SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6a31'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		5 / 12 VAL A  76
LEU A   6
ALA A  89
ILE A 125
ILE A  85
 None
 1.05A 1fk6A-6a31A:
undetectable		 1fk6A-6a31A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		4 / 5 ASP A  95
GLY A 151
PRO A 139
ILE A 136
 None
 1.00A 2aoiA-6a31A:
undetectable		 2aoiA-6a31A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		4 / 8 HIS A  22
GLY A  11
ASN A  23
TYR A  17
 None
 1.27A 3ccfA-6a31A:
undetectable		 3ccfA-6a31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		5 / 10 ILE A   4
ILE A   7
VAL A  29
GLY A  25
VAL A  76
 None
 1.17A 3elzC-6a31A:
undetectable		 3elzC-6a31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		4 / 8 PHE A  79
TYR A  83
LEU A  64
PRO A  65
 None
 1.10A 3jq7B-6a31A:
undetectable		 3jq7B-6a31A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  32
GLY A  25
ALA A  93
LEU A  91
LEU A  64
 None
 0.99A 3p5nA-6a31A:
undetectable		 3p5nA-6a31A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  32
GLY A  25
ALA A  93
LEU A  91
LEU A  64
 None
 0.99A 3p5nB-6a31A:
undetectable		 3p5nB-6a31A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		4 / 5 LEU A 118
ILE A  92
LEU A  91
ARG A 131
 None
 0.78A 4mghA-6a31A:
undetectable		 4mghA-6a31A:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		9 / 9 HIS A  22
LEU A  97
GLY A 114
HIS A 115
ASN A 116
VAL A 145
SER A 146
VAL A 149
LEU A 150
 None
 0.70A 4qd3A-6a31A:
34.1		 4qd3A-6a31A:
31.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB201_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		5 / 8 GLU A  96
HIS A 115
GLY A 113
GLY A 114
HIS A  94
 None
 1.32A 5f8yB-6a31A:
undetectable		 5f8yB-6a31A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		4 / 7 HIS A 115
HIS A 138
ILE A 136
VAL A 149
 None
 1.28A 5kkzM-6a31A:
undetectable
5kkzO-6a31A:
undetectable		 5kkzM-6a31A:
undetectable
5kkzO-6a31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		4 / 5 TYR A  83
ILE A  85
LEU A  40
GLY A  51
 None
None
NA  A 201 (-4.3A)
None
 0.88A 5kmdC-6a31A:
undetectable
5kmdD-6a31A:
undetectable		 5kmdC-6a31A:
14.45
5kmdD-6a31A:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		4 / 6 HIS A  22
ASP A  95
HIS A 115
MET A  69
 None
 1.46A 5m45A-6a31A:
undetectable		 5m45A-6a31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		4 / 6 HIS A  22
ASP A  95
HIS A 115
MET A  69
 None
 1.45A 5m45D-6a31A:
0.0		 5m45D-6a31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		4 / 6 HIS A  22
ASP A  95
HIS A 115
MET A  69
 None
 1.46A 5m45G-6a31A:
0.0		 5m45G-6a31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		4 / 6 HIS A  22
ASP A  95
HIS A 115
MET A  69
 None
 1.45A 5m45J-6a31A:
undetectable		 5m45J-6a31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		5 / 10 ILE A   7
LEU A  32
ILE A 165
ALA A 168
ILE A 187
 None
 0.93A 5mvmD-6a31A:
undetectable
5mvmE-6a31A:
undetectable		 5mvmD-6a31A:
23.40
5mvmE-6a31A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		4 / 8 ASN A  54
ARG A  52
ILE A  38
GLY A  51
 None
 0.96A 5nzxA-6a31A:
3.3		 5nzxA-6a31A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		3 / 3 HIS A  22
ASP A  95
HIS A 115
 None
 0.67A 5oexA-6a31A:
undetectable		 5oexA-6a31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		3 / 3 HIS A  22
ASP A  95
HIS A 115
 None
 0.72A 5oexB-6a31A:
undetectable		 5oexB-6a31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		3 / 3 HIS A  22
ASP A  95
HIS A 115
 None
 0.72A 5oexC-6a31A:
undetectable		 5oexC-6a31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		3 / 3 HIS A  22
ASP A  95
HIS A 115
 None
 0.74A 5oexD-6a31A:
undetectable		 5oexD-6a31A:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y9A_A_AR3A201_1
(PEPTIDYL-TRNA
HYDROLASE)		 6a31 PEPTIDYL-TRNA
HYDROLASE
(Acinetobacter
baumannii) 		6 / 6 ALA A  18
GLN A  19
TRP A  27
LYS A 152
GLN A 158
ASP A 162
 None
 0.58A 5y9aA-6a31A:
38.5		 5y9aA-6a31A:
100.00