SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6a0z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 6a0z HEMAGGLUTININ,ENVELO
PE GLYCOPROTEIN
(Human
immunodeficiency
virus
1;
Influenza
A
virus) 		4 / 4 LEU A  70
PRO A  58
ILE A 267
LEU A 112
 None
 1.13A 1ya4B-6a0zA:
undetectable		 1ya4B-6a0zA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 6a0z HEMAGGLUTININ,ENVELO
PE GLYCOPROTEIN
(Human
immunodeficiency
virus
1;
Influenza
A
virus) 		4 / 4 LEU A  70
PRO A  58
ILE A 267
LEU A 112
 None
 1.17A 1ya4C-6a0zA:
undetectable		 1ya4C-6a0zA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6a0z HEMAGGLUTININ,ENVELO
PE GLYCOPROTEIN
(Human
immunodeficiency
virus
1;
Influenza
A
virus) 		5 / 12 ILE A 260
PHE A 118
SER A 265
ILE A  87
ILE A 115
 None
 1.12A 2bl9A-6a0zA:
undetectable		 2bl9A-6a0zA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 6a0z HEMAGGLUTININ,ENVELO
PE GLYCOPROTEIN
(Human
immunodeficiency
virus
1;
Influenza
A
virus) 		4 / 7 TYR A 195
TYR A 161
ALA A 132
ILE A 252
 None
 1.07A 4uymB-6a0zA:
undetectable		 4uymB-6a0zA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 6a0z HEMAGGLUTININ,ENVELO
PE GLYCOPROTEIN
(Human
immunodeficiency
virus
1;
Influenza
A
virus) 		4 / 8 ASN A 244
PHE A 245
SER A 247
TYR A 201
 None
 1.22A 5amiB-6a0zA:
undetectable		 5amiB-6a0zA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 6a0z HEMAGGLUTININ,ENVELO
PE GLYCOPROTEIN
(Human
immunodeficiency
virus
1;
Influenza
A
virus) 		4 / 7 THR A 160
TYR A 161
PRO A 162
THR A 163
 None
 1.32A 5b6iA-6a0zA:
undetectable		 5b6iA-6a0zA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 6a0z HEMAGGLUTININ,ENVELO
PE GLYCOPROTEIN
(Influenza
A
virus;
Human
immunodeficiency
virus
1) 		4 / 6 ASN A 170
THR A 171
ASN A 172
ILE A 121
 None
 1.02A 5uigA-6a0zA:
undetectable		 5uigA-6a0zA:
undetectable