SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5zxd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5zxd -
(-) 		5 / 9 LEU A 228
VAL A  37
GLY A  35
LEU A  26
TYR A 230
 None
 1.31A 1lwfA-5zxdA:
undetectable		 1lwfA-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 VAL A 513
VAL A 364
PHE A 343
GLU A 515
 None
ATP  A 602 ( 4.6A)
None
None
 1.26A 1zzrA-5zxdA:
undetectable
1zzrB-5zxdA:
undetectable		 1zzrA-5zxdA:
undetectable
1zzrB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.25A 1zzrA-5zxdA:
undetectable
1zzrB-5zxdA:
undetectable		 1zzrA-5zxdA:
undetectable
1zzrB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 VAL A 513
VAL A 364
PHE A 343
GLU A 515
 None
ATP  A 602 ( 4.6A)
None
None
 1.26A 1zzuA-5zxdA:
undetectable
1zzuB-5zxdA:
1.9		 1zzuA-5zxdA:
undetectable
1zzuB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.26A 1zzuA-5zxdA:
0.1
1zzuB-5zxdA:
1.9		 1zzuA-5zxdA:
undetectable
1zzuB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5zxd -
(-) 		3 / 3 ASP A 215
ASP A 209
ASN A 194
 None
 0.77A 2bm9D-5zxdA:
undetectable		 2bm9D-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 5zxd -
(-) 		5 / 12 GLU A 539
TRP A 191
LEU A 168
GLY A 198
VAL A 216
 None
 1.23A 2kceA-5zxdA:
undetectable		 2kceA-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5zxd -
(-) 		4 / 5 LEU A 137
GLN A  69
THR A  76
LEU A 184
 None
 1.19A 3ce6D-5zxdA:
undetectable		 3ce6D-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 VAL A 513
VAL A 364
PHE A 343
GLU A 515
 None
ATP  A 602 ( 4.6A)
None
None
 1.23A 3dqrA-5zxdA:
undetectable
3dqrB-5zxdA:
undetectable		 3dqrA-5zxdA:
undetectable
3dqrB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.22A 3dqrA-5zxdA:
undetectable
3dqrB-5zxdA:
undetectable		 3dqrA-5zxdA:
undetectable
3dqrB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.25A 3jx2A-5zxdA:
undetectable
3jx2B-5zxdA:
undetectable		 3jx2A-5zxdA:
undetectable
3jx2B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 VAL A 513
VAL A 364
PHE A 343
GLU A 515
 None
ATP  A 602 ( 4.6A)
None
None
 1.26A 3jx3A-5zxdA:
0.1
3jx3B-5zxdA:
undetectable		 3jx3A-5zxdA:
undetectable
3jx3B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.25A 3jx3A-5zxdA:
0.1
3jx3B-5zxdA:
undetectable		 3jx3A-5zxdA:
undetectable
3jx3B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.22A 3jx4A-5zxdA:
undetectable
3jx4B-5zxdA:
undetectable		 3jx4A-5zxdA:
undetectable
3jx4B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.24A 3jx5A-5zxdA:
undetectable
3jx5B-5zxdA:
undetectable		 3jx5A-5zxdA:
undetectable
3jx5B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.25A 3jx6A-5zxdA:
undetectable
3jx6B-5zxdA:
undetectable		 3jx6A-5zxdA:
undetectable
3jx6B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 5zxd -
(-) 		5 / 12 ASP A 209
LEU A 468
SER A 498
ILE A 487
LEU A 483
 None
 1.13A 3ko0G-5zxdA:
undetectable
3ko0H-5zxdA:
undetectable
3ko0I-5zxdA:
undetectable
3ko0J-5zxdA:
undetectable		 3ko0G-5zxdA:
undetectable
3ko0H-5zxdA:
undetectable
3ko0I-5zxdA:
