SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6a8l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 1c9sJ-6a8lA:
undetectable
1c9sK-6a8lA:
undetectable		 1c9sJ-6a8lA:
undetectable
1c9sK-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_1
(DIHYDROFOLATE
REDUCTASE)		 6a8l -
(-) 		5 / 12 ILE A   8
ILE A 151
LEU A 118
LEU A 114
ILE A   6
 None
 0.95A 1df7A-6a8lA:
undetectable		 1df7A-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 1gtfA-6a8lA:
undetectable
1gtfB-6a8lA:
undetectable		 1gtfA-6a8lA:
undetectable
1gtfB-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 1gtfI-6a8lA:
undetectable
1gtfJ-6a8lA:
undetectable		 1gtfI-6a8lA:
undetectable
1gtfJ-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 6a8l -
(-) 		3 / 3 ARG A  84
THR A  38
VAL A  35
 None
 0.95A 1hxbA-6a8lA:
undetectable		 1hxbA-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 6a8l -
(-) 		5 / 12 GLU A  64
HIS A  62
HIS A  71
ASN A  72
ASP A  53
 ZN  A 200 (-2.4A)
None
ZN  A 200 (-3.4A)
None
ZN  A 200 (-2.7A)
 1.30A 1ituA-6a8lA:
undetectable		 1ituA-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.47A 1utdA-6a8lA:
undetectable
1utdB-6a8lA:
undetectable		 1utdA-6a8lA:
undetectable
1utdB-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.48A 1utdD-6a8lA:
undetectable
1utdE-6a8lA:
undetectable		 1utdD-6a8lA:
undetectable
1utdE-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.48A 1utdG-6a8lA:
undetectable
1utdH-6a8lA:
undetectable		 1utdG-6a8lA:
undetectable
1utdH-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WT9_A_NIOA1216_1
(NICOTINAMIDASE)		 6a8l -
(-) 		5 / 10 ASP A   9
ASP A  53
HIS A  55
TYR A 106
CYH A 136
 None
ZN  A 200 (-2.7A)
ZN  A 200 (-3.2A)
None
None
 1.19A 2wt9A-6a8lA:
22.3		 2wt9A-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WT9_A_NIOA1216_1
(NICOTINAMIDASE)		 6a8l -
(-) 		7 / 10 ASP A   9
PHE A  14
LEU A  21
ASP A  53
HIS A  71
TYR A 106
CYH A 136
 None
None
None
ZN  A 200 (-2.7A)
ZN  A 200 (-3.4A)
None
None
 0.63A 2wt9A-6a8lA:
22.3		 2wt9A-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WT9_B_NIOB1216_1
(NICOTINAMIDASE)		 6a8l -
(-) 		6 / 9 ASP A   9
PHE A  14
LEU A  21
ASP A  53
HIS A  71
CYH A 136
 None
None
None
ZN  A 200 (-2.7A)
ZN  A 200 (-3.4A)
None
 0.65A 2wt9B-6a8lA:
22.1		 2wt9B-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 6a8l -
(-) 		5 / 10 ILE A 151
ILE A 153
SER A 107
LEU A 138
HIS A 172
 None
 1.28A 3o1xA-6a8lA:
undetectable		 3o1xA-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 6a8l -
(-) 		5 / 11 ASP A   9
ASP A  53
GLU A  64
HIS A  55
TYR A 106
 None
ZN  A 200 (-2.7A)
ZN  A 200 (-2.4A)
ZN  A 200 (-3.2A)
None
 1.36A 3o94A-6a8lA:
34.0		 3o94A-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 6a8l -
(-) 		9 / 11 ASP A   9
PHE A  14
LEU A  21
ASP A  53
GLU A  64
PHE A  68
HIS A  71
TYR A 106
ILE A 135
 None
None
None
ZN  A 200 (-2.7A)
ZN  A 200 (-2.4A)
None
ZN  A 200 (-3.4A)
None
None
 0.74A 3o94A-6a8lA:
34.0		 3o94A-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 6a8l -
(-) 		5 / 11 ASP A   9
ASP A  53
GLU A  64
HIS A  55
TYR A 106
 None
ZN  A 200 (-2.7A)
ZN  A 200 (-2.4A)
ZN  A 200 (-3.2A)
None
 1.34A 3o94B-6a8lA:
