SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zu6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_B_CAMB502_0
(CYTOCHROME P450-CAM)		 5zu6 CBM32 DOMAIN
(Vibrio) 		4 / 5 PHE A 108
VAL A  80
VAL A 138
ASP A  60
 None
 1.47A 1dz6B-5zu6A:
undetectable		 1dz6B-5zu6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 5zu6 CBM32 DOMAIN
(Vibrio) 		3 / 4 VAL A 132
TRP A 129
TRP A  40
 None
 0.94A 1gmkA-5zu6A:
undetectable
1gmkB-5zu6A:
undetectable		 1gmkA-5zu6A:
undetectable
1gmkB-5zu6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5zu6 CBM32 DOMAIN
(Vibrio) 		3 / 3 GLU A  47
ASN A 130
TRP A  40
 None
 1.08A 1r15C-5zu6A:
undetectable		 1r15C-5zu6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5zu6 CBM32 DOMAIN
(Vibrio) 		3 / 3 GLU A  47
ASN A 130
TRP A  40
 None
 1.06A 1r15D-5zu6A:
undetectable		 1r15D-5zu6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5zu6 CBM32 DOMAIN
(Vibrio) 		3 / 3 GLU A  47
ASN A 130
TRP A  40
 None
 1.10A 1r15E-5zu6A:
undetectable		 1r15E-5zu6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 5zu6 CBM32 DOMAIN
(Vibrio) 		3 / 3 GLU A  47
ASN A 130
TRP A  40
 None
 1.12A 1r15F-5zu6A:
undetectable		 1r15F-5zu6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 5zu6 CBM32 DOMAIN
(Vibrio) 		3 / 3 ASP A  77
PHE A 106
ASN A 130
 None
 0.85A 1sg9B-5zu6A:
undetectable		 1sg9B-5zu6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 5zu6 CBM32 DOMAIN
(Vibrio) 		4 / 7 ASP A  35
THR A 133
ILE A 101
ASN A  70
 None
 1.19A 2jc9A-5zu6A:
undetectable		 2jc9A-5zu6A:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 5zu6 CBM32 DOMAIN
(Vibrio) 		4 / 8 HIS A  23
GLY A  27
ASN A  26
ARG A  30
 None
 1.41A 3ccfA-5zu6A:
undetectable		 3ccfA-5zu6A:
undetectable