SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6an5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 6an5 ABC TRANSPORTER
(Aquifex
aeolicus) 		4 / 7 GLU A  89
ALA A 151
ASN A 107
ALA A 155
 None
 1.06A 2ejfA-6an5A:
undetectable		 2ejfA-6an5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 6an5 ABC TRANSPORTER
(Aquifex
aeolicus) 		4 / 7 GLU A  89
ALA A 151
ASN A 107
ALA A 155
 None
 1.03A 2zgwA-6an5A:
undetectable		 2zgwA-6an5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 6an5 ABC TRANSPORTER
(Aquifex
aeolicus) 		4 / 6 GLU A  89
ALA A 151
ASN A 107
ALA A 155
 None
 1.06A 2zgwB-6an5A:
undetectable		 2zgwB-6an5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 6an5 ABC TRANSPORTER
(Aquifex
aeolicus) 		4 / 8 ILE A 104
LEU A 122
ILE A 126
ASP A 132
 None
 0.94A 4dtaB-6an5A:
undetectable		 4dtaB-6an5A:
27.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 6an5 ABC TRANSPORTER
(Aquifex
aeolicus) 		5 / 10 LEU A  90
ILE A 154
GLY A  93
PHE A 152
SER A 153
 None
 1.07A 4fakA-6an5A:
undetectable		 4fakA-6an5A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 6an5 ABC TRANSPORTER
(Aquifex
aeolicus) 		4 / 5 HIS A 157
ILE A 118
ILE A 154
TYR A 105
 None
 1.20A 5dnuA-6an5A:
undetectable		 5dnuA-6an5A:
22.00