SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6aom'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 6aom ENDOPLASMIN
(Canis
lupus) 		5 / 12 LEU A 104
LEU A 159
ILE A 247
PHE A 199
PHE A  78
 VC5  A 409 (-4.5A)
None
VC5  A 409 (-4.4A)
VC5  A 409 (-4.2A)
None
 0.94A 2ygqA-6aomA:
undetectable		 2ygqA-6aomA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 6aom ENDOPLASMIN
(Canis
lupus) 		4 / 4 LEU A 241
GLY A 242
GLY A 244
THR A 150
 None
 0.94A 3si7A-6aomA:
undetectable		 3si7A-6aomA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 6aom ENDOPLASMIN
(Canis
lupus) 		4 / 6 ASN A 239
GLY A 238
ASP A 235
ILE A 222
 None
 0.70A 3w9tF-6aomA:
undetectable		 3w9tF-6aomA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 6aom ENDOPLASMIN
(Canis
lupus) 		5 / 12 GLY A 193
LEU A  93
THR A 171
ILE A 166
PHE A 195
 None
 1.37A 4p6xA-6aomA:
undetectable		 4p6xA-6aomA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 6aom ENDOPLASMIN
(Canis
lupus) 		5 / 12 GLY A 193
LEU A  93
THR A 171
ILE A 166
PHE A 195
 None
 1.36A 4p6xE-6aomA:
undetectable		 4p6xE-6aomA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 6aom ENDOPLASMIN
(Canis
lupus) 		5 / 12 GLY A 193
LEU A  93
THR A 171
ILE A 166
PHE A 195
 None
 1.38A 4p6xG-6aomA:
undetectable		 4p6xG-6aomA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 6aom ENDOPLASMIN
(Canis
lupus) 		5 / 12 GLY A 193
LEU A  93
THR A 171
ILE A 166
PHE A 195
 None
 1.39A 4p6xI-6aomA:
undetectable		 4p6xI-6aomA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 6aom ENDOPLASMIN
(Canis
lupus) 		3 / 3 CYH A 138
LYS A 137
HIS A 146
 None
P33  A 402 (-2.6A)
P33  A 402 ( 4.0A)
 1.18A 5js5A-6aomA:
undetectable		 5js5A-6aomA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 6aom ENDOPLASMIN
(Canis
lupus) 		3 / 3 VAL A 232
SER A 231
TRP A 223
 None
GOL  A 410 (-3.4A)
None
 0.99A 5jwaA-6aomA:
undetectable		 5jwaA-6aomA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 6aom ENDOPLASMIN
(Canis
lupus) 		4 / 7 GLY A 151
ALA A 108
ASP A 113
ASN A 129
 None
VC5  A 409 ( 4.7A)
None
None
 0.92A 5mvsA-6aomA:
undetectable		 5mvsA-6aomA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 6aom ENDOPLASMIN
(Canis
lupus) 		5 / 12 LEU A 144
VAL A 250
ALA A 202
TRP A 223
ALA A 206
 None
 1.16A 5tzoB-6aomA:
undetectable		 5tzoB-6aomA:
21.98