34.0		 3o94B-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 6a8l -
(-) 		9 / 11 ASP A   9
PHE A  14
LEU A  21
ASP A  53
GLU A  64
PHE A  68
HIS A  71
TYR A 106
ILE A 135
 None
None
None
ZN  A 200 (-2.7A)
ZN  A 200 (-2.4A)
None
ZN  A 200 (-3.4A)
None
None
 0.69A 3o94B-6a8lA:
34.0		 3o94B-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 6a8l -
(-) 		5 / 11 ASP A   9
ASP A  53
GLU A  64
HIS A  55
TYR A 106
 None
ZN  A 200 (-2.7A)
ZN  A 200 (-2.4A)
ZN  A 200 (-3.2A)
None
 1.36A 3o94C-6a8lA:
33.9		 3o94C-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 6a8l -
(-) 		9 / 11 ASP A   9
PHE A  14
LEU A  21
ASP A  53
GLU A  64
PHE A  68
HIS A  71
TYR A 106
ILE A 135
 None
None
None
ZN  A 200 (-2.7A)
ZN  A 200 (-2.4A)
None
ZN  A 200 (-3.4A)
None
None
 0.72A 3o94C-6a8lA:
33.9		 3o94C-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 6a8l -
(-) 		5 / 11 ASP A   9
ASP A  53
GLU A  64
HIS A  55
TYR A 106
 None
ZN  A 200 (-2.7A)
ZN  A 200 (-2.4A)
ZN  A 200 (-3.2A)
None
 1.36A 3o94D-6a8lA:
33.9		 3o94D-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 6a8l -
(-) 		9 / 11 ASP A   9
PHE A  14
LEU A  21
ASP A  53
GLU A  64
PHE A  68
HIS A  71
TYR A 106
ILE A 135
 None
None
None
ZN  A 200 (-2.7A)
ZN  A 200 (-2.4A)
None
ZN  A 200 (-3.4A)
None
None
 0.72A 3o94D-6a8lA:
33.9		 3o94D-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 6a8l -
(-) 		5 / 10 ILE A 151
ILE A 153
SER A 107
LEU A 138
HIS A 172
 None
 1.28A 3qgzA-6a8lA:
undetectable		 3qgzA-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_A_NIOA311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 6a8l -
(-) 		5 / 9 ASP A   9
LEU A  21
ASP A  53
HIS A  71
LYS A 103
 None
None
ZN  A 200 (-2.7A)
ZN  A 200 (-3.4A)
None
 0.72A 3r2jA-6a8lA:
23.1		 3r2jA-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_A_NIOA311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 6a8l -
(-) 		5 / 9 ASP A   9
LEU A  21
ASP A  53
LYS A 103
CYH A 136
 None
None
ZN  A 200 (-2.7A)
None
None
 1.17A 3r2jA-6a8lA:
23.1		 3r2jA-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_B_NIOB311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 6a8l -
(-) 		5 / 11 ASP A   9
LEU A  21
ASP A  53
LYS A 103
CYH A 136
 None
None
ZN  A 200 (-2.7A)
None
None
 1.19A 3r2jB-6a8lA:
22.7		 3r2jB-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_B_NIOB311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 6a8l -
(-) 		7 / 11 ASP A   9
PHE A  14
LEU A  21
ASP A  53
HIS A  71
LYS A 103
TYR A 106
 None
None
None
ZN  A 200 (-2.7A)
ZN  A 200 (-3.4A)
None
None
 0.71A 3r2jB-6a8lA:
22.7		 3r2jB-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_C_NIOC311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 6a8l -
(-) 		6 / 12 ASP A   9
LEU A  21
ASP A  53
HIS A  55
LYS A 103
CYH A 136
 None
None
ZN  A 200 (-2.7A)
ZN  A 200 (-3.2A)
None
None
 1.13A 3r2jC-6a8lA:
23.1		 3r2jC-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_C_NIOC311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 6a8l -
(-) 		8 / 12 ASP A   9
PHE A  14
LEU A  21
ASP A  53
HIS A  55
HIS A  71
LYS A 103
TYR A 106
 None
None
None
ZN  A 200 (-2.7A)
ZN  A 200 (-3.2A)
ZN  A 200 (-3.4A)
None
None
 0.65A 3r2jC-6a8lA:
23.1		 3r2jC-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_D_NIOD311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 6a8l -
(-) 		5 / 11 ASP A   9
LEU A  21
ASP A  53
LYS A 103
CYH A 136
 None
None
ZN  A 200 (-2.7A)
None
None
 1.17A 3r2jD-6a8lA:
23.0		 3r2jD-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_D_NIOD311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 6a8l -
(-) 		7 / 11 ASP A   9
PHE A  14
LEU A  21
ASP A  53
HIS A  71
LYS A 103
TYR A 106
 None
None
None
ZN  A 200 (-2.7A)
ZN  A 200 (-3.4A)
None
None
 0.69A 3r2jD-6a8lA:
23.0		 3r2jD-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6a8l -
(-) 		5 / 11 THR A 140
ALA A 144
LEU A 126
PHE A 149
SER A 107
 None
 1.46A 4claA-6a8lA:
undetectable		 4claA-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 6a8l -
(-) 		5 / 12 LEU A  88
PHE A  50
TYR A  10
ALA A 129
LEU A   5
 None
 1.20A 4j7xB-6a8lA:
5.9		 4j7xB-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5eeuA-6a8lA:
undetectable
5eeuB-6a8lA:
undetectable		 5eeuA-6a8lA:
undetectable
5eeuB-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5eeuB-6a8lA:
undetectable
5eeuC-6a8lA:
undetectable		 5eeuB-6a8lA:
undetectable
5eeuC-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5eeuC-6a8lA:
undetectable
5eeuD-6a8lA:
undetectable		 5eeuC-6a8lA:
undetectable
5eeuD-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.44A 5eeuA-6a8lA:
undetectable
5eeuK-6a8lA:
undetectable		 5eeuA-6a8lA:
undetectable
5eeuK-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5eevB-6a8lA:
undetectable
5eevC-6a8lA:
undetectable		 5eevB-6a8lA:
undetectable
5eevC-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5eevC-6a8lA:
undetectable
5eevD-6a8lA:
undetectable		 5eevC-6a8lA:
undetectable
5eevD-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5eevH-6a8lA:
undetectable
5eevI-6a8lA:
undetectable		 5eevH-6a8lA:
undetectable
5eevI-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.44A 5eevA-6a8lA:
undetectable
5eevK-6a8lA:
undetectable		 5eevA-6a8lA:
undetectable
5eevK-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5eewB-6a8lA:
undetectable
5eewC-6a8lA:
undetectable		 5eewB-6a8lA:
undetectable
5eewC-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5eewC-6a8lA:
undetectable
5eewD-6a8lA:
undetectable		 5eewC-6a8lA:
undetectable
5eewD-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.44A 5eewA-6a8lA:
undetectable
5eewK-6a8lA:
undetectable		 5eewA-6a8lA:
undetectable
5eewK-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5eexB-6a8lA:
undetectable
5eexC-6a8lA:
undetectable		 5eexB-6a8lA:
undetectable
5eexC-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5eexC-6a8lA:
undetectable
5eexD-6a8lA:
undetectable		 5eexC-6a8lA:
undetectable
5eexD-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 10 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.44A 5eexA-6a8lA:
undetectable
5eexK-6a8lA:
undetectable		 5eexA-6a8lA:
undetectable
5eexK-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5eeyB-6a8lA:
undetectable
5eeyC-6a8lA:
undetectable		 5eeyB-6a8lA:
undetectable
5eeyC-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5eeyC-6a8lA:
undetectable
5eeyD-6a8lA:
undetectable		 5eeyC-6a8lA:
undetectable