undetectable
3ko0J-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 5zxd -
(-) 		4 / 8 GLY A 448
ILE A 480
PHE A 455
PHE A 431
 None
 0.92A 3ko0K-5zxdA:
undetectable
3ko0S-5zxdA:
undetectable		 3ko0K-5zxdA:
undetectable
3ko0S-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 5zxd -
(-) 		5 / 12 ASP A 209
LEU A 483
LEU A 468
SER A 498
ILE A 487
 None
 1.14A 3ko0M-5zxdA:
undetectable
3ko0N-5zxdA:
undetectable
3ko0O-5zxdA:
undetectable
3ko0P-5zxdA:
undetectable		 3ko0M-5zxdA:
undetectable
3ko0N-5zxdA:
undetectable
3ko0O-5zxdA:
undetectable
3ko0P-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 5zxd -
(-) 		4 / 6 VAL A 513
VAL A 364
PHE A 343
GLU A 515
 None
ATP  A 602 ( 4.6A)
None
None
 1.25A 3n61A-5zxdA:
undetectable
3n61B-5zxdA:
undetectable		 3n61A-5zxdA:
undetectable
3n61B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.25A 3n61A-5zxdA:
undetectable
3n61B-5zxdA:
undetectable		 3n61A-5zxdA:
undetectable
3n61B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.26A 3nljA-5zxdA:
undetectable
3nljB-5zxdA:
undetectable		 3nljA-5zxdA:
undetectable
3nljB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 VAL A 513
VAL A 364
PHE A 343
GLU A 515
 None
ATP  A 602 ( 4.6A)
None
None
 1.26A 3nlpA-5zxdA:
undetectable
3nlpB-5zxdA:
undetectable		 3nlpA-5zxdA:
undetectable
3nlpB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.24A 3nlpA-5zxdA:
undetectable
3nlpB-5zxdA:
undetectable		 3nlpA-5zxdA:
undetectable
3nlpB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.29A 3nlqA-5zxdA:
undetectable
3nlqB-5zxdA:
undetectable		 3nlqA-5zxdA:
undetectable
3nlqB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 VAL A 513
VAL A 364
PHE A 343
GLU A 515
 None
ATP  A 602 ( 4.6A)
None
None
 1.25A 3nlrA-5zxdA:
undetectable
3nlrB-5zxdA:
undetectable		 3nlrA-5zxdA:
undetectable
3nlrB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5zxd -
(-) 		4 / 8 VAL A 497
CYH A 509
VAL A 359
ILE A 356
 None
 1.12A 4aftD-5zxdA:
undetectable
4aftE-5zxdA:
undetectable		 4aftD-5zxdA:
undetectable
4aftE-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 VAL A 513
VAL A 364
PHE A 343
GLU A 515
 None
ATP  A 602 ( 4.6A)
None
None
 1.27A 4cx3A-5zxdA:
undetectable
4cx3B-5zxdA:
undetectable		 4cx3A-5zxdA:
undetectable
4cx3B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.26A 4cx3A-5zxdA:
undetectable
4cx3B-5zxdA:
undetectable		 4cx3A-5zxdA:
undetectable
4cx3B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 VAL A 513
VAL A 364
PHE A 343
GLU A 515
 None
ATP  A 602 ( 4.6A)
None
None
 1.27A 4cx4A-5zxdA:
undetectable
4cx4B-5zxdA:
undetectable		 4cx4A-5zxdA:
undetectable
4cx4B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.24A 4cx4A-5zxdA:
undetectable
4cx4B-5zxdA:
undetectable		 4cx4A-5zxdA:
undetectable
4cx4B-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5zxd -
(-) 		4 / 5 GLY A 447
GLY A 448
ASN A  40
GLU A 401
 None
None
ATP  A 601 (-3.9A)
None
 1.04A 4fglC-5zxdA:
undetectable		 4fglC-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 5zxd -
