SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6al5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 6al5 B-LYMPHOCYTE ANTIGEN
CD19
(Homo
sapiens) 		3 / 3 TRP A  52
VAL A  28
ARG A 277
 None
 0.76A 3b0wA-6al5A:
undetectable		 3b0wA-6al5A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6al5 B-LYMPHOCYTE ANTIGEN
CD19
(Homo
sapiens) 		5 / 10 GLY A  92
GLY A  93
THR A 112
TYR A  95
GLU A 120
 None
 1.39A 3fw1A-6al5A:
undetectable		 3fw1A-6al5A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_A_SAMA801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 6al5 B-LYMPHOCYTE ANTIGEN
CD19
(Homo
sapiens) 		5 / 12 PRO A 102
SER A 224
THR A 215
VAL A 241
LEU A  62
 None
 1.18A 3v8vA-6al5A:
undetectable		 3v8vA-6al5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 6al5 B-LYMPHOCYTE ANTIGEN
CD19
(Homo
sapiens) 		5 / 11 LEU A 225
VAL A  87
LEU A 196
LEU A  68
LEU A  82
 None
 1.26A 4or0B-6al5A:
undetectable		 4or0B-6al5A:
8.66