5eeyD-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5eeyH-6a8lA:
undetectable
5eeyI-6a8lA:
undetectable		 5eeyH-6a8lA:
undetectable
5eeyI-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.44A 5eeyA-6a8lA:
undetectable
5eeyK-6a8lA:
undetectable		 5eeyA-6a8lA:
undetectable
5eeyK-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5eezB-6a8lA:
undetectable
5eezC-6a8lA:
undetectable		 5eezB-6a8lA:
undetectable
5eezC-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5eezC-6a8lA:
undetectable
5eezD-6a8lA:
undetectable		 5eezC-6a8lA:
undetectable
5eezD-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5eezH-6a8lA:
undetectable
5eezI-6a8lA:
undetectable		 5eezH-6a8lA:
undetectable
5eezI-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.44A 5eezA-6a8lA:
undetectable
5eezK-6a8lA:
undetectable		 5eezA-6a8lA:
undetectable
5eezK-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5ef0B-6a8lA:
undetectable
5ef0C-6a8lA:
undetectable		 5ef0B-6a8lA:
undetectable
5ef0C-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5ef0C-6a8lA:
undetectable
5ef0D-6a8lA:
undetectable		 5ef0C-6a8lA:
undetectable
5ef0D-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5ef0H-6a8lA:
undetectable
5ef0I-6a8lA:
undetectable		 5ef0H-6a8lA:
undetectable
5ef0I-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 10 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.44A 5ef0A-6a8lA:
undetectable
5ef0K-6a8lA:
undetectable		 5ef0A-6a8lA:
undetectable
5ef0K-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5ef1B-6a8lA:
undetectable
5ef1C-6a8lA:
undetectable		 5ef1B-6a8lA:
undetectable
5ef1C-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5ef1C-6a8lA:
undetectable
5ef1D-6a8lA:
undetectable		 5ef1C-6a8lA:
undetectable
5ef1D-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5ef1H-6a8lA:
undetectable
5ef1I-6a8lA:
undetectable		 5ef1H-6a8lA:
undetectable
5ef1I-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.44A 5ef1A-6a8lA:
undetectable
5ef1K-6a8lA:
undetectable		 5ef1A-6a8lA:
undetectable
5ef1K-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.47A 5ef2B-6a8lA:
undetectable
5ef2C-6a8lA:
undetectable		 5ef2B-6a8lA:
undetectable
5ef2C-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5ef2C-6a8lA:
undetectable
5ef2D-6a8lA:
undetectable		 5ef2C-6a8lA:
undetectable
5ef2D-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5ef2H-6a8lA:
undetectable
5ef2I-6a8lA:
undetectable		 5ef2H-6a8lA:
undetectable
5ef2I-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 GLY A 130
ALA A  51
HIS A 154
ILE A   8
THR A  38
 None
 1.44A 5ef2A-6a8lA:
undetectable
5ef2K-6a8lA:
undetectable		 5ef2A-6a8lA:
undetectable
5ef2K-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.49A 5ef3C-6a8lA:
undetectable
5ef3D-6a8lA:
undetectable		 5ef3C-6a8lA:
undetectable
5ef3D-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6a8l -
(-) 		5 / 9 THR A  38
GLY A 130
ALA A  51
HIS A 154
ILE A   8
 None
 1.48A 5ef3H-6a8lA:
undetectable
5ef3I-6a8lA:
undetectable		 5ef3H-6a8lA:
undetectable
5ef3I-6a8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 6a8l -
(-) 		5 / 12 GLY A 178
ASN A 175
ALA A 169
VAL A 142
TYR A 145
 None
 1.23A 5kbwB-6a8lA:
undetectable		 5kbwB-6a8lA:
undetectable