SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		3 / 3 LEU A 365
SER A 355
ASN A 359
 None
 0.83A 1bx4A-5zqjA:
undetectable		 1bx4A-5zqjA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 8 SER A  29
VAL A  72
ASN A 103
ASP A 127
 GOL  A 601 ( 4.7A)
None
None
GOL  A 601 (-3.4A)
 1.22A 1hwiB-5zqjA:
undetectable		 1hwiB-5zqjA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 7 VAL A  72
SER A  89
ASN A 103
ASP A 127
 None
None
None
GOL  A 601 (-3.4A)
 1.22A 1hwiC-5zqjA:
undetectable		 1hwiC-5zqjA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 7 VAL A  72
SER A  89
ASN A 103
ASP A 127
 None
None
None
GOL  A 601 (-3.4A)
 1.22A 1hwiD-5zqjA:
undetectable		 1hwiD-5zqjA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 8 SER A  29
VAL A  72
ASN A 103
ASP A 127
 GOL  A 601 ( 4.7A)
None
None
GOL  A 601 (-3.4A)
 1.23A 1hwkA-5zqjA:
undetectable		 1hwkA-5zqjA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		5 / 8 SER A  29
VAL A  72
SER A  89
ASN A 103
ASP A 127
 GOL  A 601 ( 4.7A)
None
None
None
GOL  A 601 (-3.4A)
 1.23A 1hwkC-5zqjA:
undetectable		 1hwkC-5zqjA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		5 / 8 SER A  29
VAL A  72
SER A  89
ASN A 103
ASP A 127
 GOL  A 601 ( 4.7A)
None
None
None
GOL  A 601 (-3.4A)
 1.23A 1hwkD-5zqjA:
undetectable		 1hwkD-5zqjA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		3 / 3 TRP A  48
ARG A  49
PHE A 323
 None
 1.29A 1zeaH-5zqjA:
undetectable
1zeaL-5zqjA:
undetectable		 1zeaH-5zqjA:
undetectable
1zeaL-5zqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 8 ASP A 477
SER A 475
TYR A 460
TYR A 527
 None
 1.34A 2bteA-5zqjA:
undetectable		 2bteA-5zqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 8 ASP A 477
SER A 475
TYR A 460
TYR A 527
 None
 1.33A 2bteD-5zqjA:
undetectable		 2bteD-5zqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 8 ASP A 477
SER A 475
TYR A 460
TYR A 527
 None
 1.28A 2v0gA-5zqjA:
undetectable		 2v0gA-5zqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		3 / 3 SER A 494
THR A 505
PHE A 379
 None
 0.72A 2x91A-5zqjA:
undetectable		 2x91A-5zqjA:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZS9_A_PAUA603_0
(PANTOTHENATE KINASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 6 VAL A   7
ASP A  44
TYR A 260
ASN A   5
 None
 1.25A 2zs9A-5zqjA:
undetectable		 2zs9A-5zqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 8 GLU A 288
TYR A 530
ARG A 267
PHE A 387
 None
 1.07A 3mjrD-5zqjA:
undetectable		 3mjrD-5zqjA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 8 ARG A 207
HIS A 210
GLY A 502
ASN A 413
 None
 0.93A 3v3nB-5zqjA:
undetectable		 3v3nB-5zqjA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 8 ARG A 207
HIS A 210
GLY A 502
ASN A 413
 None
 0.93A 3v3nC-5zqjA:
undetectable		 3v3nC-5zqjA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		5 / 12 ALA A 406
PHE A 398
ILE A 452
VAL A 459
ILE A 456
 None
 1.06A 4aztA-5zqjA:
undetectable		 4aztA-5zqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_C_ACTC506_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 5 ARG A 280
ILE A 276
HIS A 270
GLY A 281
 None
None
None
GOL  A 603 (-3.5A)
 1.40A 4e7cC-5zqjA:
undetectable		 4e7cC-5zqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 8 ARG A  53
GLY A 506
THR A 505
ARG A 383
 None
 0.91A 4k87A-5zqjA:
undetectable		 4k87A-5zqjA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 5 ILE A 232
ARG A 216
ASP A 298
VAL A 304
 None
 1.24A 4nkxC-5zqjA:
undetectable		 4nkxC-5zqjA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		5 / 12 VAL A 140
ILE A  87
SER A  78
TRP A  85
VAL A 164
 None
 1.47A 4rujA-5zqjA:
undetectable		 4rujA-5zqjA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 7 TRP A 115
ILE A  39
HIS A 132
LEU A 130
 None
 1.19A 4xo7B-5zqjA:
undetectable		 4xo7B-5zqjA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 6 SER A  29
ARG A 207
GLY A 205
GLU A 209
 GOL  A 601 ( 4.7A)
None
None
None
 0.95A 5cdqA-5zqjA:
undetectable
5cdqC-5zqjA:
undetectable
5cdqD-5zqjA:
undetectable		 5cdqA-5zqjA:
9.26
5cdqC-5zqjA:
9.26
5cdqD-5zqjA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		5 / 9 LEU A 190
HIS A 189
VAL A 140
LEU A 159
ARG A 173
 None
 1.49A 5o96E-5zqjA:
undetectable
5o96F-5zqjA:
undetectable		 5o96E-5zqjA:
undetectable
5o96F-5zqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		4 / 6 SER A  59
GLU A 114
ASP A 109
ASP A 117
 None
 1.21A 5zw4A-5zqjA:
undetectable		 5zw4A-5zqjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		5 / 9 TYR A  24
ASP A  44
ALA A 262
ILE A 291
SER A  42
 None
 1.31A 6awoA-5zqjA:
undetectable		 6awoA-5zqjA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5zqj BETA-XYLOSIDASE
(Bacillus
pumilus) 		5 / 9 TYR A  24
ASP A  44
ALA A 262
ILE A 291
SER A  42
 None
 1.31A 6awqA-5zqjA:
undetectable		 6awqA-5zqjA:
10.06