SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6a0x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 6a0x ANTIBODY 13D4, FAB
HEAVY CHAIN
(Mus
musculus) 		5 / 12 ASP A  86
PHE A  63
MET A  77
PHE A  69
GLY A  65
 None
 1.22A 2fqyA-6a0xA:
undetectable		 2fqyA-6a0xA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 6a0x ANTIBODY 13D4, FAB
HEAVY CHAIN
(Mus
musculus) 		4 / 5 SER A 112
ALA A 114
PHE A 146
LEU A 170
 None
 0.33A 5mthA-6a0xA:
28.0		 5mthA-6a0xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 6a0x ANTIBODY 13D4, FAB
HEAVY CHAIN
(Mus
musculus) 		4 / 6 ASN A  73
ALA A  24
PRO A  52
TYR A  27
 None
 1.08A 5umd2-6a0xA:
undetectable
5umdF-6a0xA:
undetectable		 5umd2-6a0xA:
22.99
5umdF-6a0xA:
24.42