SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ao9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_A_DVAA6_0
(GRAMICIDIN A)		 6ao9 BACTERIO-RHODOPSIN/G
UANYLYL CYCLASE 1
FUSION PROTEIN
(Blastocladiella
emersonii) 		3 / 3 ALA A 445
VAL A 557
TRP A 565
 None
 0.89A 1bdwA-6ao9A:
undetectable
1bdwB-6ao9A:
undetectable		 1bdwA-6ao9A:
8.55
1bdwB-6ao9A:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 6ao9 BACTERIO-RHODOPSIN/G
UANYLYL CYCLASE 1
FUSION PROTEIN
(Blastocladiella
emersonii) 		4 / 8 ILE A 542
ASP A 501
ARG A 467
GLU A 540
 None
 0.96A 2cdqA-6ao9A:
3.9		 2cdqA-6ao9A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 6ao9 BACTERIO-RHODOPSIN/G
UANYLYL CYCLASE 1
FUSION PROTEIN
(Blastocladiella
emersonii) 		5 / 11 SER A 456
PHE A 523
ASP A 526
ALA A 520
ILE A 531
 None
 1.31A 4uuuB-6ao9A:
undetectable		 4uuuB-6ao9A:
20.92