SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6anr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_A_DESA129_1
(TRANSTHYRETIN)		 6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS
(Escherichia
coli) 		4 / 4 LYS A 166
LEU A 164
LEU A 161
SER A 158
 None
 1.42A 1tt6A-6anrA:
undetectable		 1tt6A-6anrA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS
(Escherichia
coli) 		3 / 3 ARG A  90
ASP A  98
ASP A 101
 None
 0.80A 2ejtA-6anrA:
undetectable		 2ejtA-6anrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS
(Escherichia
coli) 		3 / 3 GLU A  81
HIS A  65
GLU A  80
 None
 0.82A 2x45B-6anrA:
undetectable		 2x45B-6anrA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS
(Escherichia
coli) 		3 / 3 GLU A  81
HIS A  65
GLU A  80
 None
 0.82A 2x45C-6anrA:
undetectable		 2x45C-6anrA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS
(Escherichia
coli) 		4 / 8 TRP A 136
HIS A  67
PHE A  78
TRP A  59
 None
 1.41A 3v35A-6anrA:
undetectable		 3v35A-6anrA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS
(Escherichia
coli) 		4 / 5 ARG A 111
VAL A  53
LEU A  56
SER A  54
 None
 1.20A 4e1gA-6anrA:
undetectable		 4e1gA-6anrA:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS
(Escherichia
coli) 		3 / 3 HIS A  67
GLY A 143
ILE A 146
 None
 0.58A 4k50A-6anrA:
undetectable		 4k50A-6anrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS
(Escherichia
coli) 		3 / 3 HIS A  67
GLY A 143
ILE A 146
 None
 0.56A 4k50I-6anrA:
undetectable		 4k50I-6anrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS
(Escherichia
coli) 		3 / 3 ARG A  90
ASP A  98
ASP A 101
 None
 0.85A 4kicB-6anrA:
undetectable		 4kicB-6anrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS
(Escherichia
coli) 		5 / 12 LEU A 112
ILE A  57
THR A 103
LEU A 161
LEU A  52
 None
 1.22A 5nfjC-6anrA:
undetectable		 5nfjC-6anrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 6anr COLIBACTIN
SELF-PROTECTION
PROTEIN CLBS
(Escherichia
coli) 		4 / 6 HIS A  67
ASN A 149
LEU A 131
GLN A 147
 None
 1.39A 5xdhA-6anrA:
undetectable
5xdhC-6anrA:
undetectable		 5xdhA-6anrA:
18.52
5xdhC-6anrA:
18.52