SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6a70'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 6a70 -
(-) 		5 / 12 GLY B3300
ALA B3578
SER B3579
TRP B3575
GLY B3303
 None
 1.13A 1nbiC-6a70B:
undetectable		 1nbiC-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 6a70 -
(-) 		5 / 12 GLY B3300
ALA B3578
SER B3579
TRP B3575
GLY B3303
 None
 1.09A 1nbiD-6a70B:
undetectable		 1nbiD-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 6a70 -
(-) 		4 / 6 LEU B3907
PHE B3910
ALA B3911
LEU B3994
 None
 0.99A 1ukbA-6a70B:
undetectable		 1ukbA-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 6a70 -
(-) 		3 / 3 ARG B3970
GLY B3745
PRO B3746
 None
 0.61A 2hreD-6a70B:
undetectable		 2hreD-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 6a70 -
(-) 		4 / 8 ALA B3567
ALA B3571
GLY B3293
CYH B3081
 None
 0.83A 2vh3B-6a70B:
2.1		 2vh3B-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 6a70 -
(-) 		5 / 11 ALA B3889
LEU B3863
PRO B3887
SER B3984
ARG B3952
 None
 1.50A 3bpxA-6a70B:
undetectable
3bpxB-6a70B:
1.5		 3bpxA-6a70B:
undetectable
3bpxB-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC2_1
(CYTOCHROME P450 2D6)		 6a70 -
(-) 		5 / 10 LEU B3674
THR B3087
VAL B3683
PHE B3914
PHE B3910
 None
 1.40A 3tbgC-6a70B:
undetectable		 3tbgC-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 6a70 -
(-) 		5 / 9 THR B3903
LEU B3907
ALA B3687
LEU B3995
THR B3948
 None
 1.15A 4ltwA-6a70B:
undetectable		 4ltwA-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 6a70 -
(-) 		4 / 5 PHE B3977
PHE B3888
LEU B3956
PRO B3900
 None
 1.38A 4o8zA-6a70B:
undetectable		 4o8zA-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 6a70 -
(-) 		5 / 12 PHE B3888
ALA B3866
THR B3964
VAL B3967
LEU B3744
 None
 1.10A 4qynA-6a70B:
undetectable		 4qynA-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 6a70 -
(-) 		4 / 5 ALA B3889
ARG B3952
HIS B3697
ALA B3692
 None
 1.24A 5a06C-6a70B:
undetectable
5a06D-6a70B:
undetectable		 5a06C-6a70B:
undetectable
5a06D-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 6a70 -
(-) 		4 / 6 ALA B3865
THR B3855
VAL B3867
HIS B3864
 None
 0.99A 5ecoA-6a70B:
undetectable		 5ecoA-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 6a70 -
(-) 		4 / 8 GLY B3804
LEU B3802
GLN B3979
ALA B3958
 None
 0.87A 5xu8A-6a70B:
undetectable		 5xu8A-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 6a70 -
(-) 		4 / 6 LEU B3286
LEU B3565
TYR B3334
LEU B3341
 None
 1.06A 6f6sA-6a70B:
undetectable
6f6sB-6a70B:
0.0		 6f6sA-6a70B:
undetectable
6f6sB-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6a70 -
(-) 		4 / 6 TRP B3936
GLY B3926
TRP B3922
ALA B3935
 None
 1.05A 6fosA-6a70B:
4.2		 6fosA-6a70B:
undetectable