SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ane'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		4 / 6 PRO A 154
PHE A 174
GLU A 204
GLN A 155
 None
 0.97A 1l2iB-6aneA:
undetectable		 1l2iB-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		4 / 5 GLY A 137
ILE A 141
VAL A 129
SER A  97
 None
 1.10A 1rs7A-6aneA:
undetectable		 1rs7A-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 PRO A  72
TYR A  42
THR A  83
ILE A  56
SER A  65
 None
 1.05A 1xoqA-6aneA:
undetectable		 1xoqA-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 PRO A  72
TYR A  42
THR A  83
ILE A  56
SER A  66
 None
 1.33A 1xoqA-6aneA:
undetectable		 1xoqA-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 PRO A  72
TYR A  42
THR A  83
ILE A  56
SER A  65
 None
 1.06A 1xoqB-6aneA:
undetectable		 1xoqB-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 PRO A  72
TYR A  42
THR A  83
ILE A  56
SER A  66
 None
 1.33A 1xoqB-6aneA:
undetectable		 1xoqB-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		4 / 4 GLY A  59
SER A 133
ILE A 181
HIS A 210
 None
 1.19A 1yajJ-6aneA:
8.4		 1yajJ-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 PRO A  72
TYR A  42
THR A  83
ILE A  56
SER A  65
 None
 1.06A 3g4lA-6aneA:
undetectable		 3g4lA-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 PRO A  72
TYR A  42
THR A  83
ILE A  56
SER A  66
 None
 1.31A 3g4lA-6aneA:
undetectable		 3g4lA-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		3 / 3 SER A  94
ASP A 159
ASP A  91
 None
 0.93A 3iv6C-6aneA:
undetectable		 3iv6C-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 GLY A 135
ALA A  62
PRO A 157
ALA A 156
PRO A 154
 None
 0.93A 3jayA-6aneA:
undetectable		 3jayA-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 GLY A 135
ALA A  62
PRO A 157
ALA A 156
PRO A 154
 None
 1.00A 3jb1A-6aneA:
undetectable		 3jb1A-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 GLY A 135
ALA A  62
PRO A 157
ALA A 156
PRO A 154
 None
 0.91A 3jb3A-6aneA:
undetectable		 3jb3A-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 TRP A  70
ALA A  38
ILE A  82
ILE A  54
MET A 130
 None
 1.05A 3ld6A-6aneA:
undetectable		 3ld6A-6aneA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		4 / 5 GLY A 137
ILE A 141
VAL A 129
SER A  97
 None
 1.23A 4d33A-6aneA:
undetectable		 4d33A-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		4 / 5 GLY A 137
ILE A 141
VAL A 129
SER A  97
 None
 1.25A 4d33B-6aneA:
undetectable		 4d33B-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 HIS A 210
ALA A 213
ILE A 191
GLY A 136
GLY A 138
 None
 1.26A 4hfpB-6aneA:
undetectable		 4hfpB-6aneA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 GLY A 131
SER A 139
LEU A 140
ALA A 143
ALA A 152
 None
 1.10A 4uckB-6aneA:
undetectable		 4uckB-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 10 ALA A  53
LEU A 104
ALA A 108
SER A 148
LEU A 149
 None
 1.20A 4zbrA-6aneA:
undetectable		 4zbrA-6aneA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		4 / 7 PRO A  93
ASP A 159
SER A 166
PHE A 164
 None
 1.33A 5a1iA-6aneA:
undetectable		 5a1iA-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 ILE A  82
GLY A  39
ASP A  85
ALA A 103
LEU A 104
 None
 1.21A 5hw4A-6aneA:
undetectable		 5hw4A-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 11 ILE A  82
GLY A  39
ASP A  85
ALA A 103
LEU A 104
 None
 1.18A 5hw4B-6aneA:
undetectable		 5hw4B-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 ILE A  82
GLY A  39
ASP A  85
ALA A 103
LEU A 104
 None
 1.18A 5hw4C-6aneA:
undetectable		 5hw4C-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		3 / 3 GLY A 136
GLY A 135
GLN A 100
 None
 0.46A 5imsA-6aneA:
2.9		 5imsA-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 GLY A 135
SER A 186
ASP A 193
ARG A 258
PHE A 202
 None
 1.31A 5zvgA-6aneA:
undetectable		 5zvgA-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		5 / 12 ALA A 213
GLY A 136
GLY A 131
ARG A  96
TRP A 158
 None
 1.22A 6clxA-6aneA:
undetectable		 6clxA-6aneA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 6ane POLY(ETHYLENE
TEREPHTHALATE)
HYDROLASE
(Ideonella
sakaiensis) 		4 / 5 TYR A  36
GLN A  99
GLY A  71
ILE A  82
 None
 1.48A 6debB-6aneA:
2.6		 6debB-6aneA:
15.85