SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ank'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_B_CYZB329_1
(GLUTAMINE RECEPTOR 2)		 6ank SYNAPTOTAGMIN-7
(Rattus
norvegicus) 		5 / 9 LYS A 176
SER A 239
LEU A 224
LEU A 257
LYS A 255
 None
 1.49A 1lbcB-6ankA:
undetectable		 1lbcB-6ankA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 6ank SYNAPTOTAGMIN-7
(Rattus
norvegicus) 		5 / 12 LYS A 176
SER A 239
LEU A 224
LEU A 257
LYS A 255
 None
 1.50A 1lbcA-6ankA:
undetectable
1lbcC-6ankA:
undetectable		 1lbcA-6ankA:
21.54
1lbcC-6ankA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 6ank SYNAPTOTAGMIN-7
(Rattus
norvegicus) 		4 / 7 PHE A 206
LEU A 179
LEU A 242
LEU A 219
 None
 0.76A 3bgdB-6ankA:
undetectable		 3bgdB-6ankA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 6ank SYNAPTOTAGMIN-7
(Rattus
norvegicus) 		4 / 8 ILE A 370
LEU A 272
GLU A 269
ALA A 290
 None
 0.70A 3r9tA-6ankA:
undetectable		 3r9tA-6ankA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 6ank SYNAPTOTAGMIN-7
(Rattus
norvegicus) 		4 / 7 ILE A 370
LEU A 272
GLU A 269
ALA A 290
 None
 0.67A 3r9tB-6ankA:
undetectable		 3r9tB-6ankA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 6ank SYNAPTOTAGMIN-7
(Rattus
norvegicus) 		3 / 3 ASP A 303
ARG A 327
ASP A 365
 CA  A 505 (-3.3A)
None
CA  A 506 (-3.4A)
 0.81A 4fp9C-6ankA:
undetectable		 4fp9C-6ankA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 6ank SYNAPTOTAGMIN-7
(Rattus
norvegicus) 		5 / 12 LEU A 257
GLY A 137
ARG A 138
SER A 171
PHE A 174
 None
 1.36A 5czyA-6ankA:
undetectable		 5czyA-6ankA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 6ank SYNAPTOTAGMIN-7
(Rattus
norvegicus) 		4 / 6 GLY A 144
TYR A 145
LEU A 219
VAL A 245
 None
 0.93A 5x80A-6ankA:
undetectable
5x80B-6ankA:
undetectable		 5x80A-6ankA:
20.21
5x80B-6ankA:
20.21