(-) 		5 / 10 ALA A 400
PHE A 395
GLU A 470
PHE A 455
LEU A 483
 None
None
ATP  A 602 (-4.7A)
None
None
 1.38A 4la0A-5zxdA:
undetectable		 4la0A-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5zxd -
(-) 		5 / 10 LEU A 196
LEU A 203
LEU A 177
THR A 181
LEU A 192
 None
 1.04A 4z91A-5zxdA:
undetectable
4z91B-5zxdA:
undetectable
4z91C-5zxdA:
undetectable
4z91D-5zxdA:
undetectable
4z91E-5zxdA:
undetectable		 4z91A-5zxdA:
undetectable
4z91B-5zxdA:
undetectable
4z91C-5zxdA:
undetectable
4z91D-5zxdA:
undetectable
4z91E-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5zxd -
(-) 		5 / 10 LEU A 203
LEU A 177
THR A 181
LEU A 192
LEU A 196
 None
 1.04A 4z91A-5zxdA:
undetectable
4z91B-5zxdA:
undetectable
4z91C-5zxdA:
undetectable
4z91D-5zxdA:
undetectable
4z91E-5zxdA:
undetectable		 4z91A-5zxdA:
undetectable
4z91B-5zxdA:
undetectable
4z91C-5zxdA:
undetectable
4z91D-5zxdA:
undetectable
4z91E-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5zxd -
(-) 		5 / 10 THR A 181
LEU A 192
LEU A 196
LEU A 203
LEU A 177
 None
 1.02A 4z91A-5zxdA:
undetectable
4z91B-5zxdA:
undetectable
4z91C-5zxdA:
undetectable
4z91D-5zxdA:
undetectable
4z91E-5zxdA:
undetectable		 4z91A-5zxdA:
undetectable
4z91B-5zxdA:
undetectable
4z91C-5zxdA:
undetectable
4z91D-5zxdA:
undetectable
4z91E-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.26A 5addA-5zxdA:
undetectable
5addB-5zxdA:
undetectable		 5addA-5zxdA:
undetectable
5addB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.25A 5adeA-5zxdA:
undetectable
5adeB-5zxdA:
0.1		 5adeA-5zxdA:
undetectable
5adeB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 VAL A 513
VAL A 364
PHE A 343
GLU A 515
 None
ATP  A 602 ( 4.6A)
None
None
 1.26A 5g0pA-5zxdA:
undetectable
5g0pB-5zxdA:
undetectable		 5g0pA-5zxdA:
undetectable
5g0pB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5zxd -
(-) 		4 / 7 PHE A 343
GLU A 515
VAL A 513
VAL A 364
 None
None
None
ATP  A 602 ( 4.6A)
 1.24A 5g0pA-5zxdA:
undetectable
5g0pB-5zxdA:
undetectable		 5g0pA-5zxdA:
undetectable
5g0pB-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 5zxd -
(-) 		5 / 11 TYR A 230
PHE A 238
GLY A 233
ILE A 221
VAL A  37
 None
 1.08A 5hjiA-5zxdA:
undetectable		 5hjiA-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 5zxd -
(-) 		4 / 6 LYS A 258
GLU A 262
ALA A 265
LYS A 264
 None
 1.22A 6an0A-5zxdA:
undetectable		 6an0A-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)		 5zxd -
(-) 		4 / 5 GLU A  75
PRO A 150
THR A 151
GLN A 152
 None
 0.97A 6fgdA-5zxdA:
undetectable		 6fgdA-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 5zxd -
(-) 		3 / 3 ARG A 452
PHE A 431
GLY A 432
 None
 0.74A 6fgdA-5zxdA:
undetectable		 6fgdA-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5zxd -
(-) 		4 / 6 GLY A 429
LEU A 428
PHE A 455
PHE A 316
 None
 0.86A 6h7lA-5zxdA:
undetectable		 6h7lA-5zxdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5zxd -
(-) 		4 / 6 GLY A 429
LEU A 428
PHE A 455
PHE A 316
 None
 0.85A 6h7lB-5zxdA:
undetectable		 6h7lB-5zxdA:
undetectable