SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6a2f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 6a2f -
(-) 		4 / 7 HIS A  40
GLY A  39
ALA A  37
TYR A  38
 None
None
None
LLP  A  34 ( 4.5A)
 0.91A 1dmaA-6a2fA:
undetectable		 1dmaA-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 6a2f -
(-) 		4 / 6 ASP A  97
LEU A  98
VAL A  99
ILE A 100
 None
 0.85A 1s9qA-6a2fA:
undetectable		 1s9qA-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 6a2f -
(-) 		3 / 3 TRP A 324
ALA A 326
VAL A 330
 None
 0.94A 1w5uA-6a2fA:
undetectable
1w5uB-6a2fA:
undetectable		 1w5uA-6a2fA:
undetectable
1w5uB-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 6a2f -
(-) 		3 / 3 ALA A 326
VAL A 330
TRP A 324
 None
 0.89A 2izqA-6a2fA:
undetectable
2izqB-6a2fA:
undetectable		 2izqA-6a2fA:
undetectable
2izqB-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 6a2f -
(-) 		5 / 12 ALA A 334
GLY A 216
LEU A 230
ASP A 331
LEU A 344
 None
 1.32A 2nv4A-6a2fA:
2.6		 2nv4A-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 6a2f -
(-) 		5 / 12 LEU A 179
LEU A 175
GLN A 173
LEU A 124
ASP A 125
 None
 1.28A 3gwuA-6a2fA:
undetectable		 3gwuA-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3008_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 6a2f -
(-) 		4 / 7 GLU A  66
VAL A  46
VAL A  58
ALA A  64
 None
None
LLP  A  34 ( 4.5A)
None
 1.02A 3kp6B-6a2fA:
undetectable		 3kp6B-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 6a2f -
(-) 		3 / 3 TRP A 324
ALA A 326
VAL A 330
 None
 0.94A 3l8lA-6a2fA:
undetectable
3l8lB-6a2fA:
undetectable		 3l8lA-6a2fA:
undetectable
3l8lB-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 6a2f -
(-) 		3 / 3 TRP A 324
ALA A 326
VAL A 330
 None
 0.98A 3l8lC-6a2fA:
undetectable
3l8lD-6a2fA:
undetectable		 3l8lC-6a2fA:
undetectable
3l8lD-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 6a2f -
(-) 		4 / 7 ALA A 315
PRO A 313
LEU A 243
LEU A 240
 None
 0.84A 4iomA-6a2fA:
2.4		 4iomA-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 6a2f -
(-) 		5 / 11 SER A 194
SER A 217
LEU A 230
ASP A 331
LEU A 340
 LLP  A  34 ( 2.5A)
None
None
None
None
 1.41A 4or0A-6a2fA:
undetectable		 4or0A-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 6a2f -
(-) 		5 / 10 ALA A  64
LEU A  79
LEU A  96
LEU A  90
ALA A  91
 None
LLP  A  34 ( 3.9A)
None
None
None
 1.20A 4zbrA-6a2fA:
undetectable		 4zbrA-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 6a2f -
(-) 		5 / 12 ARG A 293
LEU A 328
LEU A 305
VAL A 307
GLY A 284
 None
 1.37A 5i8fA-6a2fA:
undetectable		 5i8fA-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 6a2f -
(-) 		4 / 4 HIS A  40
VAL A 330
LEU A 345
ALA A 233
 None
 1.16A 6d8pB-6a2fA:
undetectable		 6d8pB-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 6a2f -
(-) 		5 / 10 ILE A 241
VAL A 287
ALA A 294
LEU A 240
LEU A 305
 None
 1.01A 6f6nA-6a2fA:
undetectable
6f6nB-6a2fA:
undetectable		 6f6nA-6a2fA:
undetectable
6f6nB-6a2fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 6a2f -
(-) 		4 / 4 HIS A  40
LEU A  49
TYR A  17
GLY A 211
 None
None
None
LLP  A  34 ( 3.4A)
 1.46A 6n91A-6a2fA:
5.3		 6n91A-6a2fA:
undetectable