SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6any'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)
6any BM4233, ISOFORM B
(Brugia
malayi)
4 / 6 LEU A 176
TYR A 100
ILE A 166
GLY A 120
None
0.67A 2du8A-6anyA:
undetectable
2du8A-6anyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)
6any BM4233, ISOFORM B
(Brugia
malayi)
4 / 6 LEU A 176
TYR A 100
ILE A 166
GLY A 120
None
0.67A 2du8B-6anyA:
undetectable
2du8B-6anyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)
6any BM4233, ISOFORM B
(Brugia
malayi)
3 / 3 HIS A 181
TRP A  67
SER A  87
None
1.14A 4lrhD-6anyA:
undetectable
4lrhD-6anyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)
6any BM4233, ISOFORM B
(Brugia
malayi)
4 / 6 GLU A  72
GLY A  22
ARG A  29
ARG A 112
None
1.29A 5jcnB-6anyA:
undetectable
5jcnB-6anyA:
undetectable