SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ztp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		5 / 8 CYH A  38
ASP A  40
HIS A  90
CYH A  93
GLY A  94
 SO4  A 201 (-1.3A)
SO4  A 201 (-3.5A)
SO4  A 201 (-3.0A)
SO4  A 201 (-1.2A)
SO4  A 201 (-3.7A)
 0.46A 1ekjA-5ztpA:
13.9
1ekjB-5ztpA:
13.9		 1ekjA-5ztpA:
undetectable
1ekjB-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		5 / 8 CYH A  38
ASP A  40
HIS A  90
CYH A  93
GLY A  94
 SO4  A 201 (-1.3A)
SO4  A 201 (-3.5A)
SO4  A 201 (-3.0A)
SO4  A 201 (-1.2A)
SO4  A 201 (-3.7A)
 0.99A 1ekjA-5ztpA:
13.9
1ekjB-5ztpA:
13.9		 1ekjA-5ztpA:
undetectable
1ekjB-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		5 / 8 CYH A  93
HIS A  90
CYH A  38
GLY A  64
GLY A  63
 SO4  A 201 (-1.2A)
SO4  A 201 (-3.0A)
SO4  A 201 (-1.3A)
None
SO4  A 201 ( 4.1A)
 1.24A 1ekjA-5ztpA:
13.9
1ekjB-5ztpA:
13.9		 1ekjA-5ztpA:
undetectable
1ekjB-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		5 / 8 CYH A  38
ASP A  40
HIS A  90
CYH A  93
GLY A  94
 SO4  A 201 (-1.3A)
SO4  A 201 (-3.5A)
SO4  A 201 (-3.0A)
SO4  A 201 (-1.2A)
SO4  A 201 (-3.7A)
 0.46A 1ekjA-5ztpA:
13.9
1ekjB-5ztpA:
13.9		 1ekjA-5ztpA:
undetectable
1ekjB-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		4 / 8 CYH A  93
HIS A  90
CYH A  38
GLY A  64
 SO4  A 201 (-1.2A)
SO4  A 201 (-3.0A)
SO4  A 201 (-1.3A)
None
 0.99A 1ekjA-5ztpA:
13.9
1ekjB-5ztpA:
13.9		 1ekjA-5ztpA:
undetectable
1ekjB-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		4 / 7 ASP A  40
HIS A  90
GLY A  63
GLY A  64
 SO4  A 201 (-3.5A)
SO4  A 201 (-3.0A)
SO4  A 201 ( 4.1A)
None
 0.97A 1ekjE-5ztpA:
13.7
1ekjF-5ztpA:
13.8		 1ekjE-5ztpA:
undetectable
1ekjF-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		4 / 7 CYH A  38
ASP A  40
HIS A  90
GLY A  94
 SO4  A 201 (-1.3A)
SO4  A 201 (-3.5A)
SO4  A 201 (-3.0A)
SO4  A 201 (-3.7A)
 0.46A 1ekjE-5ztpA:
13.7
1ekjF-5ztpA:
13.8		 1ekjE-5ztpA:
undetectable
1ekjF-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		4 / 7 CYH A  38
ASP A  40
HIS A  90
GLY A  94
 SO4  A 201 (-1.3A)
SO4  A 201 (-3.5A)
SO4  A 201 (-3.0A)
SO4  A 201 (-3.7A)
 0.99A 1ekjE-5ztpA:
13.7
1ekjF-5ztpA:
13.8		 1ekjE-5ztpA:
undetectable
1ekjF-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		5 / 8 CYH A  38
ASP A  40
HIS A  90
CYH A  93
GLY A  94
 SO4  A 201 (-1.3A)
SO4  A 201 (-3.5A)
SO4  A 201 (-3.0A)
SO4  A 201 (-1.2A)
SO4  A 201 (-3.7A)
 0.46A 1ekjG-5ztpA:
13.7
1ekjH-5ztpA:
13.8		 1ekjG-5ztpA:
undetectable
1ekjH-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		5 / 8 CYH A  38
ASP A  40
HIS A  90
CYH A  93
GLY A  94
 SO4  A 201 (-1.3A)
SO4  A 201 (-3.5A)
SO4  A 201 (-3.0A)
SO4  A 201 (-1.2A)
SO4  A 201 (-3.7A)
 0.97A 1ekjG-5ztpA:
13.7
1ekjH-5ztpA:
13.8		 1ekjG-5ztpA:
undetectable
1ekjH-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		4 / 6 CYH A  38
ASP A  40
HIS A  90
CYH A  93
 SO4  A 201 (-1.3A)
SO4  A 201 (-3.5A)
SO4  A 201 (-3.0A)
SO4  A 201 (-1.2A)
 0.48A 1ekjG-5ztpA:
13.7
1ekjH-5ztpA:
13.8		 1ekjG-5ztpA:
undetectable
1ekjH-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		5 / 10 CYH A  38
ASP A  40
HIS A  90
CYH A  93
GLY A  94
 SO4  A 201 (-1.3A)
SO4  A 201 (-3.5A)
SO4  A 201 (-3.0A)
SO4  A 201 (-1.2A)
SO4  A 201 (-3.7A)
 0.41A 3ucjA-5ztpA:
13.9		 3ucjA-5ztpA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		5 / 10 CYH A  38
ASP A  40
HIS A  90
CYH A  93
GLY A  94
 SO4  A 201 (-1.3A)
SO4  A 201 (-3.5A)
SO4  A 201 (-3.0A)
SO4  A 201 (-1.2A)
SO4  A 201 (-3.7A)
 0.42A 3ucjB-5ztpA:
14.4		 3ucjB-5ztpA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		4 / 8 ILE A 134
ASP A 131
ARG A 157
THR A  91
 None
 1.06A 5hwaA-5ztpA:
undetectable		 5hwaA-5ztpA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5ztp CARBONIC ANHYDRASE
(Glaciozyma
antarctica) 		4 / 8 GLN A  77
THR A 151
VAL A 152
GLU A  84
 None
 1.12A 6fbvC-5ztpA:
undetectable		 6fbvC-5ztpA:
undetectable