SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6amn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 10 ALA A  38
GLU A  41
LEU A  21
ILE A  76
LEU A  30
 None
 1.38A 1a52A-6amnA:
undetectable		 1a52A-6amnA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 10 ALA A  38
GLU A  41
LEU A  21
ILE A  76
LEU A  30
 None
 1.42A 1a52B-6amnA:
undetectable		 1a52B-6amnA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 9 ALA A  38
GLU A  41
LEU A  21
ILE A  76
LEU A  30
 None
 1.42A 1ereA-6amnA:
undetectable		 1ereA-6amnA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 9 ALA A  38
GLU A  41
LEU A  21
ILE A  76
LEU A  30
 None
 1.43A 1ereB-6amnA:
undetectable		 1ereB-6amnA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 9 ALA A  38
GLU A  41
LEU A  21
ILE A  76
LEU A  30
 None
 1.43A 1ereC-6amnA:
undetectable		 1ereC-6amnA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 9 ALA A  38
GLU A  41
LEU A  21
ILE A  76
LEU A  30
 None
 1.41A 1ereD-6amnA:
undetectable		 1ereD-6amnA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 332
LYS A 327
VAL A 325
 None
 0.93A 1l2iA-6amnA:
undetectable		 1l2iA-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 282
ALA A 315
ILE A 221
ILE A 338
 None
 0.82A 1oniD-6amnA:
undetectable
1oniF-6amnA:
undetectable		 1oniD-6amnA:
undetectable
1oniF-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 11 SER A 275
LEU A 278
THR A 277
ILE A 313
VAL A 312
 None
 1.21A 1pkvA-6amnA:
undetectable
1pkvB-6amnA:
undetectable		 1pkvA-6amnA:
22.64
1pkvB-6amnA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 11 VAL A 312
SER A 275
LEU A 278
THR A 277
ILE A 313
 None
 1.19A 1pkvA-6amnA:
undetectable
1pkvB-6amnA:
undetectable		 1pkvA-6amnA:
22.64
1pkvB-6amnA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 10 ALA A  38
GLU A  41
LEU A  21
ILE A  76
LEU A  30
 None
 1.29A 1qkuA-6amnA:
undetectable		 1qkuA-6amnA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 10 ALA A  38
GLU A  41
LEU A  21
ILE A  76
LEU A  30
 None
 1.29A 1qkuB-6amnA:
undetectable		 1qkuB-6amnA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 10 ALA A  38
GLU A  41
LEU A  21
ILE A  76
LEU A  30
 None
 1.29A 1qkuC-6amnA:
undetectable		 1qkuC-6amnA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		4 / 8 VAL A  48
PRO A  49
THR A  42
PRO A  43
 None
 0.80A 2v32C-6amnA:
undetectable
2v32D-6amnA:
undetectable		 2v32C-6amnA:
undetectable
2v32D-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		4 / 7 TYR A  62
PHE A  65
PHE A 130
ILE A  40
 None
 1.10A 2zseA-6amnA:
undetectable		 2zseA-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 167
LEU A 246
SER A 245
MET A 174
 None
 0.98A 3vhuA-6amnA:
undetectable		 3vhuA-6amnA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 345
VAL A 349
LEU A 352
ASN A 318
 None
 0.73A 4e1gB-6amnA:
undetectable		 4e1gB-6amnA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 345
GLU A 191
GLU A 192
 None
 0.91A 5jsdB-6amnA:
undetectable
5jsdC-6amnA:
undetectable		 5jsdB-6amnA:
6.82
5jsdC-6amnA:
6.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 212
GLY A 314
THR A 317
GLU A 285
ILE A 216
 None
 1.03A 5wz1A-6amnA:
undetectable		 5wz1A-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 212
GLY A 314
THR A 317
GLU A 285
ILE A 216
 None
 1.00A 5wz1C-6amnA:
undetectable		 5wz1C-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 212
GLY A 314
THR A 317
GLU A 285
ILE A 216
 None
 0.98A 5wz1D-6amnA:
undetectable		 5wz1D-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 212
GLY A 314
THR A 317
GLU A 285
ILE A 216
 None
 0.99A 5wz1E-6amnA:
undetectable		 5wz1E-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 212
GLY A 314
THR A 317
GLU A 285
ILE A 216
 None
 0.97A 5wz1F-6amnA:
undetectable		 5wz1F-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 212
GLY A 314
THR A 317
GLU A 285
ILE A 216
 None
 1.03A 5wz1G-6amnA:
2.1		 5wz1G-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 212
GLY A 314
THR A 317
GLU A 285
ILE A 216
 None
 0.99A 5wz1H-6amnA:
undetectable		 5wz1H-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 312
LEU A 246
LEU A 269
ILE A 300
ALA A 304
 None
 1.40A 5xprA-6amnA:
undetectable		 5xprA-6amnA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 10 LEU A  73
ILE A 126
LEU A  15
ALA A  18
LEU A  30
 None
 1.18A 5y7pD-6amnA:
undetectable		 5y7pD-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 10 LEU A  73
ILE A 126
LEU A  15
ALA A  18
LEU A  30
 None
 1.20A 5y7pH-6amnA:
undetectable		 5y7pH-6amnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 6amn HEAT SHOCK PROTEIN
104
(Saccharomyces
cerevisiae) 		5 / 10 ALA A  38
GLU A  41
LEU A  21
ILE A  76
LEU A  30
 None
 1.36A 6cbzB-6amnA:
undetectable		 6cbzB-6amnA:
18.68