SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6alk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 6alk -
(-) 		5 / 12 ILE A  56
ALA A  37
GLY A 142
ALA A  34
ILE A  38
 None
 0.92A 1bx4A-6alkA:
undetectable		 1bx4A-6alkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 6alk -
(-) 		4 / 6 LEU A  95
GLN A 132
GLU A 130
ILE A 133
 None
 1.10A 2fcnA-6alkA:
undetectable
2fcnB-6alkA:
undetectable		 2fcnA-6alkA:
undetectable
2fcnB-6alkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 6alk -
(-) 		5 / 12 GLY A  48
GLY A  46
GLU A  45
VAL A  23
ILE A  71
 None
 0.98A 2wa2A-6alkA:
undetectable		 2wa2A-6alkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 6alk -
(-) 		5 / 12 GLY A  48
GLY A  46
GLU A  45
VAL A  23
ILE A  71
 None
 0.95A 2wa2B-6alkA:
undetectable		 2wa2B-6alkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APT_B_ACTB311_0
(METHYLENETETRAHYDROF
OLATE REDUCTASE)		 6alk -
(-) 		5 / 9 GLU A 139
HIS A  69
LEU A  85
ALA A  99
ILE A  98
 None
 1.01A 3aptB-6alkA:
undetectable		 3aptB-6alkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 6alk -
(-) 		5 / 12 GLY A  48
GLY A  46
GLU A  45
VAL A  23
ILE A  71
 None
 1.05A 5njvD-6alkA:
undetectable		 5njvD-6alkA:
undetectable