SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6all'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		3 / 3 ARG A 124
VAL A  61
TRP A 301
 None
 1.24A 1vagA-6allA:
undetectable		 1vagA-6allA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		5 / 11 ARG A 102
GLY A 304
VAL A  61
GLU A  59
ARG A 214
 None
None
None
None
PE3  A 401 (-2.9A)
 1.48A 1vhwA-6allA:
undetectable
1vhwD-6allA:
undetectable		 1vhwA-6allA:
21.80
1vhwD-6allA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		5 / 11 ARG A 102
GLY A 304
VAL A  61
GLU A  59
ARG A 214
 None
None
None
None
PE3  A 401 (-2.9A)
 1.48A 1vhwC-6allA:
undetectable
1vhwE-6allA:
undetectable		 1vhwC-6allA:
21.80
1vhwE-6allA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		5 / 11 ARG A 214
ARG A 102
GLY A 304
VAL A  61
GLU A  59
 PE3  A 401 (-2.9A)
None
None
None
None
 1.48A 1vhwC-6allA:
undetectable
1vhwE-6allA:
undetectable		 1vhwC-6allA:
21.80
1vhwE-6allA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		5 / 10 ARG A 214
ARG A 102
GLY A 304
VAL A  61
GLU A  59
 PE3  A 401 (-2.9A)
None
None
None
None
 1.48A 1vhwB-6allA:
undetectable
1vhwF-6allA:
undetectable		 1vhwB-6allA:
21.80
1vhwF-6allA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		4 / 7 ILE A 302
PHE A 182
PHE A 151
GLY A 244
 None
 1.04A 3em0B-6allA:
undetectable		 3em0B-6allA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		5 / 12 HIS A  41
ILE A  39
THR A  46
ILE A 161
ILE A 119
 None
 1.18A 3kpbC-6allA:
undetectable		 3kpbC-6allA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		5 / 12 VAL A  61
PHE A 141
VAL A  55
LEU A 117
ILE A  39
 None
 1.04A 3w67D-6allA:
undetectable		 3w67D-6allA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		5 / 11 GLY A  75
ARG A 102
VAL A  99
PRO A 115
ILE A 118
 None
 1.14A 4j4vA-6allA:
undetectable		 4j4vA-6allA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		5 / 9 ALA A 313
LEU A 296
ILE A 262
ILE A 199
ALA A 185
 None
 1.00A 5nunA-6allA:
undetectable		 5nunA-6allA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		5 / 12 ALA A  52
PRO A  51
GLY A 166
LYS A 167
ASP A 116
 None
 1.27A 5wwsB-6allA:
undetectable		 5wwsB-6allA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY6_A_VORA501_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		5 / 9 TYR A 294
ALA A 202
ALA A 200
THR A 234
LEU A 231
 None
 1.35A 6ay6A-6allA:
undetectable		 6ay6A-6allA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC
(Bacillus
anthracis) 		4 / 7 LEU A 132
VAL A  99
LEU A  58
LEU A 113
 None
 0.72A 6g9bA-6allA:
undetectable
6g9bB-6allA:
undetectable		 6g9bA-6allA:
16.07
6g9bB-6allA:
12.67