SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6anu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 6anu SPECTRIN BETA CHAIN,
NON-ERYTHROCYTIC 2
(Homo
sapiens) 		5 / 12 PHE f1125
LEU f1123
ALA f1122
LEU f1152
LEU f1094
 None
 1.14A 1og5A-6anuf:
undetectable		 1og5A-6anuf:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 6anu SPECTRIN BETA CHAIN,
NON-ERYTHROCYTIC 2
(Homo
sapiens) 		4 / 6 LEU f1150
VAL f1153
VAL f1078
ASP f1080
 None
 1.19A 2zawA-6anuf:
undetectable		 2zawA-6anuf:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6anu SPECTRIN BETA CHAIN,
NON-ERYTHROCYTIC 2
(Homo
sapiens) 		5 / 12 VAL f1119
LEU f1103
VAL f1074
ILE f1156
LEU f1098
 None
 0.99A 3w68B-6anuf:
undetectable		 3w68B-6anuf:
22.37