SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zrt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J7K_A_ACTA701_0 (HOLLIDAY JUNCTION DNA HELICASE RUVB)	5zrt	- (-)	4 / 4	GLY A 59 LEU A 54 GLY A 57 ARG A 58	None	1.08A	1j7kA-5zrtA: undetectable	1j7kA-5zrtA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP2_A_PNNA5001_0 (TRANSCRIPTIONAL REGULATOR TCAR)	5zrt	- (-)	4 / 8	ASN A 74 GLN A 44 SER A 40 ASN A 35	None	1.07A	3kp2A-5zrtA: undetectable 3kp2B-5zrtA: undetectable	3kp2A-5zrtA: undetectable 3kp2B-5zrtA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4GRQ_C_AVLC203_1 (MACROPHAGE MIGRATION INHIBITORY FACTOR)	5zrt	- (-)	4 / 7	PHE A 110 GLN A 111 TYR A 28 PHE A 25	None	1.17A	4grqA-5zrtA: undetectable 4grqC-5zrtA: undetectable	4grqA-5zrtA: undetectable 4grqC-5zrtA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IM2_A_BEZA401_0 (TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL)	5zrt	- (-)	5 / 12	PHE A 110 VAL A 98 TRP A 27 LEU A 18 PHE A 25	None	1.23A	5im2A-5zrtA: undetectable	5im2A-5zrtA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1J7K_A_ACTA701_0","HOLLIDAY JUNCTION DNA HELICASE RUVB","5zrt","-","-",4,"GLY A  59;LEU A  54;GLY A  57;ARG A  58","None","1.08A","1j7kA-5zrtA:undetectable","1j7kA-5zrtA:undetectable"],["3KP2_A_PNNA5001_0","TRANSCRIPTIONAL REGULATOR TCAR","5zrt","-","-",4,"ASN A  74;GLN A  44;SER A  40;ASN A  35","None","1.07A","3kp2A-5zrtA:undetectable;3kp2B-5zrtA:undetectable","3kp2A-5zrtA:undetectable;3kp2B-5zrtA:undetectable"],["4GRQ_C_AVLC203_1","MACROPHAGE MIGRATION INHIBITORY FACTOR;MACROPHAGE MIGRATION INHIBITORY FACTOR","5zrt","-","-",4,"PHE A 110;GLN A 111;TYR A  28;PHE A  25","None","1.17A","4grqA-5zrtA:undetectable;4grqC-5zrtA:undetectable","4grqA-5zrtA:undetectable;4grqC-5zrtA:undetectable"],["5IM2_A_BEZA401_0","TWIN-ARGININE TRANSLOCATION PATHWAY SIGNAL","5zrt","-","-",5,"PHE A 110;VAL A  98;TRP A  27;LEU A  18;PHE A  25","None","1.23A","5im2A-5zrtA:undetectable","5im2A-5zrtA:undetectable"]]