
SER A 817
TYR A 858
 None
 0.87A 5jsdC-5zq6A:
undetectable		 5jsdC-5zq6A:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 5zq6 SIDE
(Legionella
pneumophila) 		3 / 3 THR A 818
SER A 817
TYR A 858
 None
 0.86A 5jseA-5zq6A:
undetectable		 5jseA-5zq6A:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 5zq6 SIDE
(Legionella
pneumophila) 		3 / 3 THR A 818
SER A 817
TYR A 858
 None
 0.86A 5jseB-5zq6A:
undetectable		 5jseB-5zq6A:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 5zq6 SIDE
(Legionella
pneumophila) 		3 / 3 THR A 818
SER A 817
TYR A 858
 None
 0.87A 5jseC-5zq6A:
undetectable		 5jseC-5zq6A:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5zq6 SIDE
(Legionella
pneumophila) 		5 / 12 LEU A 569
GLU A 559
ASP A 406
GLY A 275
HIS A 278
 None
 1.29A 5utuH-5zq6A:
2.5		 5utuH-5zq6A:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 5 TYR A 713
MET A 739
THR A 740
LEU A 742
 None
 1.42A 5x19J-5zq6A:
1.4		 5x19J-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 6 LEU A 925
LYS A1022
GLU A1026
LEU A1030
 None
 0.86A 5xooA-5zq6A:
undetectable		 5xooA-5zq6A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5zq6 SIDE
(Legionella
pneumophila) 		3 / 3 SER A 854
HIS A 850
TYR A 858
 None
 1.05A 5y2tA-5zq6A:
undetectable		 5y2tA-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5zq6 SIDE
(Legionella
pneumophila) 		5 / 12 ASP A 642
LEU A 911
PRO A 741
GLY A 647
LEU A 650
 None
 1.17A 6b0lB-5zq6A:
undetectable		 6b0lB-5zq6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 5zq6 SIDE
(Legionella
pneumophila) 		3 / 3 ARG A 594
ARG A 593
ASP A 642
 None
 0.97A 6d8pA-5zq6A:
undetectable		 6d8pA-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 6 PHE A 444
LEU A 566
LEU A 569
HIS A 573
 None
 0.61A 6e43A-5zq6A:
2.2		 6e43A-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 6 PHE A 444
LEU A 566
LEU A 569
HIS A 573
 None
 0.61A 6e43B-5zq6A:
undetectable		 6e43B-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 6 PHE A 444
LEU A 566
LEU A 569
HIS A 573
 None
 0.64A 6e43C-5zq6A:
2.6		 6e43C-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5zq6 SIDE
(Legionella
pneumophila) 		4 / 6 PHE A 444
LEU A 566
LEU A 569
HIS A 573
 None
 0.59A 6e43D-5zq6A:
undetectable		 6e43D-5zq6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 5zq6 SIDE
(Legionella
pneumophila) 		3 / 3 HIS A 403
HIS A 274
HIS A 278
 ADP  A1101 (-4.0A)
ADP  A1101 (-4.5A)
None
 0.75A 6giqa-5zq6A:
undetectable		 6giqa-5zq6A:
undetectable